Literature DB >> 28075335

Towards standardization of x-ray beam filters in digital mammography and digital breast tomosynthesis: Monte Carlo simulations and analytical modelling.

Suman Shrestha1, Srinivasan Vedantham, Andrew Karellas.   

Abstract

In digital breast tomosynthesis and digital mammography, the x-ray beam filter material and thickness vary between systems. Replacing K-edge filters with Al was investigated with the intent to reduce exposure duration and to simplify system design. Tungsten target x-ray spectra were simulated with K-edge filters (50 µm Rh; 50 µm Ag) and Al filters of varying thickness. Monte Carlo simulations were conducted to quantify the x-ray scatter from various filters alone, scatter-to-primary ratio (SPR) with compressed breasts, and to determine the radiation dose to the breast. These data were used to analytically compute the signal-difference-to-noise ratio (SDNR) at unit (1 mGy) mean glandular dose (MGD) for W/Rh and W/Ag spectra. At SDNR matched between K-edge and Al filtered spectra, the reductions in exposure duration and MGD were quantified for three strategies: (i) fixed Al thickness and matched tube potential in kilovolts (kV); (ii) fixed Al thickness and varying the kV to match the half-value layer (HVL) between Al and K-edge filtered spectra; and, (iii) matched kV and varying the Al thickness to match the HVL between Al and K-edge filtered spectra. Monte Carlo simulations indicate that the SPR with and without the breast were not different between Al and K-edge filters. Modelling for fixed Al thickness (700 µm) and kV matched to K-edge filtered spectra, identical SDNR was achieved with 37-57% reduction in exposure duration and with 2-20% reduction in MGD, depending on breast thickness. Modelling for fixed Al thickness (700 µm) and HVL matched by increasing the kV over (0,4) range, identical SDNR was achieved with 62-65% decrease in exposure duration and with 2-24% reduction in MGD, depending on breast thickness. For kV and HVL matched to K-edge filtered spectra by varying Al filter thickness over (700, 880) µm range, identical SDNR was achieved with 23-56% reduction in exposure duration and 2-20% reduction in MGD, depending on breast thickness. These simulations indicate that increased fluence with Al filter of fixed or variable thickness substantially decreases exposure duration while providing for similar image quality with moderate reduction in MGD.

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Year:  2017        PMID: 28075335      PMCID: PMC5384796          DOI: 10.1088/1361-6560/aa58c8

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  38 in total

1.  Glandular breast dose for monoenergetic and high-energy X-ray beams: Monte Carlo assessment.

Authors:  J M Boone
Journal:  Radiology       Date:  1999-10       Impact factor: 11.105

2.  Additional factors for the estimation of mean glandular breast dose using the UK mammography dosimetry protocol.

Authors:  D R Dance; C L Skinner; K C Young; J R Beckett; C J Kotre
Journal:  Phys Med Biol       Date:  2000-11       Impact factor: 3.609

3.  Optimization of x-ray spectra in digital mammography through Monte Carlo simulations.

Authors:  D M Cunha; A Tomal; M E Poletti
Journal:  Phys Med Biol       Date:  2012-03-16       Impact factor: 3.609

4.  Digital Breast Tomosynthesis: State of the Art.

Authors:  Srinivasan Vedantham; Andrew Karellas; Gopal R Vijayaraghavan; Daniel B Kopans
Journal:  Radiology       Date:  2015-12       Impact factor: 11.105

5.  X-ray spectrum optimization of full-field digital mammography: simulation and phantom study.

Authors:  Philipp Bernhardt; Thomas Mertelmeier; Martin Hoheisel
Journal:  Med Phys       Date:  2006-11       Impact factor: 4.071

6.  Experimental investigation on the choice of the tungsten/rhodium anode/filter combination for an amorphous selenium-based digital mammography system.

Authors:  Paula Toroi; Federica Zanca; Kenneth C Young; Chantal van Ongeval; Guy Marchal; Hilde Bosmans
Journal:  Eur Radiol       Date:  2007-02-01       Impact factor: 5.315

7.  Scatter radiation in digital tomosynthesis of the breast.

Authors:  Ioannis Sechopoulos; Sankararaman Suryanarayanan; Srinivasan Vedantham; Carl J D'Orsi; Andrew Karellas
Journal:  Med Phys       Date:  2007-02       Impact factor: 4.071

8.  The myth of the 50-50 breast.

Authors:  M J Yaffe; J M Boone; N Packard; O Alonzo-Proulx; S Y Huang; C L Peressotti; A Al-Mayah; K Brock
Journal:  Med Phys       Date:  2009-12       Impact factor: 4.071

9.  A model for optimization of spectral shape in digital mammography.

Authors:  R Fahrig; M J Yaffe
Journal:  Med Phys       Date:  1994-09       Impact factor: 4.071

10.  Technical note: Skin thickness measurements using high-resolution flat-panel cone-beam dedicated breast CT.

Authors:  Linxi Shi; Srinivasan Vedantham; Andrew Karellas; Avice M O'Connell
Journal:  Med Phys       Date:  2013-03       Impact factor: 4.071

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  1 in total

1.  A prototype Multi-X-ray-source array (MXA) for digital breast tomosynthesis.

Authors:  Amy E Becker; Andrew M Hernandez; John M Boone; Paul R Schwoebel
Journal:  Phys Med Biol       Date:  2020-12-18       Impact factor: 3.609

  1 in total

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