Literature DB >> 28093593

Self-assembled 4-(1,2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks.

Gaia Fumagalli1, Michael S Christodoulou1, Benedetta Riva2, Inigo Revuelta1, Cristina Marucci1, Veronica Collico2, Davide Prosperi2, Sergio Riva3, Dario Perdicchia1, Ivan Bassanini4, Aida García-Argáez5, Lisa Dalla Via6, Daniele Passarella1.   

Abstract

The ability of 4-(1,2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. The conjugation of this moiety with aloin or podophyllotoxin resulted in spherical nanoparticles that were characterized by Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM) and NanoSight technology. A preliminary biological evaluation on two cancer cell lines is reported.

Entities:  

Year:  2017        PMID： 28093593     DOI： 10.1039/c6ob02591a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance.

Authors:  Gaia Fumagalli; Giulia Giorgi; Máté Vágvölgyi; Eleonora Colombo; Michael S Christodoulou; Veronica Collico; Davide Prosperi; Franco Dosio; Attila Hunyadi; Monica Montopoli; Mariafrancesca Hyeraci; Alessandra Silvani; Giordano Lesma; Lisa Dalla Via; Daniele Passarella
Journal:  ACS Med Chem Lett       Date:  2018-04-17       Impact factor: 4.345

2.  Heteronanoparticles by self-Assembly of Doxorubicin and Cyclopamine Conjugates.

Authors:  Gaia Fumagalli; Barbara Stella; Ievgenia Pastushenko; Francesca Ricci; Michael S Christodoulou; Giovanna Damia; Davide Mazza; Silvia Arpicco; Clelia Giannini; Lavinia Morosi; Franco Dosio; Panagiota A Sotiropoulou; Daniele Passarella
Journal:  ACS Med Chem Lett       Date:  2017-08-01       Impact factor: 4.345

3.  New Class of Betulinic Acid-Based Nanoassemblies of Cabazitaxel, Podophyllotoxin, and Thiocolchicine.

Authors:  Eleonora Colombo; Laura Polito; Michele Biocotino; Paola Marzullo; Mariafrancesca Hyeraci; Lisa Dalla Via; Daniele Passarella
Journal:  ACS Med Chem Lett       Date:  2020-02-28       Impact factor: 4.345

4.  Self-assembling Releasable Thiocolchicine-Diphenylbutenylaniline Conjugates.

Authors:  Gaia Fumagalli; Laura Polito; Eleonora Colombo; Francesca Foschi; Michael S Christodoulou; Francesco Galeotti; Dario Perdicchia; Ivan Bassanini; Sergio Riva; Pierfausto Seneci; Aída García-Argáez; Lisa Dalla Via; Daniele Passarella
Journal:  ACS Med Chem Lett       Date:  2019-01-04       Impact factor: 4.345

5.  Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers.

Authors:  Eleonora Colombo; Michele Biocotino; Giulia Frapporti; Pietro Randazzo; Michael S Christodoulou; Giovanni Piccoli; Laura Polito; Pierfausto Seneci; Daniele Passarella
Journal:  Pharmaceutics       Date:  2019-08-20       Impact factor: 6.321
  5 in total

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