Literature DB >> 27570691

Comparison of tissue oximeters on a liquid phantom with adjustable optical properties.

S Kleiser1, N Nasseri2, B Andresen3, G Greisen3, M Wolf4.   

Abstract

The SafeBoosC trial showed that cerebral oximetry combined with a treatment guideline can reduce the the burden of hypoxia in neonates by 50% [Brit. Med. J.350, g7635 (2015)]. However, guidelines based on oximetry by one oximeter are not directly usable by other oximeters. We made a blood-lipid phantom simulating the neonatal head to determine the relation between oxygenation values obtained by different oximeters. We calculated coefficients for easy conversion from one oximeter to the other. We additionally determined the corresponding SafeBoosC intervention thresholds at which we measured an uncertainty of up to 9.2% when varying hemoglobin content from 25μM to 70μM. In conclusion, this paper makes the comparison of absolute values obtained by different oximeters possible.

Entities:  

Keywords:  (120.3890) Medical optics instrumentation; (170.6510) Spectroscopy, tissue diagnostics

Year:  2016        PMID： 27570691      PMCID： PMC4986807          DOI： 10.1364/BOE.7.002973

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


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