Literature DB >> 27599510

Neuropeptide cycloprolylglycine increases the levels of brain-derived neurotrophic factor in neuronal cells.

T A Gudasheva1, K N Koliasnikova2, T A Antipova2, S B Seredenin2.   

Abstract

It was shown for the first time that the endogenous cyclic dipeptide cycloprolylglycine (CPG) at concentrations of 10(-7) and 10(-3) M and piracetam at a concentration of 10(-3) M increased the content of brainderived neurotrophic factor (BDNF) in the culture of neuronal cells in normal state and under conditions of glutamate and 6-oxydopamine neurotoxicity. This may indicate the possible involvement of BDNF in the mechanism of action of neuropeptide CPG and piracetam.

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Year:  2016        PMID： 27599510     DOI： 10.1134/S1607672916040104

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  8 in total

1.  [Novel endogenous dipeptide cycloprolyl-glycine is similar to pyracetam in selectivity of their mnemotropic effect].

Authors:  T A Gudasheva; R U Ostrovskaia; S S Trofimov; T A Voronina; A P Skoldinov; S B Seredenin
Journal:  Biull Eksp Biol Med       Date:  1999-10

Review 2.  Brain-derived neurotrophic factor and neuropsychiatric disorders.

Authors:  Anita E Autry; Lisa M Monteggia
Journal:  Pharmacol Rev       Date:  2012-03-08       Impact factor: 25.468

3.  [Similarity of cycloprolylglycine to piracetam in antihypoxic and neuroprotective effects].

Authors:  K N Kolisnikova; T A Gudasheva; G A Nazarova; T A Antipov; T A Voronina; S B Seredenin
Journal:  Eksp Klin Farmakol       Date:  2012

4.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

5.  Identification of a novel endogenous memory facilitating cyclic dipeptide cyclo-prolylglycine in rat brain.

Authors:  T A Gudasheva; S S Boyko; V Kh Akparov; R U Ostrovskaya; S P Skoldinov; G G Rozantsev; T A Voronina; V P Zherdev; S B Seredenin
Journal:  FEBS Lett       Date:  1996-08-05       Impact factor: 4.124

6.  Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.

Authors:  Ahmed H Ahmed; Robert E Oswald
Journal:  J Med Chem       Date:  2010-03-11       Impact factor: 7.446

7.  Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats.

Authors:  J Guan; S Mathai; P Harris; J-Y Wen; R Zhang; M Brimble; P Gluckman
Journal:  Neuropharmacology       Date:  2007-08-19       Impact factor: 5.250

8.  Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation.

Authors:  Hussam Jourdi; Yu-Tien Hsu; Miou Zhou; Qingyu Qin; Xiaoning Bi; Michel Baudry
Journal:  J Neurosci       Date:  2009-07-08       Impact factor: 6.167
  8 in total
  2 in total

1.  A New Component in the Mechanism of Regulation of Endogenous Depressive-Like States.

Authors:  T L Garibova; T A Gudasheva; S B Seredenin
Journal:  Dokl Biochem Biophys       Date:  2019-11-25       Impact factor: 0.788

2.  Neuropeptide cycloprolylglycine is an endogenous positive modulator of AMPA receptors.

Authors:  T A Gudasheva; V V Grigoriev; K N Koliasnikova; V L Zamoyski; S B Seredenin
Journal:  Dokl Biochem Biophys       Date:  2017-01-06       Impact factor: 0.788
  2 in total

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