Xianchun Zeng1,2, Mladen Barbic3, Liangliang Chen2, Chunqi Qian2. 1. Department of Radiology, Guizhou Provincial People's Hospital, Guiyang, China. 2. Department of Radiology, Michigan State University, East Lansing, Michigan, USA. 3. Applied Physics and Instrumentation Group, Howard Huge Medical Institute, Janelia Research Campus, Ashburn, Virginia, USA.
Abstract
PURPOSE: To improve the imaging quality of vessel walls with an endoesophageal Wireless Amplified NMR Detector (WAND). METHODS: A cylindrically shaped double-frequency resonator has been constructed with a single metal wire that is self-connected by a pair of nonlinear capacitors. The double-frequency resonator can convert wirelessly provided pumping power into amplified MR signals. This compact design makes the detector easily insertable into a rodent esophagus. RESULTS: The detector has good longitudinal and axial symmetry. Compared to an external surface coil, the WAND can enhance detection sensitivity by at least 5 times, even when the distance separation between the region of interest and the detector's cylindrical surface is twice the detector's own radius. Such detection capability enables us to observe vessel walls near the aortic arch and carotid bifurcation with elevated sensitivity. CONCLUSION: A cylindrical MRI detector integrated with a wireless-powered amplifier has been developed as an endoesophageal detector to enhance detection sensitivity of vessel walls. This detector can greatly improve the imaging quality for vessel regions that are susceptible to atherosclerotic lesions. Magn Reson Med 78:2048-2054, 2017.
PURPOSE: To improve the imaging quality of vessel walls with an endoesophageal Wireless Amplified NMR Detector (WAND). METHODS: A cylindrically shaped double-frequency resonator has been constructed with a single metal wire that is self-connected by a pair of nonlinear capacitors. The double-frequency resonator can convert wirelessly provided pumping power into amplified MR signals. This compact design makes the detector easily insertable into a rodent esophagus. RESULTS: The detector has good longitudinal and axial symmetry. Compared to an external surface coil, the WAND can enhance detection sensitivity by at least 5 times, even when the distance separation between the region of interest and the detector's cylindrical surface is twice the detector's own radius. Such detection capability enables us to observe vessel walls near the aortic arch and carotid bifurcation with elevated sensitivity. CONCLUSION: A cylindrical MRI detector integrated with a wireless-powered amplifier has been developed as an endoesophageal detector to enhance detection sensitivity of vessel walls. This detector can greatly improve the imaging quality for vessel regions that are susceptible to atherosclerotic lesions. Magn Reson Med 78:2048-2054, 2017.
Authors: Chunqi Qian; Xin Yu; Nikorn Pothayee; Stephen Dodd; Nadia Bouraoud; Robert Star; Kevin Bennett; Alan Koretsky Journal: Am J Physiol Renal Physiol Date: 2014-09-03
Authors: Hunter R Underhill; Thomas S Hatsukami; Zahi A Fayad; Valentin Fuster; Chun Yuan Journal: Nat Rev Cardiol Date: 2010-01-26 Impact factor: 32.419