Literature DB >> 28052607

OPTN/SRTR 2015 Annual Data Report: Lung.

M Valapour1,2, M A Skeans1, J M Smith1,3, L B Edwards4,5, W S Cherikh4,5, K Uccellini4,5, A K Israni1,6,7, J J Snyder1,6, B L Kasiske1,7.   

Abstract

In 2015, 2409 active candidates aged 12 years or older were added to the lung transplant waiting list; 2072 transplants were performed, the most of any year. The median waiting time for candidates listed in 2015 was 3.4 months; the shortest waiting time was for diagnosis group D. Despite the highest recorded transplant rate of 157 per 100 waitlist years, waitlist mortality continued a steady decade-long rise to a high of 16.5 deaths per 100 waitlist years. Measures of short- and long-term survival showed no trend toward improved overall survival in the past 5 years, except that 6-month death rates decreased from 9.4% in 2005 to 7.9% in 2014. At 5 years posttransplant, 55.5% of recipients remained alive. In 2015, 23 new child (ages 0-11 years) candidates were added to the list; 17 transplants were performed. Incidence of death was 6.1% at 6 months and 8.2% at 1 year for transplants in 2013-2014. Important policy changes will affect access to transplant. In February 2015, OPTN implemented a comprehensive revision of the lung allocation score to better reflect mortality risk. Broader geographic sharing of donor lungs for pediatric candidates and allowance for selected transplants across blood types for candidates aged younger than 2 years have been approved and are expected to improve pediatric access to transplant. The impact of these changes on lung transplant trends will be observed in the coming years. .

Entities:  

Keywords:  End-stage lung disease; lung allocation score; lung transplant; organ allocation; transplant outcomes

Mesh:

Substances:

Year:  2017        PMID: 28052607     DOI: 10.1111/ajt.14129

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  41 in total

Review 1.  New frontiers in immunosuppression.

Authors:  Luke J Benvenuto; Michaela R Anderson; Selim M Arcasoy
Journal:  J Thorac Dis       Date:  2018-05       Impact factor: 2.895

2.  Association of pretransplant and posttransplant program ratings with candidate mortality after listing.

Authors:  Andrew Wey; Sally K Gustafson; Nicholas Salkowski; Bertram L Kasiske; Melissa Skeans; Cory R Schaffhausen; Ajay K Israni; Jon J Snyder
Journal:  Am J Transplant       Date:  2018-08-21       Impact factor: 8.086

3.  Variability in donor organ offer acceptance and lung transplantation survival.

Authors:  Michael S Mulvihill; Hui J Lee; Jeremy Weber; Ashley Y Choi; Morgan L Cox; Babatunde A Yerokun; Muath A Bishawi; Jacob Klapper; Maragatha Kuchibhatla; Matthew G Hartwig
Journal:  J Heart Lung Transplant       Date:  2020-01-21       Impact factor: 10.247

4.  Contemporary Issues in Lung Transplant Allocation Practices.

Authors:  Wayne M Tsuang
Journal:  Curr Transplant Rep       Date:  2017-07-21

Review 5.  Pharmacologic Protection of Mitochondrial DNA Integrity May Afford a New Strategy for Suppressing Lung Ischemia-Reperfusion Injury.

Authors:  Yong B Tan; Sujata Mulekar; Olena Gorodnya; Michael J Weyant; Martin R Zamora; Jon D Simmons; Tiago Machuka; Mark N Gillespie
Journal:  Ann Am Thorac Soc       Date:  2017-09

6.  Heart and lung organ offer acceptance practices of transplant programs are associated with waitlist mortality and organ yield.

Authors:  Andrew Wey; Maryam Valapour; Melissa A Skeans; Nicholas Salkowski; Monica Colvin; Bertram L Kasiske; Ajay K Israni; Jon J Snyder
Journal:  Am J Transplant       Date:  2018-05-09       Impact factor: 8.086

Review 7.  Breathing lung transplantation with the Organ Care System (OCS) Lung: lessons learned and future implications.

Authors:  William Lightle; Daoud Daoud; Gabriel Loor
Journal:  J Thorac Dis       Date:  2019-09       Impact factor: 2.895

8.  Chest computed tomography imaging improves potential lung donor assessment.

Authors:  Jason M Gauthier; Andrew J Bierhals; Jingxia Liu; Keki R Balsara; Christine Frederiksen; Emily Gremminger; Ramsey R Hachem; Chad A Witt; Elbert P Trulock; Derek E Byers; Roger D Yusen; Patrick R Aguilar; Gary Marklin; Ruben G Nava; Benjamin D Kozower; Michael K Pasque; Bryan F Meyers; G Alexander Patterson; Daniel Kreisel; Varun Puri
Journal:  J Thorac Cardiovasc Surg       Date:  2018-11-24       Impact factor: 5.209

9.  Implications of declining donor offers with increased risk of disease transmission on waiting list survival in lung transplantation.

Authors:  Morgan L Cox; Michael S Mulvihill; Ashley Y Choi; Muath Bishawi; Asishana A Osho; John C Haney; Mani Daneshmand; Jacob A Klapper; Cameron R Wolfe; Matthew Hartwig
Journal:  J Heart Lung Transplant       Date:  2018-12-21       Impact factor: 10.247

10.  A novel patient-centered "intention-to-treat" metric of U.S. lung transplant center performance.

Authors:  Dawn A Maldonado; Arindam RoyChoudhury; David J Lederer
Journal:  Am J Transplant       Date:  2017-09-26       Impact factor: 8.086

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