| Literature DB >> 30040191 |
Andrew Wey1, Sally K Gustafson1, Nicholas Salkowski1, Bertram L Kasiske1,2, Melissa Skeans1, Cory R Schaffhausen2, Ajay K Israni1,2,3, Jon J Snyder1,3.
Abstract
The Scientific Registry of Transplant Recipients (SRTR) is responsible for understandable reporting of program metrics, including transplant rate, waitlist mortality, and posttransplant outcomes. SRTR developed five-tier systems for each metric to improve accessibility for the public. We investigated the associations of the five-tier assignments at listing with all-cause candidate mortality after listing, for candidates listed July 12, 2011-June 16, 2014. Transplant rate evaluations with one additional tier were associated with lower mortality after listing in kidney (hazard ratio [HR], 0.93 0.950.97 ), liver (HR, 0.87 0.900.92 ), and heart (HR, 0.92 0.961.00 ) transplantation. For lung transplant patients, mortality after listing was highest at programs with above- and below-average transplant rates and lowest at programs with average transplant rates, suggesting that aggressive acceptance behavior may not always provide a survival benefit. Waitlist mortality evaluations with one additional tier were associated with lower mortality after listing in kidney (HR, 0.94 0.960.99 ) transplantation, and posttransplant graft survival evaluations with one additional tier were associated with lower mortality after listing in lung (HR, 0.90 0.940.98 ) transplantation. Transplant rate typically had the strongest association with mortality after listing, but the strength of associations differed by organ.Entities:
Keywords: Scientific Registry for Transplant Recipients (SRTR); health services and outcomes research; organ transplantation in general; statistics
Mesh:
Year: 2018 PMID: 30040191 PMCID: PMC6837730 DOI: 10.1111/ajt.15032
Source DB: PubMed Journal: Am J Transplant ISSN: 1600-6135 Impact factor: 8.086