Literature DB >> 27402863

Chromatin and Epigenetics at the Forefront: Finding Clues among Peaks.

Sergi Aranda1, Yang Shi2, Luciano Di Croce3.   

Abstract

The Keystone Symposium on Chromatin and Epigenetics, organized by Luciano Di Croce (Center for Genomic Regulation, Spain) and Yang Shi (Harvard Medical School, USA), took place 20 to 24 March 2016 at Whistler (British Columbia, Canada). The symposium brought together some of the most outstanding scientists studying how chromatin structure and epigenetic mechanisms regulate gene function in both development and disease. Junior scientists had the opportunity to interact with experienced researchers by presenting their work and discussing ideas and novel hypotheses. In order to foster interaction and networking, the scientific agenda was balanced with an extended social agenda. This meeting review describes several of the most provocative and exciting talks from the symposium, revealing how fast this research field is evolving and the profound impact it will have on human health.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID: 27402863      PMCID: PMC5021377          DOI: 10.1128/MCB.00328-16

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  48 in total

1.  Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex.

Authors:  Hongjie Shen; Wenqi Xu; Rui Guo; Bowen Rong; Lei Gu; Zhentian Wang; Chenxi He; Lijuan Zheng; Xin Hu; Zhen Hu; Zhi-Ming Shao; Pengyuan Yang; Feizhen Wu; Yujiang Geno Shi; Yang Shi; Fei Lan
Journal:  Cell       Date:  2016-04-07       Impact factor: 41.582

2.  DNA Demethylation Dynamics in the Human Prenatal Germline.

Authors:  Sofia Gkountela; Kelvin X Zhang; Tiasha A Shafiq; Wen-Wei Liao; Joseph Hargan-Calvopiña; Pao-Yang Chen; Amander T Clark
Journal:  Cell       Date:  2015-05-21       Impact factor: 41.582

3.  Chromatin organization is a major influence on regional mutation rates in human cancer cells.

Authors:  Benjamin Schuster-Böckler; Ben Lehner
Journal:  Nature       Date:  2012-08-23       Impact factor: 49.962

4.  3D Chromosome Regulatory Landscape of Human Pluripotent Cells.

Authors:  Xiong Ji; Daniel B Dadon; Benjamin E Powell; Zi Peng Fan; Diego Borges-Rivera; Sigal Shachar; Abraham S Weintraub; Denes Hnisz; Gianluca Pegoraro; Tong Ihn Lee; Tom Misteli; Rudolf Jaenisch; Richard A Young
Journal:  Cell Stem Cell       Date:  2015-12-10       Impact factor: 24.633

5.  Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development.

Authors:  Stefan Bonn; Robert P Zinzen; Charles Girardot; E Hilary Gustafson; Alexis Perez-Gonzalez; Nicolas Delhomme; Yad Ghavi-Helm; Bartek Wilczyński; Andrew Riddell; Eileen E M Furlong
Journal:  Nat Genet       Date:  2012-01-08       Impact factor: 38.330

6.  Activation of proto-oncogenes by disruption of chromosome neighborhoods.

Authors:  Denes Hnisz; Abraham S Weintraub; Daniel S Day; Anne-Laure Valton; Rasmus O Bak; Charles H Li; Johanna Goldmann; Bryan R Lajoie; Zi Peng Fan; Alla A Sigova; Jessica Reddy; Diego Borges-Rivera; Tong Ihn Lee; Rudolf Jaenisch; Matthew H Porteus; Job Dekker; Richard A Young
Journal:  Science       Date:  2016-03-03       Impact factor: 47.728

7.  Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.

Authors:  Sam Behjati; Patrick S Tarpey; Nadège Presneau; Susanne Scheipl; Nischalan Pillay; Peter Van Loo; David C Wedge; Susanna L Cooke; Gunes Gundem; Helen Davies; Serena Nik-Zainal; Sancha Martin; Stuart McLaren; Victoria Goodie; Ben Robinson; Adam Butler; Jon W Teague; Dina Halai; Bhavisha Khatri; Ola Myklebost; Daniel Baumhoer; Gernot Jundt; Rifat Hamoudi; Roberto Tirabosco; M Fernanda Amary; P Andrew Futreal; Michael R Stratton; Peter J Campbell; Adrienne M Flanagan
Journal:  Nat Genet       Date:  2013-10-27       Impact factor: 38.330

8.  RNA biochemistry. Transcriptome-wide distribution and function of RNA hydroxymethylcytosine.

Authors:  Benjamin Delatte; Fei Wang; Long Vo Ngoc; Evelyne Collignon; Elise Bonvin; Rachel Deplus; Emilie Calonne; Bouchra Hassabi; Pascale Putmans; Stephan Awe; Collin Wetzel; Judith Kreher; Romuald Soin; Catherine Creppe; Patrick A Limbach; Cyril Gueydan; Véronique Kruys; Alexander Brehm; Svetlana Minakhina; Matthieu Defrance; Ruth Steward; François Fuks
Journal:  Science       Date:  2016-01-15       Impact factor: 47.728

9.  Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

Authors:  Lluis Morey; Gloria Pascual; Luca Cozzuto; Guglielmo Roma; Anton Wutz; Salvador Aznar Benitah; Luciano Di Croce
Journal:  Cell Stem Cell       Date:  2012-01-06       Impact factor: 24.633

10.  Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases.

Authors:  Yannick Jacob; Hume Stroud; Chantal Leblanc; Suhua Feng; Luting Zhuo; Elena Caro; Christiane Hassel; Crisanto Gutierrez; Scott D Michaels; Steven E Jacobsen
Journal:  Nature       Date:  2010-07-14       Impact factor: 49.962

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  2 in total

1.  SpikChIP: a novel computational methodology to compare multiple ChIP-seq using spike-in chromatin.

Authors:  Enrique Blanco; Luciano Di Croce; Sergi Aranda
Journal:  NAR Genom Bioinform       Date:  2021-07-27

2.  Pore-Forming Proteins as Mediators of Novel Epigenetic Mechanism of Epilepsy.

Authors:  Andrei Surguchov; Irina Surgucheva; Mukut Sharma; Ram Sharma; Vikas Singh
Journal:  Front Neurol       Date:  2017-01-18       Impact factor: 4.003

  2 in total

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