Literature DB >> 12533065

The heater-cooler unit--a conceivable source of infection.

H H Weitkemper1, A Spilker, H J Knobl, R Körfer.   

Abstract

Even drinking water is contaminated with pathogenic microorganisms. This does not necessarily pose a risk for healthy individuals, but it may result in serious consequences in people with impaired immune systems. This is particularly valid if drinking water is used for medical purposes. The heater-cooler unit (HCU) connected to heat exchangers or blankets by tubing, the connection is closed water circuit that contains microorganisms and algae. While connecting the tubing to the heat exchanger, spilling of water cannot be avoided. Microbiological examinations showed that germs and particles pollute the units. Exposure to the patient and the OR equipment has the potential to increase the risk of infection should the HCU water come in contact with the patient. As a result of the high incidence of particle and algae in the HCU, malfunction occurs. Sampling shows >1000/mL CFU (colony forming units) at 36 degrees C and 55/mL CFU at 20 degrees C on average. The specific findings include Pseudomonas and Legionella. Disinfecting HCU is very difficult. Often HCUs do not provide any technology to reduce bacterial or other contamination. The instructions for use of oxygenators often exclude the use of disinfectants. Maintenance instructions for the HCU advocate the use of disinfectants that carry the risk of oxygenator damage and of heat exchanger leakage. The effect of chemical disinfectants and heat exchanger membranes have not been examined, they may impair heat exchanger permeability and function. As an alternative to chemical and thermal disinfection, we used the alternative method of filtration. Using a membrane filter element, we noticed a decreasing number of CFUs from 55 to sterile conditions at 20 degrees C and from >1000 CFUs to 100 CFUs at 36 degrees C (Figure 1). In addition, we noticed a removal of other particles and algae. In conclusion, we have demonstrated a technique that is simple to implement and effectively reduces the microbiological load of the water in the heater-cooler unit.

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Mesh:

Year:  2002        PMID: 12533065

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  5 in total

1.  Classic Pages of the Journal of Extracorporeal Technology: Heater-Cooler Devices as a Conceivable Source of Infection.

Authors:  Jeffrey B Riley
Journal:  J Extra Corpor Technol       Date:  2016-06

2.  A Look Ahead (from Behind).

Authors:  Julie Wegner
Journal:  J Extra Corpor Technol       Date:  2016-06

3.  The Heater Cooler as a Source of Infection from Nontuberculous Mycobacteria.

Authors:  Alfred H Stammers; Jeffrey B Riley
Journal:  J Extra Corpor Technol       Date:  2016-06

4.  Target-Specific Assay for Rapid and Quantitative Detection of Mycobacterium chimaera DNA.

Authors:  Enrique Zozaya-Valdés; Jessica L Porter; John Coventry; Janet A M Fyfe; Glen P Carter; Anders Gonçalves da Silva; Mark B Schultz; Torsten Seemann; Paul D R Johnson; Andrew J Stewardson; Ivan Bastian; Sally A Roberts; Benjamin P Howden; Deborah A Williamson; Timothy P Stinear
Journal:  J Clin Microbiol       Date:  2017-04-05       Impact factor: 5.948

5.  Transmission of Mycobacterium chimaera from Heater-Cooler Units during Cardiac Surgery despite an Ultraclean Air Ventilation System.

Authors:  Rami Sommerstein; Christian Rüegg; Philipp Kohler; Guido Bloemberg; Stefan P Kuster; Hugo Sax
Journal:  Emerg Infect Dis       Date:  2016-06-15       Impact factor: 6.883

  5 in total

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