Mónica S Sierra1, Isabelle Soerjomataram2, Sébastien Antoni2, Mathieu Laversanne2, Marion Piñeros2, Esther de Vries3, David Forman2. 1. International Agency for Research on Cancer, Section of Cancer Surveillance, France. Electronic address: monica.sierra@alumni.uth.edu. 2. International Agency for Research on Cancer, Section of Cancer Surveillance, France. 3. Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogota, Colombia.
Abstract
RATIONALE AND OBJECTIVE: Cancer burden is increasing in Central and South America (CSA). We describe the current burden of cancer in CSA. METHODS: We obtained regional and national-level cancer incidence data from 48 population-based registries (13 countries) and nation-wide cancer mortality data from the WHO (18 countries). We estimated world population age-standardized incidence and mortality rates per 100,000 person-years. RESULTS: The leading cancers diagnosed were prostate, lung, breast, cervix, colorectal, and stomach, which were also the primary causes of cancer mortality. Countries of high/very high human development index (HDI) in the region experienced a high burden of prostate and breast cancer while medium HDI countries had a high burden of stomach and cervical cancers. Between countries, incidence and mortality from all cancers combined varied by 2-3-fold. French Guyana, Brazil, Uruguay, and Argentina had the highest incidence of all cancers while Uruguay, Cuba, Argentina, and Chile had the highest mortality. Incidence of colorectum, prostate and thyroid cancers increased in Argentina, Brazil, Chile and Costa Rica from 1997 to 2008, while lung, stomach and cervical cancers decreased. CONCLUSION: CSA carries a double-burden of cancer, with elevated rates of infection- and lifestyle-related cancers. Encountered variation in cancer rates between countries may reflect differences in registration practices, healthcare access, and public awareness. Resource-dependent interventions to prevent, early diagnose, and treat cancer remain an urgent priority. There is an overwhelming need to improve the quality and coverage of cancer registration to guide and evaluate future cancer control policies and programs.
RATIONALE AND OBJECTIVE:Cancer burden is increasing in Central and South America (CSA). We describe the current burden of cancer in CSA. METHODS: We obtained regional and national-level cancer incidence data from 48 population-based registries (13 countries) and nation-wide cancer mortality data from the WHO (18 countries). We estimated world population age-standardized incidence and mortality rates per 100,000 person-years. RESULTS: The leading cancers diagnosed were prostate, lung, breast, cervix, colorectal, and stomach, which were also the primary causes of cancer mortality. Countries of high/very high human development index (HDI) in the region experienced a high burden of prostate and breast cancer while medium HDI countries had a high burden of stomach and cervical cancers. Between countries, incidence and mortality from all cancers combined varied by 2-3-fold. French Guyana, Brazil, Uruguay, and Argentina had the highest incidence of all cancers while Uruguay, Cuba, Argentina, and Chile had the highest mortality. Incidence of colorectum, prostate and thyroid cancers increased in Argentina, Brazil, Chile and Costa Rica from 1997 to 2008, while lung, stomach and cervical cancers decreased. CONCLUSION:CSA carries a double-burden of cancer, with elevated rates of infection- and lifestyle-related cancers. Encountered variation in cancer rates between countries may reflect differences in registration practices, healthcare access, and public awareness. Resource-dependent interventions to prevent, early diagnose, and treat cancer remain an urgent priority. There is an overwhelming need to improve the quality and coverage of cancer registration to guide and evaluate future cancer control policies and programs.
Authors: Andrés López-Cortés; Santiago Guerrero; María Ana Redal; Angel Tito Alvarado; Luis Abel Quiñones Journal: Int J Mol Sci Date: 2017-05-23 Impact factor: 5.923
Authors: Gerardo Chacón; Johel E Rodríguez; Valmore Bermúdez; Miguel Vera; Juan Diego Hernández; Sandra Vargas; Aldo Pardo; Carlos Lameda; Delia Madriz; Antonio J Bravo Journal: F1000Res Date: 2018-07-17
Authors: Silvina Frech; Catherine A Muha; Lisa M Stevens; Edward L Trimble; Roxanne Brew; Doug Puricelli Perin; Silvana Luciani; Alejandro Mohar; Marion Piñeros; Tatiana Vidaurre; Douglas R Morgan; Ernest T Hawk; Kathleen M Schmeler; Lewis E Foxhall; Cristina Rabadan-Diehl; Denise Duran; Melissa Rendler-Garcia; Eduardo L Cazap; Luiz Santini; Walter Zoss; Lucia B Delgado; Paul C Pearlman; Leslie Given; Karin Hohman; Melissa S Lopez; Brenda Kostelecky Journal: J Glob Oncol Date: 2018-09