OBJECTIVE: To detect an in-stent restenosis, an invasive coronary angiography is commonly performed. Owing to the risk associated with this procedure, a non-invasive method to detect or exclude an in-stent restenosis is desirable. The purpose of this study was to evaluate the influence of cardiac motion on stent lumen visibility in a third-generation dual-source CT scanner (SOMATOM Force; Siemens Healthcare, Forchheim, Germany), employing a pulsatile heart model (CoroSim®; Mecora, Aachen, Germany). METHODS: 13 coronary stents with a diameter of 3.0 mm were implanted in plastic tubes filled with a contrast medium and then fixed onto the pulsatile phantom heart model. The scans were performed while the heart model mimicked the heartbeat. Coronary stents were scanned in an orientation parallel to the scanner z-axis. The evaluation of the stents was performed by employing a medium sharp convolution kernel optimized for vascular imaging. RESULTS: The mean visible stent lumen was reduced from 65.6 ± 5.7% for the stents at rest to 60.8 ± 4.4% for the stents in motion (p-value: <0.001). CONCLUSION: While the difference in lumen visibility between stents in motion and at rest was significant, the use of this third-generation dual-source CT scanner enabled a high stent lumen visibility under the influence of cardiac motion. Whether this translates into a clinical setting has to be evaluated in further patient studies. Advances in knowledge: The employed modern CT scanner enables a high stent lumen visibility even under the influence of cardiac motion, which is important to detect or exclude an in-stent restenosis.
OBJECTIVE: To detect an in-stent restenosis, an invasive coronary angiography is commonly performed. Owing to the risk associated with this procedure, a non-invasive method to detect or exclude an in-stent restenosis is desirable. The purpose of this study was to evaluate the influence of cardiac motion on stent lumen visibility in a third-generation dual-source CT scanner (SOMATOM Force; Siemens Healthcare, Forchheim, Germany), employing a pulsatile heart model (CoroSim®; Mecora, Aachen, Germany). METHODS: 13 coronary stents with a diameter of 3.0 mm were implanted in plastic tubes filled with a contrast medium and then fixed onto the pulsatile phantom heart model. The scans were performed while the heart model mimicked the heartbeat. Coronary stents were scanned in an orientation parallel to the scanner z-axis. The evaluation of the stents was performed by employing a medium sharp convolution kernel optimized for vascular imaging. RESULTS: The mean visible stent lumen was reduced from 65.6 ± 5.7% for the stents at rest to 60.8 ± 4.4% for the stents in motion (p-value: <0.001). CONCLUSION: While the difference in lumen visibility between stents in motion and at rest was significant, the use of this third-generation dual-source CT scanner enabled a high stent lumen visibility under the influence of cardiac motion. Whether this translates into a clinical setting has to be evaluated in further patient studies. Advances in knowledge: The employed modern CT scanner enables a high stent lumen visibility even under the influence of cardiac motion, which is important to detect or exclude an in-stent restenosis.
Authors: Amir A Mahabadi; Stephan Achenbach; Christof Burgstahler; Thorsten Dill; Roman Fischbach; Andreas Knez; Werner Moshage; Barbara M Richartz; Dieter Ropers; Stephen Schröder; Sigmund Silber; Stefan Möhlenkamp Journal: Radiology Date: 2010-12 Impact factor: 11.105
Authors: Harald Seifarth; Rainer Raupach; Stefan Schaller; Eva Maria Fallenberg; Thomas Flohr; Walter Heindel; Roman Fischbach; David Maintz Journal: Eur Radiol Date: 2005-02-12 Impact factor: 5.315
Authors: Harald Seifarth; Murat Ozgün; Rainer Raupach; Thomas Flohr; Walter Heindel; Roman Fischbach; David Maintz Journal: Invest Radiol Date: 2006-01 Impact factor: 6.016
Authors: Tobias Gassenmaier; Nils Petri; Thomas Allmendinger; Thomas Flohr; Andreas M Weng; Andreas S Kunz; Bernhard Petritsch; Wolfram Voelker; Thorsten A Bley Journal: Acad Radiol Date: 2016-05-25 Impact factor: 3.173
Authors: David Maintz; Harald Seifarth; Rainer Raupach; Thomas Flohr; Michael Rink; Torsten Sommer; Murat Ozgün; Walter Heindel; Roman Fischbach Journal: Eur Radiol Date: 2005-12-07 Impact factor: 5.315
Authors: George D Dangas; Bimmer E Claessen; Adriano Caixeta; Elias A Sanidas; Gary S Mintz; Roxana Mehran Journal: J Am Coll Cardiol Date: 2010-11-30 Impact factor: 24.094
Authors: Olivio F Donati; Matthias C Burg; Lotus Desbiolles; Christoph Karlo; Paul Stolzmann; Alexander Bunck; Stephan Baumueller; Borut Marincek; Harald Seifarth; Hatem Alkadhi; Sebastian Leschka; David Maintz Journal: Acad Radiol Date: 2010-11 Impact factor: 3.173
Authors: F Pugliese; A C Weustink; C Van Mieghem; F Alberghina; M Otsuka; W B Meijboom; N van Pelt; N R Mollet; F Cademartiri; G P Krestin; M G M Hunink; P J de Feyter Journal: Heart Date: 2007-09-19 Impact factor: 5.994