Sara L Zettervall1, Marc L Schermerhorn2, Peter A Soden1, John C McCallum1, Katie E Shean1, Sarah E Deery1, A James O'Malley3, Bruce Landon4. 1. Department of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, Mass. 2. Department of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, Mass. Electronic address: mscherm@bidmc.harvard.edu. 3. Department of Biomedical Data Science and The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH. 4. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Mass; Department of Health Care Policy, Harvard Medical School, Boston, Mass.
Abstract
BACKGROUND: Higher hospital and surgeon volumes are independently associated with improved mortality after open repair of abdominal aortic aneurysms (AAAs) in the era before endovascular AAA repair (EVAR). The effects of both surgeon and hospital volume on mortality after EVAR and open repair in the current era are less well defined. METHODS: We studied Medicare beneficiaries who underwent elective AAA repair from 2001 to 2008. Volume was measured by procedure type during the 1-year period preceding each procedure and was further categorized into quintiles of volume for surgeon and hospital. Multilevel logistic regression models were used to evaluate the effect of surgeon volume, accounting for hospital volume, on mortality after adjusting for patient demographic and comorbid conditions as well as the analogous effect of hospital volume adjusting for surgeon volume. The multilevel models included random effects for surgeon and hospital to account for the clustering of multiple patients within the same surgeon and within the same hospital. RESULTS: We studied 122,495 patients who underwent AAA repair (open: 45,451; EVAR: 77,044). After EVAR, perioperative mortality did not differ by surgeon volume (quintile 1 [0-6 EVARs]: 1.8%; quintile 5 [28-151 EVARs]: 1.6%; P = .29), but decreased with greater hospital volume (quintile 1 [0-9 EVARs]: 1.9%; quintile 5 [49-198 EVARs]: 1.4%; P < .01). After open repair, perioperative mortality decreased with both higher surgeon volume (quintile 1 [0-3 open repairs]: 6.4%; quintile 5 [14-62 open repairs]: 3.8%; P < .01) and hospital volume (quintile 1 [0-5 open repairs]: 6.3%; quintile 5 [14-62 open repairs]: 3.8%; P < .01). After adjustment for other predictors, surgeon volume was not associated with perioperative mortality after EVAR (odds ratio [OR], 0.9; 95% confidence interval [CI], 0.7-1.1); however, hospital volume was associated with higher perioperative mortality (quintile 1: OR, 1.5; 95% CI, 1.2-1.9; quintile 2: OR, 1.3; 95% CI, 1.02-1.6; and quintile 3: OR, 1.2; 95% CI, 1.01-1.5, compared with 5). After open repair, higher surgeon volume was also associated with lower mortality (quintile 1: OR, 1.5; 95% CI, 1.3-1.8; quintile 2: OR, 1.3; 95% CI, 1.1-1.6; and quintile 3: OR, 1.2; 95% CI, 1.1-1.4, compared with 5). Risk of mortality also was higher for patients treated at lower-volume hospitals (quintile 1: OR, 1.3; 95% CI, 1.1-1.5; quintile 2: OR, 1.3; 95% CI, 1.1-1.5; and quintile 3: OR, 1.2; 95% CI, 1.1-1.4, compared with 5). CONCLUSIONS: After EVAR, hospital volume is minimally associated with perioperative mortality, with no such association for surgeon volume. After open AAA repair, surgeon and hospital volume are both strongly associated with mortality. These findings suggest that open surgery should be concentrated in hospitals and surgeons with high volume.
BACKGROUND: Higher hospital and surgeon volumes are independently associated with improved mortality after open repair of abdominal aortic aneurysms (AAAs) in the era before endovascular AAA repair (EVAR). The effects of both surgeon and hospital volume on mortality after EVAR and open repair in the current era are less well defined. METHODS: We studied Medicare beneficiaries who underwent elective AAA repair from 2001 to 2008. Volume was measured by procedure type during the 1-year period preceding each procedure and was further categorized into quintiles of volume for surgeon and hospital. Multilevel logistic regression models were used to evaluate the effect of surgeon volume, accounting for hospital volume, on mortality after adjusting for patient demographic and comorbid conditions as well as the analogous effect of hospital volume adjusting for surgeon volume. The multilevel models included random effects for surgeon and hospital to account for the clustering of multiple patients within the same surgeon and within the same hospital. RESULTS: We studied 122,495 patients who underwent AAA repair (open: 45,451; EVAR: 77,044). After EVAR, perioperative mortality did not differ by surgeon volume (quintile 1 [0-6 EVARs]: 1.8%; quintile 5 [28-151 EVARs]: 1.6%; P = .29), but decreased with greater hospital volume (quintile 1 [0-9 EVARs]: 1.9%; quintile 5 [49-198 EVARs]: 1.4%; P < .01). After open repair, perioperative mortality decreased with both higher surgeon volume (quintile 1 [0-3 open repairs]: 6.4%; quintile 5 [14-62 open repairs]: 3.8%; P < .01) and hospital volume (quintile 1 [0-5 open repairs]: 6.3%; quintile 5 [14-62 open repairs]: 3.8%; P < .01). After adjustment for other predictors, surgeon volume was not associated with perioperative mortality after EVAR (odds ratio [OR], 0.9; 95% confidence interval [CI], 0.7-1.1); however, hospital volume was associated with higher perioperative mortality (quintile 1: OR, 1.5; 95% CI, 1.2-1.9; quintile 2: OR, 1.3; 95% CI, 1.02-1.6; and quintile 3: OR, 1.2; 95% CI, 1.01-1.5, compared with 5). After open repair, higher surgeon volume was also associated with lower mortality (quintile 1: OR, 1.5; 95% CI, 1.3-1.8; quintile 2: OR, 1.3; 95% CI, 1.1-1.6; and quintile 3: OR, 1.2; 95% CI, 1.1-1.4, compared with 5). Risk of mortality also was higher for patients treated at lower-volume hospitals (quintile 1: OR, 1.3; 95% CI, 1.1-1.5; quintile 2: OR, 1.3; 95% CI, 1.1-1.5; and quintile 3: OR, 1.2; 95% CI, 1.1-1.4, compared with 5). CONCLUSIONS: After EVAR, hospital volume is minimally associated with perioperative mortality, with no such association for surgeon volume. After open AAA repair, surgeon and hospital volume are both strongly associated with mortality. These findings suggest that open surgery should be concentrated in hospitals and surgeons with high volume.
Authors: Elliot L Chaikof; David C Brewster; Ronald L Dalman; Michel S Makaroun; Karl A Illig; Gregorio A Sicard; Carlos H Timaran; Gilbert R Upchurch; Frank J Veith Journal: J Vasc Surg Date: 2009-10 Impact factor: 4.268
Authors: Bruce E Landon; A James O'Malley; Kristina Giles; Philip Cotterill; Marc L Schermerhorn Journal: Circulation Date: 2010-09-13 Impact factor: 29.690
Authors: N E Marlow; B Barraclough; N A Collier; I C Dickinson; J Fawcett; J C Graham; G J Maddern Journal: Eur J Vasc Endovasc Surg Date: 2010-08-05 Impact factor: 7.069
Authors: Thomas F X O'Donnell; Virendra I Patel; Sarah E Deery; Chun Li; Nicholas J Swerdlow; Patric Liang; Adam W Beck; Marc L Schermerhorn Journal: J Vasc Surg Date: 2019-02-02 Impact factor: 4.268
Authors: Sarah E Deery; Thomas F X O'Donnell; Thomas C F Bodewes; Barbara A Dalebout; Alexander B Pothof; Katie E Shean; Jeremy D Darling; Marc L Schermerhorn Journal: J Vasc Surg Date: 2017-09-21 Impact factor: 4.268
Authors: Christina M Theodorou; Jamie E Anderson; Megan Brenner; Thomas M Scalea; Kenji Inaba; Jeremy Cannon; Mark Seamon; M Chance Spalding; Charles J Fox; Ernest E Moore; Joseph J DuBose; Joseph M Galante Journal: J Surg Res Date: 2020-04-17 Impact factor: 2.192
Authors: Sarah E Deery; Thomas F X O'Donnell; Katie E Shean; Jeremy D Darling; Peter A Soden; Kakra Hughes; Grace J Wang; Marc L Schermerhorn Journal: J Vasc Surg Date: 2017-10-23 Impact factor: 4.268
Authors: Sarah E Deery; Thomas F X O'Donnell; Sara L Zettervall; Jeremy D Darling; Katie E Shean; A James O'Malley; Bruce E Landon; Marc L Schermerhorn Journal: Eur J Vasc Endovasc Surg Date: 2018-03-31 Impact factor: 7.069