Literature DB >> 31512110

Hepatitis C Treatment Cascade in a Federally Qualified Health Center.

David M Hachey1, John T Holmes2, Nicki L Aubuchon-Endsley3.   

Abstract

Hepatitis C (HCV) care cascades have been described in diverse clinical settings, patient populations and countries, highlighting the steps in HCV care where improvements can be made and resources allocated. However, more research is needed to examine barriers to HCV treatment in rural, underserved populations and in Federally Qualified Health Centers (FQHCs). As part of a quality improvement (QI) project, this study aimed to describe and evaluate the HCV treatment cascade in an FQHC serving a large rural patient population in the Western United States. Standardized chart abstraction was utilized to aggregate data regarding patient demographics, the percentage of patients achieving each step in the treatment cascade, and relevant patient (i.e., viral load) and service variables (i.e., whether and when patients received treatment or medication). 389 patients were identified as having HCV and 86% were aware of their diagnosis. Fifty-five percent had their infection confirmed via viral load, 21% were staged for liver disease, 24% received a prescription for treatment, and 19% achieved cure. Compared to national data, the current regional sample had greater rates of diagnosis awareness and access to care, as well as sustained virologic response (SVR), but lower rates of viral load confirmation. Current findings suggest that rural patients living with HCV who receive care at FQHCs struggle to navigate the treatment cascade and achieve a cure, particularly with regard to infection confirmation, liver staging, and prescription. However, compared to national estimates, patients had greater rates of diagnosis awareness/treatment access and SVR.

Entities:  

Keywords:  Care cascade; Federally Qualified Health Center; Hepatitis C; Quality improvement; Rural health

Year:  2020        PMID: 31512110     DOI: 10.1007/s10900-019-00736-4

Source DB:  PubMed          Journal:  J Community Health        ISSN: 0094-5145


  20 in total

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Authors:  Susan L Zickmund; Kyle E Brown; Klaus Bielefeldt
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2.  Knowledge about infection is the only predictor of treatment in patients with chronic hepatitis C.

Authors:  Z M Younossi; M Stepanova; M Afendy; B P Lam; A Mishra
Journal:  J Viral Hepat       Date:  2013-03-25       Impact factor: 3.728

3.  Expansion of Treatment for Hepatitis C Virus Infection by Task Shifting to Community-Based Nonspecialist Providers: A Nonrandomized Clinical Trial.

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Journal:  Ann Intern Med       Date:  2017-08-08       Impact factor: 25.391

4.  Baseline characteristics and mortality among people in care for chronic viral hepatitis: the chronic hepatitis cohort study.

Authors:  Anne C Moorman; Stuart C Gordon; Loralee B Rupp; Philip R Spradling; Eyasu H Teshale; Mei Lu; David R Nerenz; Cynthia C Nakasato; Joseph A Boscarino; Emily M Henkle; Nancy J Oja-Tebbe; Jian Xing; John W Ward; Scott D Holmberg
Journal:  Clin Infect Dis       Date:  2012-09-18       Impact factor: 9.079

5.  Identification and Clinical Management of Persons with Chronic Hepatitis C Virus Infection - Cherokee Nation, 2012-2015.

Authors:  Jorge Mera; Claudia Vellozzi; Susan Hariri; Hélène Carabin; Douglas A Drevets; Anna Miller; Brigg Reilley; Whitney Essex; David Gahn; Lisa Lyons; Jessica Leston; John W Ward
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2016-05-13       Impact factor: 17.586

6.  National patterns and predictors of liver biopsy use for management of hepatitis C.

Authors:  Erik J Groessl; Lin Liu; Samuel B Ho; Fasiha Kanwal; Allen L Gifford; Steven M Asch
Journal:  J Hepatol       Date:  2012-04-17       Impact factor: 25.083

7.  Process of care for hepatitis C infection is linked to treatment outcome and virologic response.

Authors:  Fasiha Kanwal; Tuyen Hoang; Timothy Chrusciel; Jennifer R Kramer; Hashem B El-Serag; Jason A Dominitz; Steven M Asch
Journal:  Clin Gastroenterol Hepatol       Date:  2012-07-25       Impact factor: 11.382

8.  Formal hepatitis C education enhances HCV care coordination, expedites HCV treatment and improves antiviral response.

Authors:  Samali Lubega; Uchenna Agbim; Miranda Surjadi; Megan Mahoney; Mandana Khalili
Journal:  Liver Int       Date:  2013-03-20       Impact factor: 5.828

9.  Primary Care Providers Knowledge, Attitude and Practices Related to Hepatitis C Screening and Treatment in the Oral Direct Acting Antiviral Agents Era.

Authors:  O Falade-Nwulia; A McAdams-Mahmoud; R Irvin; A Niculescu; K R Page; M Mix; D L Thomas; M S Sulkowski; S H Mehta
Journal:  J Community Med Health Educ       Date:  2016-10-28

10.  The Cascade of Care for an Australian Community-Based Hepatitis C Treatment Service.

Authors:  Amanda J Wade; Diana M Macdonald; Joseph S Doyle; Adam Gordon; Stuart K Roberts; Alexander J Thompson; Margaret E Hellard
Journal:  PLoS One       Date:  2015-11-12       Impact factor: 3.240

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  2 in total

1.  High prevalence of unawareness of HCV infection status among both HCV-seronegative and seropositive people living with human immunodeficiency virus in Taiwan.

Authors:  Chun-Yuan Lee; Pei-Hua Wu; Meng-Wei Lu; Tun-Chieh Chen; Po-Liang Lu
Journal:  PLoS One       Date:  2021-05-06       Impact factor: 3.240

2.  Development of an Interdisciplinary Telehealth Model of Provider Training and Comprehensive Care for Hepatitis C and Opioid Use Disorder in a High-Burden Region.

Authors:  Jacqueline E Sherbuk; Terry Kemp Knick; Chelsea Canan; Patrice Ross; Bailey Helbert; Eleanor Sue Cantrell; Charlene Joie Cantrell; Rachel Stallings; Nicole Barron; Diana Jordan; Kathleen A McManus; Rebecca Dillingham
Journal:  J Infect Dis       Date:  2020-09-02       Impact factor: 5.226

  2 in total

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