| Literature DB >> 28250476 |
Yongzhi Yin1, Ximeng Chen1, Heyu Wu2, Sergey Komarov2, Alfred Garson3, Qiang Li4, Qingzhen Guo3, Henric Krawczynski3, Ling-Jian Meng5, Yuan-Chuan Tai2.
Abstract
We are currently investigating the feasibility of using highly pixelated Cadmium Zinc Telluride (CdZnTe) detectors for sub-500 μm resolution PET imaging applications. A 20 mm × 20 mm × 5 mm CdZnTe substrate was fabricated with 350 μm pitch pixels (250 μm anode pixels with 100 μm gap) and coplanar cathode. Charge sharing among the pixels of a 350 μm pitch detector was studied using collimated 122 keV and 511 keV gamma ray sources. For a 350 μm pitch CdZnTe detector, scatter plots of the charge signal of two neighboring pixels clearly show more charge sharing when the collimated beam hits the gap between adjacent pixels. Using collimated Co-57 and Ge-68 sources, we measured the count profiles and estimated the intrinsic spatial resolution of 350 μm pitch detector biased at -1000 V. Depth of interaction was analyzed based on two methods, i.e., cathode/anode ratio and electron drift time, in both 122 keV and 511 keV measurements. For single-pixel photopeak events, a linear correlation between cathode/anode ratio and electron drift time was shown, which would be useful for estimating the DOI information and preserving image resolution in CdZnTe PET imaging applications.Entities:
Keywords: CdZnTe detectors; charge sharing; imaging applications; spatial resolution
Year: 2012 PMID: 28250476 PMCID: PMC5328192 DOI: 10.1109/TNS.2012.2213611
Source DB: PubMed Journal: IEEE Trans Nucl Sci ISSN: 0018-9499 Impact factor: 1.679