Literature DB >> 279009

Monoclonal antibodies against rabies virus produced by somatic cell hybridization: detection of antigenic variants.

T J Wiktor, H Koprowski.   

Abstract

Somatic cell hybrids (hybridomas) between mouse myeloma cells and spleen cells derived from BALB/c mice immunized with inactivated rabies vaccine were found to produce antibodies to rabies virus. Monoclonal antibodies with different specificities were obtained either from the mass culture directly after fusion or from clones derived from a single-cell cloning procedure. Several strains of fixed or street rabies virus were analyzed by virus neutralization procedures which demonstrated differences in their antigenic composition. Hybridoma antibodies were able to protect experimental animals from lethal rabies virus infection.

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Year:  1978        PMID： 279009      PMCID： PMC392904          DOI： 10.1073/pnas.75.8.3938

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  12 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  Repertoire of antiviral antibodies expressed by somatic cell hybrids.

Authors:  W Gerhard; C M Croce; D Lopes; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

3.  Role of host immune response in the development of either encephalitic or paralytic disease after experimental rabies infection in mice.

Authors:  Y Iwasaki; W Gerhard; H F Clark
Journal:  Infect Immun       Date:  1977-10       Impact factor: 3.441

4.  Antigenic properties of rabies virus components.

Authors:  T J Wiktor; E György; D Schlumberger; F Sokol; H Koprowski
Journal:  J Immunol       Date:  1973-01       Impact factor: 5.422

5.  Rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses.

Authors:  L G Schneider; B Dietzschold; R E Dierks; W Matthaeus; P J Enzmann; K Strohmaier
Journal:  J Virol       Date:  1973-05       Impact factor: 5.103

6.  Comparison of rabies virus strains by means of the plaque reduction test.

Authors:  T J Wiktor; H F Clark
Journal:  Ann Microbiol (Paris)       Date:  1973-03

7.  Immunogenicity of concentrated and purified rabies vaccine of tissue culture origin.

Authors:  T J Wiktor; F Sokol; E Kuwert; H Koprowski
Journal:  Proc Soc Exp Biol Med       Date:  1969-07

8.  Laboratory techniques in rabies: the NIH test for potency.

Authors:  E B Seligmann
Journal:  Monogr Ser World Health Organ       Date:  1973

9.  A rapid tissue culture test for determining rabies neutralizing antibody.

Authors:  J S Smith; P A Yager; G M Baer
Journal:  Monogr Ser World Health Organ       Date:  1973

10.  Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

Authors:  H Koprowski; W Gerhard; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205
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  44 in total

1.  Structural analysis of hepatitis B surface antigen by monoclonal antibodies.

Authors:  E Ben-Porath; J R Wands; R A Marciniak; M A Wong; L Hornstein; R Ryder; M Canlas; A Lingao; K J Isselbacher
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

2.  Development of monoclonal antibodies suitable for rabies virus antibody and antigen detection.

Authors:  Vishal Chander; R P Singh; P C Verma
Journal:  Indian J Virol       Date:  2012-09-26

3.  Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7.

Authors:  P A Offit; R D Shaw; H B Greenberg
Journal:  J Virol       Date:  1986-05       Impact factor: 5.103

4.  Antibodies to cell surface proteins redirect intracellular trafficking pathways.

Authors:  Christine A St Pierre; Deborah Leonard; Silvia Corvera; Evelyn A Kurt-Jones; Robert W Finberg
Journal:  Exp Mol Pathol       Date:  2011-07-23       Impact factor: 3.362

5.  In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes.

Authors:  T Aebischer; D Moskophidis; U H Rohrer; R M Zinkernagel; H Hengartner
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

6.  Genetic control of serum neutralizing-antibody response to rabies vaccination and survival after a rabies challenge infection in mice.

Authors:  J W Templeton; C Holmberg; T Garber; R M Sharp
Journal:  J Virol       Date:  1986-07       Impact factor: 5.103

7.  Typing of cytopathic and noncytopathic bovine viral diarrhea virus reference and Canadian field strains using a neutralizing monoclonal antibody.

Authors:  R Magar; H C Minocha; C Montpetit; P S Carman; J Lecomte
Journal:  Can J Vet Res       Date:  1988-01       Impact factor: 1.310

8.  Further studies on an improved haemagglutination inhibition test with higher sensitivity for rabies virus antibody.

Authors:  K Mifune; K Mannen; N Minamoto; Y T Arai
Journal:  Bull World Health Organ       Date:  1986       Impact factor: 9.408

9.  Morphologic appearance of inclusion bodies and their association with the antigenic composition of naturally occurring rabies viruses.

Authors:  K Loretu; D C Blenden; M J Torres-Anjel; F T Satalowich
Journal:  J Clin Microbiol       Date:  1988-02       Impact factor: 5.948

10.  Molecular mimicry: frequency of reactivity of monoclonal antiviral antibodies with normal tissues.

Authors:  J Srinivasappa; J Saegusa; B S Prabhakar; M K Gentry; M J Buchmeier; T J Wiktor; H Koprowski; M B Oldstone; A L Notkins
Journal:  J Virol       Date:  1986-01       Impact factor: 5.103
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