Literature DB >> 279922

Units of transcription for cytoplasmic RNA in mouse myeloma cells.

R Giorno, W Sauerbier.   

Abstract

The size of transcription units for several of the abundant cytoplasmic mRNA species in mouse myeloma cells has been analyzed by the ultraviolet light mapping technique. Inactivation kinetics and target size analyses for production of the predominant RNA species indicate that the mRNAs originate in precursor molecules that are 2--14 times larger than the mature mRNA. This estimate of the size of the transcription unit may be a minimum one since it would not take into account promoter-distal sequences if these were not necessary for processing of the mRNA precursor.

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Year:  1978        PMID： 279922      PMCID： PMC336117          DOI： 10.1073/pnas.75.9.4374

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  A method for the detection of RNA-DNA complexes.

Authors:  A P NYGAARD; B D HALL
Journal:  Biochem Biophys Res Commun       Date:  1963-07-18       Impact factor: 3.575

2.  A radiological analysis of the transcription units for heterogeneous nuclear RNA in cultured murine cells.

Authors:  R Giorno; W Sauerbier
Journal:  Cell       Date:  1976-12       Impact factor: 41.582

3.  A precursor of globin messenger RNA.

Authors:  J Ross
Journal:  J Mol Biol       Date:  1976-09-15       Impact factor: 5.469

4.  Globin RNA precursor molecules: biosynthesis and process in erythroid cells.

Authors:  R N Bastos; H Aviv
Journal:  Cell       Date:  1977-07       Impact factor: 41.582

5.  Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.

Authors:  C Brack; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

6.  Immunoglobulin light chain mRNA is processed from large nuclear RNA.

Authors:  M Gilmore-Hebert; R Wall
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

7.  Evidence for noncontiguous variable and constant region genes in both germ line and myeloma DNA.

Authors:  T H Rabbitts; A Forster
Journal:  Cell       Date:  1978-02       Impact factor: 41.582

8.  Purification of globin messenger RNA from dimethylsulfoxide-induced Friend cells and detection of a putative globin messenger RNA precursor.

Authors:  P J Curtis; C Weissmann
Journal:  J Mol Biol       Date:  1976-10-05       Impact factor: 5.469

9.  The rabbit beta-globin gene contains a large large insert in the coding sequence.

Authors:  A J Jeffreys; R A Flavell
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

10.  The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

Authors:  S M Tilghman; P J Curtis; D C Tiemeier; P Leder; C Weissmann
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205
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  5 in total

1.  An effect of ultraviolet light on RNA and protein synthesis in nondividing human diploid fibroblasts.

Authors:  G J Kantor; D R Hull
Journal:  Biophys J       Date:  1979-09       Impact factor: 4.033

2.  Rat growth hormone gene: intervening sequences separate the mRNA regions.

Authors:  H Soreq; M Harpold; R Evans; J E Darnell; F C Bancroft
Journal:  Nucleic Acids Res       Date:  1979-06-11       Impact factor: 16.971

3.  Large heterogeneous nuclear ribonucleic acid has three times as many 5' caps as polyadenylic acid segments, and most caps do not enter polyribosomes.

Authors:  M Salditt-Georgieff; M M Harpold; M C Wilson; J E Darnell
Journal:  Mol Cell Biol       Date:  1981-02       Impact factor: 4.272

4.  Chinese hamster polyadenylated messenger ribonucleic acid: relationship to non-polyadenylated sequences and relative conservation during messenger ribonucleic acid processing.

Authors:  M M Harpold; M C Wilson; J E Darnell
Journal:  Mol Cell Biol       Date:  1981-02       Impact factor: 4.272

5.  Abortive transcription products of vaccinia virus are guanylylated, methylated, and polyadenylylated.

Authors:  A Gershowitz; B Moss
Journal:  J Virol       Date:  1979-09       Impact factor: 5.103
  5 in total

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