Literature DB >> 28250475

An Intensified EMCCD Camera for Low Energy Gamma Ray Imaging Applications.

L J Meng1.   

Abstract

This paper presents the design and feasibility study of a very-high resolution gamma camera for detecting 27-35 keV X and gamma rays emitted by I-125 labelled radiotracers. This detector consists of a newly developed Electron-multiplying CCD (EMCCD) sensor and a de-magnifier tube coupled to a thin layer of scintillator. A prototype detector was developed and experimentally evaluated. This detector has a detection area of ~ 5 cm2. It provided an intrinsic spatial resolution of < 60 µm FWHM and a high signal-to-noise ratio for detecting the 27-35 keV photons, which ensures an excellent counting efficiency. This detector will be used as the key component for a single photon emission microscope (SPEM) system that is under development.

Entities:  

Keywords:  De-magnifier tube; EMCCD

Year:  2006        PMID: 28250475      PMCID: PMC5328474          DOI: 10.1109/TNS.2006.878574

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  10 in total

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Authors:  Todd E Peterson; Hyunki Kim; Michael J Crawford; Benjamin M Gershman; William C J Hunter; H Bradford Barber; Lars R Furenlid; Donald W Wilson; James M Woolfenden; Harrison H Barrett
Journal:  IEEE Nucl Sci Symp Conf Rec (1997)       Date:  2002-11-10

2.  Compact CT/SPECT Small-Animal Imaging System.

Authors:  George A Kastis; Lars R Furenlid; Donald W Wilson; Todd E Peterson; H Bradford Barber; Harrison H Barrett
Journal:  IEEE Trans Nucl Sci       Date:  2004-02       Impact factor: 1.679

3.  Design and simulation of a high-resolution stationary SPECT system for small animals.

Authors:  Freek J Beekman; Brendan Vastenhouw
Journal:  Phys Med Biol       Date:  2004-10-07       Impact factor: 3.609

4.  Photon-counting versus an integrating CCD-based gamma camera: important consequences for spatial resolution.

Authors:  Freek J Beekman; Gerralt A de Vree
Journal:  Phys Med Biol       Date:  2005-05-25       Impact factor: 3.609

5.  Quantitative autoradiographic studies of dopamine D3 receptors in rat cerebellum using [125I]S(-)5-OH-PIPAT.

Authors:  J M Vessotskie; M P Kung; S Chumpradit; H F Kung
Journal:  Brain Res       Date:  1997-12-05       Impact factor: 3.252

6.  U-SPECT-I: a novel system for submillimeter-resolution tomography with radiolabeled molecules in mice.

Authors:  Freek J Beekman; Frans van der Have; Brendan Vastenhouw; Annemarie J A van der Linden; Peter P van Rijk; J Peter H Burbach; Marten P Smidt
Journal:  J Nucl Med       Date:  2005-07       Impact factor: 10.057

7.  Binding of 125I-iodovinyltetrabenazine to CNS vesicular monoamine transport sites.

Authors:  M P Kung; D J Canney; D Frederick; Z Zhuang; J J Billings; H F Kung
Journal:  Synapse       Date:  1994-11       Impact factor: 2.562

8.  Performance evaluation of a pinhole SPECT system for myocardial perfusion imaging of mice.

Authors:  Max C Wu; Bruce H Hasegawa; Michael W Dae
Journal:  Med Phys       Date:  2002-12       Impact factor: 4.071

9.  Towards in vivo nuclear microscopy: iodine-125 imaging in mice using micro-pinholes.

Authors:  Freek J Beekman; David P McElroy; Frank Berger; Sanjiv S Gambhir; Edward J Hoffman; Simon R Cherry
Journal:  Eur J Nucl Med Mol Imaging       Date:  2002-04-19       Impact factor: 9.236

10.  Characterization of [125I](R)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino] tetralin binding to dopamine D3 receptors in rat olfactory tubercle.

Authors:  K D Burris; T M Filtz; S Chumpradit; M P Kung; C Foulon; J G Hensler; H F Kung; P B Molinoff
Journal:  J Pharmacol Exp Ther       Date:  1994-02       Impact factor: 4.030

  10 in total
  3 in total

1.  Statistical Characterization of Radiological Images: Basic Principles and Recent Progress.

Authors:  Harrison H Barrett; Kyle J Myers
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2007-01-01

2.  SPECT system optimization against a discrete parameter space.

Authors:  L J Meng; N Li
Journal:  Phys Med Biol       Date:  2013-04-15       Impact factor: 3.609

3.  Performance assessment of the single photon emission microscope: high spatial resolution SPECT imaging of small animal organs.

Authors:  J Mejia; M A Reis; A C C Miranda; I R Batista; M R F Barboza; M C Shih; G Fu; C T Chen; L J Meng; R A Bressan; E Amaro
Journal:  Braz J Med Biol Res       Date:  2013-11-06       Impact factor: 2.590

  3 in total

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