Literature DB >> 27601956

Reducing the dosimetric impact of positional errors in field junctions for craniospinal irradiation using VMAT.

Andrej Strojnik1, Ignasi Méndez1, Primož Peterlin1.   

Abstract

AIM: To improve treatment plan robustness with respect to small shifts in patient position during the VMAT treatment by ensuring a linear ramp-like dose profile in treatment field overlap regions.
BACKGROUND: Craniospinal irradiation (CSI) is considered technically challenging because the target size exceeds the maximal field size, which necessitates using abutted or overlapping treatment fields. Volumetric modulated arc therapy (VMAT) is increasingly being examined for CSI, as it offers both better dose homogeneity and better dose conformance while also offering a possibility to create field junctions which are more robust towards small shifts in patient position during the treatment.
MATERIALS AND METHODS: A VMAT treatment plan with three isocenters was made for a test case patient. Three groups of overlapping arc field pairs were used; one for the cranial and two for the spinal part. In order to assure a ramp-like dose profile in the field overlap region, the upper spinal part was optimised first, with dose prescription explicitly enforcing a ramp-like dose profile. The cranial and lower spinal part were done afterwards, taking into account the dose contribution of the upper spinal fields.
RESULTS: Using simple geometrical reasoning, we demonstrated that hot- and cold spots which arise from small displacement of one treatment field relative to the other treatment field can be reduced by taking two precautions: (a) widening the field overlap region, and (b) reducing the field gradient across the overlap region. The function with the smallest maximal gradient is a linear ramp. We present a treatment planning technique which yields the desired dose profile of the two contributing fields, and minimises dosimetric dependence on minor positional errors in patient set-up.

Entities:  

Keywords:  Craniospinal irradiation; Set-up error; Treatment field junction; VMAT

Year:  2016        PMID: 27601956      PMCID: PMC5002014          DOI: 10.1016/j.rpor.2016.03.002

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


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7.  Intensity-modulated radiation therapy and volumetric-modulated arc therapy for adult craniospinal irradiation--a comparison with traditional techniques.

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4.  Modified volumetric modulated arc therapy technique with reduced planning and treatment time for craniospinal irradiation utilising two isocentres.

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5.  A new strategy for craniospinal axis localization and adaptive dosimetric evaluation using cone beam CT.

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6.  Impact of setup errors on multi-isocenter volumetric modulated arc therapy for craniospinal irradiation.

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