Literature DB >> 27999445

Identification of new geldanamycin derivatives from unexplored microbial culture extracts using a MS/MS library.

Jae Kyoung Lee1,2, Jae-Hyuk Jang1, Dong-Jin Park3, Chang-Jin Kim3, Jong Seog Ahn1, Bang Yeon Hwang2, Young-Soo Hong1.   

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Year:  2016        PMID： 27999445     DOI： 10.1038/ja.2016.143

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


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  20 in total

1.  Discovery of novel ansamycins possessing potent inhibitory activity in a cell-based oncostatin M signalling assay.

Authors:  P Stead; S Latif; A P Blackaby; P J Sidebottom; A Deakin; N L Taylor; P Life; J Spaull; F Burrell; R Jones; J Lewis; I Davidson; T Mander
Journal:  J Antibiot (Tokyo)       Date:  2000-07       Impact factor: 2.649

2.  Dereplication of microbial natural products by LC-DAD-TOFMS.

Authors:  Kristian F Nielsen; Maria Månsson; Christian Rank; Jens Christian Frisvad; Thomas O Larsen
Journal:  J Nat Prod       Date:  2011-10-25       Impact factor: 4.050

3.  Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety.

Authors:  Dongho Lee; Kyeong Lee; Xing Fu Cai; Nguyen Tien Dat; Shanthaveerappa K Boovanahalli; Mijeoung Lee; Jin Chul Shin; Woncheol Kim; Jae Kap Jeong; Jong Suk Lee; Choong-Hwan Lee; Jeong-Hyung Lee; Young-Soo Hong; Jung Joon Lee
Journal:  Chembiochem       Date:  2006-02       Impact factor: 3.164

4.  Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring.

Authors:  Woncheol Kim; Jong Suk Lee; Dongho Lee; Xing Fu Cai; Jin Chul Shin; Kyeong Lee; Choong-Hwan Lee; Sangryeol Ryu; Sang-Gi Paik; Jung Joon Lee; Young-Soo Hong
Journal:  Chembiochem       Date:  2007-09-03       Impact factor: 3.164

5.  Secondary metabolomics: natural products mass spectrometry goes global.

Authors:  Roland D Kersten; Pieter C Dorrestein
Journal:  ACS Chem Biol       Date:  2009-08-21       Impact factor: 5.100

Review 6.  Antibiotics in the clinical pipeline in 2011.

Authors:  Mark S Butler; Matthew A Cooper
Journal:  J Antibiot (Tokyo)       Date:  2011-05-18       Impact factor: 2.649

7.  Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin.

Authors:  Young-Soo Hong; Dongho Lee; Woncheol Kim; Jae-Kap Jeong; Chun-Gyu Kim; Jae Kyung Sohng; Jeong-Hyung Lee; Sang-Gi Paik; Jung Joon Lee
Journal:  J Am Chem Soc       Date:  2004-09-15       Impact factor: 15.419

Review 8.  Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy.

Authors:  Jana Franke; Simone Eichner; Carsten Zeilinger; Andreas Kirschning
Journal:  Nat Prod Rep       Date:  2013-08-12       Impact factor: 13.423

9.  Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds.

Authors:  Joshua J Kellogg; Daniel A Todd; Joseph M Egan; Huzefa A Raja; Nicholas H Oberlies; Olav M Kvalheim; Nadja B Cech
Journal:  J Nat Prod       Date:  2016-02-03       Impact factor: 4.050

10.  Rational biosynthetic engineering for optimization of geldanamycin analogues.

Authors:  Woncheol Kim; Dongho Lee; Seong Su Hong; Zhu Na; Jin Chul Shin; Su Heun Roh; Cheng-Zhu Wu; Oksik Choi; Kyeong Lee; Yue-Mao Shen; Sang-Gi Paik; Jung Joon Lee; Young-Soo Hong
Journal:  Chembiochem       Date:  2009-05-04       Impact factor: 3.164
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  1 in total

1.  Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen Streptomyces sp. 11-1-2.

Authors:  Gustavo A Díaz-Cruz; Jingyu Liu; Kapil Tahlan; Dawn R D Bignell
Journal:  Microbiol Spectr       Date:  2022-02-28
  1 in total

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