Literature DB >> 28129586

Interaction between epigenetic and metabolism in aging stem cells.

Anne Brunet1, Thomas A Rando2.   

Abstract

Aging is accompanied by a decline in tissue function, regeneration, and repair. A large part of this decline is caused by the deterioration of tissue stem cell function. Understanding the mechanisms that drive stem cell aging and how to counteract them is a critical step for enhancing tissue repair and maintenance during aging. Emerging evidence indicates that epigenetic modifiers and metabolism regulators interact to impact lifespan, suggesting that this mechanism may also affect stem cell function with age. This review focuses on the interaction between chromatin and metabolism in the regulation of tissue stem cells during aging. We also discuss how these mechanisms integrate environmental stimuli such as nutrient stress to regulate stem cell function. Finally, this review examines new perspectives for regeneration, rejuvenation, and treatment of age-related decline of stem cell function.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 28129586      PMCID： PMC5482778          DOI： 10.1016/j.ceb.2016.12.009

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  71 in total

Review 1.  Epigenetic regulation of ageing: linking environmental inputs to genomic stability.

Authors:  Bérénice A Benayoun; Elizabeth A Pollina; Anne Brunet
Journal:  Nat Rev Mol Cell Biol       Date:  2015-09-16       Impact factor: 94.444

2.  Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.

Authors:  Verawan Boonsanay; Ting Zhang; Angelina Georgieva; Sawa Kostin; Hui Qi; Xuejun Yuan; Yonggang Zhou; Thomas Braun
Journal:  Cell Stem Cell       Date:  2015-12-05       Impact factor: 24.633

3.  Increased cell-to-cell variation in gene expression in ageing mouse heart.

Authors:  Rumana Bahar; Claudia H Hartmann; Karl A Rodriguez; Ashley D Denny; Rita A Busuttil; Martijn E T Dollé; R Brent Calder; Gary B Chisholm; Brad H Pollock; Christoph A Klein; Jan Vijg
Journal:  Nature       Date:  2006-06-22       Impact factor: 49.962

4.  mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction.

Authors:  Masaki Igarashi; Leonard Guarente
Journal:  Cell       Date:  2016-06-23       Impact factor: 41.582

Review 5.  Cellular Metabolism and Induced Pluripotency.

Authors:  Jun Wu; Alejandro Ocampo; Juan Carlos Izpisua Belmonte
Journal:  Cell       Date:  2016-09-08       Impact factor: 41.582

6.  Dynamics and memory of heterochromatin in living cells.

Authors:  Nathaniel A Hathaway; Oliver Bell; Courtney Hodges; Erik L Miller; Dana S Neel; Gerald R Crabtree
Journal:  Cell       Date:  2012-06-14       Impact factor: 41.582

7.  A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.

Authors:  Sebastian Brandhorst; In Young Choi; Min Wei; Chia Wei Cheng; Sargis Sedrakyan; Gerardo Navarrete; Louis Dubeau; Li Peng Yap; Ryan Park; Manlio Vinciguerra; Stefano Di Biase; Hamed Mirzaei; Mario G Mirisola; Patra Childress; Lingyun Ji; Susan Groshen; Fabio Penna; Patrizio Odetti; Laura Perin; Peter S Conti; Yuji Ikeno; Brian K Kennedy; Pinchas Cohen; Todd E Morgan; Tanya B Dorff; Valter D Longo
Journal:  Cell Metab       Date:  2015-06-18       Impact factor: 27.287

8.  Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Authors:  Allison Mayle; Liubin Yang; Benjamin Rodriguez; Ting Zhou; Edmund Chang; Choladda V Curry; Grant A Challen; Wei Li; David Wheeler; Vivienne I Rebel; Margaret A Goodell
Journal:  Blood       Date:  2015-01-22       Impact factor: 22.113

9.  Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.

Authors:  Mintie Pu; Zhuoyu Ni; Minghui Wang; Xiujuan Wang; Jason G Wood; Stephen L Helfand; Haiyuan Yu; Siu Sylvia Lee
Journal:  Genes Dev       Date:  2015-04-01       Impact factor: 11.361

10.  mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).

Authors:  Joseph T Rodgers; Katherine Y King; Jamie O Brett; Melinda J Cromie; Gregory W Charville; Katie K Maguire; Christopher Brunson; Namrata Mastey; Ling Liu; Chang-Ru Tsai; Margaret A Goodell; Thomas A Rando
Journal:  Nature       Date:  2014-05-25       Impact factor: 49.962
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  31 in total

Review 1.  Cellular Metabolism and Aging.

Authors:  Andre Catic
Journal:  Prog Mol Biol Transl Sci       Date:  2018-02-01       Impact factor: 3.622

2.  Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.

Authors:  Katelyn A Doxtader; Ping Wang; Anna M Scarborough; Dahee Seo; Nicholas K Conrad; Yunsun Nam
Journal:  Mol Cell       Date:  2018-09-06       Impact factor: 17.970

3.  Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility.

Authors:  Janis Koester; Yekaterina A Miroshnikova; Sushmita Ghatak; Carlos Andrés Chacón-Martínez; Jessica Morgner; Xinping Li; Ilian Atanassov; Janine Altmüller; David E Birk; Manuel Koch; Wilhelm Bloch; Michaela Bartusel; Carien M Niessen; Alvaro Rada-Iglesias; Sara A Wickström
Journal:  Nat Cell Biol       Date:  2021-07-08       Impact factor: 28.824

4.  Stem Cell Aging and Regenerative Medicine.

Authors:  Debojyoti De; Parimal Karmakar; Debalina Bhattacharya
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

5.  Covering the Stem Cell Explosion at the 2017 ISSCR Conference in Boston.

Authors:  Thomas Graf
Journal:  Stem Cell Reports       Date:  2017-10-10       Impact factor: 7.765

6.  The aging skin microenvironment dictates stem cell behavior.

Authors:  Yejing Ge; Yuxuan Miao; Shiri Gur-Cohen; Nicholas Gomez; Hanseul Yang; Maria Nikolova; Lisa Polak; Yang Hu; Akanksha Verma; Olivier Elemento; James G Krueger; Elaine Fuchs
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-24       Impact factor: 11.205

7.  Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

Authors:  Aditi Qamra; Tsz Wai Chu; Mélanie Criqui; Monika Sharma; Julissa Tsao; Danielle A Henry; Dalia Barsyte-Lovejoy; Cheryl H Arrowsmith; Neil Winegarden; Mathieu Lupien; Lea Harrington
Journal:  Elife       Date:  2020-04-16       Impact factor: 8.140

Review 8.  Stem Cell DNA Damage and Genome Mutation in the Context of Aging and Cancer Initiation.

Authors:  Lara Al Zouabi; Allison J Bardin
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-10-01       Impact factor: 9.708

9.  Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells.

Authors:  Margarita Pustovalova; Тatiana A Astrelina; Anna Grekhova; Natalia Vorobyeva; Anastasia Tsvetkova; Taisia Blokhina; Victoria Nikitina; Yulia Suchkova; Daria Usupzhanova; Vitalyi Brunchukov; Irina Kobzeva; Тatiana Karaseva; Ivan V Ozerov; Aleksandr Samoylov; Andrey Bushmanov; Sergey Leonov; Evgeny Izumchenko; Alex Zhavoronkov; Dmitry Klokov; Andreyan N Osipov
Journal:  Aging (Albany NY)       Date:  2017-11-21       Impact factor: 5.682

10.  Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response.

Authors:  James C Jiang; Stefan W Stumpferl; S Michal Jazwinski
Journal:  Biogerontology       Date:  2018-10-08       Impact factor: 4.277
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