Literature DB >> 461195

Rat growth hormone gene: intervening sequences separate the mRNA regions.

H Soreq, M Harpold, R Evans, J E Darnell, F C Bancroft.   

Abstract

Rat genomic DNA was digested with various restriction endonucleases, separated by gel electrophoresis and hybridized to 125 I-labeled mRNA for the precursor protein to growth hormone. Restriction sites were found within the genomic DNA that were not found in the previously reported DNA sequence corresponding to the mRNA (19). It appears that the gene for growth hormone contains intervening sequences separating the DNA regions that specify mRNA sequences.

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Year:  1979        PMID： 461195      PMCID： PMC327866          DOI： 10.1093/nar/6.7.2471

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  22 in total

1.  Pregrowth hormone messenger RNA: glucocorticoid induction and identification in rat pituitary cells.

Authors:  R J Tushinski; P M Sussman; L Y Yu; F C Bancroft
Journal:  Proc Natl Acad Sci U S A       Date:  1977-06       Impact factor: 11.205

2.  The ovalbumin gene: structural sequences in native chicken DNA are not contiguous.

Authors:  E C Lai; S L Woo; A Dugaiczyk; J F Catterall; B W O'Malley
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

3.  Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

Authors:  S M Tilghman; D C Tiemeier; J G Seidman; B M Peterlin; M Sullivan; J V Maizel; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

4.  Units of transcription for cytoplasmic RNA in mouse myeloma cells.

Authors:  R Giorno; W Sauerbier
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

5.  Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence.

Authors:  M M Harpold; P R Dobner; R M Evans; F C Bancroft
Journal:  Nucleic Acids Res       Date:  1978-06       Impact factor: 16.971

6.  Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone.

Authors:  P H Seeburg; J Shine; J A Martial; J D Baxter; H M Goodman
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

7.  Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.

Authors:  C Brack; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

8.  Immunoglobulin light chain mRNA is processed from large nuclear RNA.

Authors:  M Gilmore-Hebert; R Wall
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

9.  Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

Authors:  S Tonegawa; A M Maxam; R Tizard; O Bernard; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

10.  Evidence from UV transcription mapping in HeLa cells that heterogeneous nuclear RNA is the messenger RNA precursor.

Authors:  S Goldberg; H Schwartz; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205
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  2 in total

Review 1.  Sequence organization of animal nuclear DNA.

Authors:  J Schmidtke; J T Epplen
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

2.  Structural organization of a 17 KB segment of the alpha 2 collagen gene: evaluation by R loop mapping.

Authors:  M P Schafer; C D Boyd; P Tolstoshev; R G Crystal
Journal:  Nucleic Acids Res       Date:  1980-05-24       Impact factor: 16.971
  2 in total

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