Literature DB >> 27764081

National Progress Toward Hepatitis C Elimination - Georgia, 2015-2016.

Lia Gvinjilia, Muazzam Nasrullah, David Sergeenko, Tengiz Tsertsvadze, George Kamkamidze, Maia Butsashvili, Amiran Gamkrelidze, Paata Imnadze, Valeri Kvaratskhelia, Nikoloz Chkhartishvili, Lali Sharvadze, Jan Drobeniuc, Liesl Hagan, John W Ward, Juliette Morgan, Francisco Averhoff.   

Abstract

The country of Georgia has a high prevalence of hepatitis C virus (HCV) infection, associated with exposures to HCV in health care settings with inadequate infection control and unsafe injections among persons who inject drugs (1). In April 2015, in collaboration with CDC and other partners, Georgia embarked on a program to eliminate HCV infection, subsequently defined as achieving a 90% reduction in prevalence by 2020. The initial phase of the program focused on providing HCV treatment to infected persons with advanced liver disease and at highest risk for HCV-associated morbidity and mortality. By April 27, 2016, a total of 27,392 HCV-infected persons registered for the program, 8,448 (30.8%) started treatment, and 5,850 patients (69.2%) completed HCV treatment. Among patients completing treatment who were eligible for posttreatment testing, 2,398 received polymerase chain reaction (PCR) testing for HCV at least 12 weeks after completion of treatment; 1,980 (82.6%) had no detectable virus, indicative of a sustained virologic response* (i.e., cure). Major challenges to achieving elimination remain, including the need to increase access to care and treatment services and implement a comprehensive approach to prevention and control of HCV infection. As a global leader in this effort, the Georgia HCV Elimination Program can help pave the way for other countries experiencing high rates of HCV infection to undertake similar initiatives.

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Year:  2016        PMID: 27764081     DOI: 10.15585/mmwr.mm6541a2

Source DB:  PubMed          Journal:  MMWR Morb Mortal Wkly Rep        ISSN: 0149-2195            Impact factor:   17.586


  29 in total

1.  HCV elimination - lessons learned from a small Eurasian country, Georgia.

Authors:  Muazzam Nasrullah; David Sergeenko; Amiran Gamkrelidze; Francisco Averhoff
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-07-26       Impact factor: 46.802

2.  Three Years of Progress Toward Achieving Hepatitis C Elimination in the Country of Georgia, April 2015-March 2018.

Authors:  Tengiz Tsertsvadze; Amiran Gamkrelidze; Nikoloz Chkhartishvili; Akaki Abutidze; Lali Sharvadze; Vakhtang Kerashvili; Maia Butsashvili; David Metreveli; Lia Gvinjilia; Shaun Shadaker; Muazzam Nasrullah; Ekaterine Adamia; Stefan Zeuzem; Nezam Afdhal; Sanjeev Arora; Karla Thornton; Beth Skaggs; Tinatin Kuchuloria; Maia Lagvilava; David Sergeenko; Francisco Averhoff
Journal:  Clin Infect Dis       Date:  2020-08-22       Impact factor: 9.079

3.  Implementing and scaling up HCV treatment services for people who inject drugs and other high risk groups in Ukraine: An evaluation of programmatic and treatment outcomes.

Authors:  Alyona Mazhnaya; Anna Meteliuk; Tetiana Barnard; Alexei Zelenev; Sergii Filippovych; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2017-08-12

4.  Hepatitis C care continuum and associated barriers among people who inject drugs in Chennai, India.

Authors:  Eshan U Patel; Sunil S Solomon; Allison M Mcfall; Aylur K Srikrishnan; Amrose Pradeep; Paneerselvam Nandagopal; Oliver Laeyendecker; Aaron A R Tobian; David L Thomas; Mark S Sulkowski; M Suresh Kumar; Shruti H Mehta
Journal:  Int J Drug Policy       Date:  2018-04-19

5.  Hepatitis C Treatment Cascade in a Federally Qualified Health Center.

Authors:  David M Hachey; John T Holmes; Nicki L Aubuchon-Endsley
Journal:  J Community Health       Date:  2020-04

Review 6.  Designing an HCV vaccine: a unique convergence of prevention and therapy?

Authors:  Christopher M Walker
Journal:  Curr Opin Virol       Date:  2017-05-25       Impact factor: 7.090

7.  Progress and challenges of a pioneering hepatitis C elimination program in the country of Georgia.

Authors:  Francisco Averhoff; Shaun Shadaker; Amiran Gamkrelidze; Tatia Kuchuloria; Lia Gvinjilia; Vladimer Getia; David Sergeenko; Maia Butsashvili; Tengiz Tsertsvadze; Lali Sharvadze; Jaba Zarkua; Beth Skaggs; Muazzam Nasrullah
Journal:  J Hepatol       Date:  2019-12-04       Impact factor: 25.083

8.  The burden and epidemiology of hepatitis B and hepatitis D in Georgia: findings from the national seroprevalence survey.

Authors:  A Kasradze; S Shadaker; T Kuchuloria; A Gamkrelidze; M Nasrullah; L Gvinjilia; D Baliashvili; N Chitadze; M Kodani; A Tejada-Strop; J Drobeniuc; L Hagan; J Morgan; P Imnadze; F Averhoff
Journal:  Public Health       Date:  2020-07-29       Impact factor: 2.427

Review 9.  The Elimination of Hepatitis C as a Public Health Threat.

Authors:  Margaret Hellard; Sophia E Schroeder; Alisa Pedrana; Joseph Doyle; Campbell Aitken
Journal:  Cold Spring Harb Perspect Med       Date:  2020-04-01       Impact factor: 6.915

10.  Importance and Contribution of Community, Social, and Healthcare Risk Factors for Hepatitis C Infection in Pakistan.

Authors:  Adam Trickey; Margaret T May; Charlotte Davies; Huma Qureshi; Saeed Hamid; Hassan Mahmood; Quaid Saeed; Matthew Hickman; Nancy Glass; Francisco Averhoff; Peter Vickerman
Journal:  Am J Trop Med Hyg       Date:  2017-10-12       Impact factor: 2.345

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