Literature DB >> 27578894

The Heater Cooler as a Source of Infection from Nontuberculous Mycobacteria.

Alfred H Stammers1, Jeffrey B Riley2.   

Abstract

Nosocomial infections acquired during the course of cardiac surgery and hospitalization can have devastating patient consequences. The source of these infections is often difficult to determine which complicates eradication efforts. Recently it has become apparent that the heater-cooler devices used in conjunction with cardiopulmonary bypass may become contaminated with bacteria that are normally found in hospital water sources. The culprit organisms are nontuberculous mycobacteria which coat the intrinsic surfaces found within the circuits of the heater-coolers. Aerosolization of the bacteria occurs during normal heater-cooler operation which can disperse the organisms throughout the operating room. The bacteria are slow-growing and may not present for months, or years, following exposure which makes epidemiological determination a challenge. The ensuing report summarizes a recent outbreak in these infections that have been reported both in Europe and the United States, along with efforts to reduce the risk for patient infection.

Entities:  

Keywords:  cardiac surgery; cardiopulmonary bypass; heater–cooler device

Mesh:

Year:  2016        PMID: 27578894      PMCID: PMC5001521     

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  8 in total

1.  Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.

Authors:  Sebastian Haller; Christiane Höller; Anja Jacobshagen; Osamah Hamouda; Muna Abu Sin; Dominique L Monnet; Diamantis Plachouras; Tim Eckmanns
Journal:  Euro Surveill       Date:  2016-04-28

2.  Heater-cooler units: contamination of crucial devices in cardiothoracic surgery.

Authors:  T Götting; S Klassen; D Jonas; Ch Benk; A Serr; D Wagner; W Ebner
Journal:  J Hosp Infect       Date:  2016-02-27       Impact factor: 3.926

3.  Healthcare-associated prosthetic heart valve, aortic vascular graft, and disseminated Mycobacterium chimaera infections subsequent to open heart surgery.

Authors:  Philipp Kohler; Stefan P Kuster; Guido Bloemberg; Bettina Schulthess; Michelle Frank; Felix C Tanner; Matthias Rössle; Christian Böni; Volkmar Falk; Markus J Wilhelm; Rami Sommerstein; Yvonne Achermann; Jaap Ten Oever; Sylvia B Debast; Maurice J H M Wolfhagen; George J Brandon Bravo Bruinsma; Margreet C Vos; Ad Bogers; Annerose Serr; Friedhelm Beyersdorf; Hugo Sax; Erik C Böttger; Rainer Weber; Jakko van Ingen; Dirk Wagner; Barbara Hasse
Journal:  Eur Heart J       Date:  2015-07-17       Impact factor: 29.983

4.  Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery.

Authors:  Hugo Sax; Guido Bloemberg; Barbara Hasse; Rami Sommerstein; Philipp Kohler; Yvonne Achermann; Matthias Rössle; Volkmar Falk; Stefan P Kuster; Erik C Böttger; Rainer Weber
Journal:  Clin Infect Dis       Date:  2015-03-11       Impact factor: 9.079

5.  The heater-cooler unit--a conceivable source of infection.

Authors:  H H Weitkemper; A Spilker; H J Knobl; R Körfer
Journal:  J Extra Corpor Technol       Date:  2002-12

6.  Prosthetic valve endocarditis and bloodstream infection due to Mycobacterium chimaera.

Authors:  Yvonne Achermann; Matthias Rössle; Matthias Hoffmann; Vanessa Deggim; Stefan Kuster; Dieter R Zimmermann; Guido Bloemberg; Michael Hombach; Barbara Hasse
Journal:  J Clin Microbiol       Date:  2013-03-27       Impact factor: 5.948

7.  Decontamination of heater-cooler units associated with contamination by atypical mycobacteria.

Authors:  M I Garvey; R Ashford; C W Bradley; C R Bradley; T A Martin; J Walker; P Jumaa
Journal:  J Hosp Infect       Date:  2016-03-28       Impact factor: 3.926

8.  Transmission of Mycobacterium chimaera from Heater-Cooler Units during Cardiac Surgery despite an Ultraclean Air Ventilation System.

Authors:  Rami Sommerstein; Christian Rüegg; Philipp Kohler; Guido Bloemberg; Stefan P Kuster; Hugo Sax
Journal:  Emerg Infect Dis       Date:  2016-06-15       Impact factor: 6.883

  8 in total
  3 in total

1.  A Look Ahead (from Behind).

Authors:  Julie Wegner
Journal:  J Extra Corpor Technol       Date:  2016-06

2.  A New Culture Method for the Detection of Non-Tuberculous Mycobacteria in Water Samples from Heater-Cooler Units and Extracorporeal Membrane Oxygenation Machines.

Authors:  Savina Ditommaso; Monica Giacomuzzi; Gabriele Memoli; Jacopo Garlasco; Antonio Curtoni; Marco Iannaccone; Carla M Zotti
Journal:  Int J Environ Res Public Health       Date:  2022-08-26       Impact factor: 4.614

3.  Infections and outbreaks of nontuberculous mycobacteria in hospital settings.

Authors:  Angel N Desai; Rocío M Hurtado
Journal:  Curr Treat Options Infect Dis       Date:  2018-04-25
  3 in total

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