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Literature DB >> 27344519

Transcriptional regulation with CRISPR-Cas9: principles, advances, and applications.

Andriy Didovyk¹, Bartłomiej Borek¹, Lev Tsimring², Jeff Hasty³.

Abstract

CRISPR-Cas9 has recently emerged as a promising system for multiplexed genome editing as well as epigenome and transcriptome perturbation. Due to its specificity, ease of use and highly modular programmable nature, it has been widely adopted for a variety of applications such as genome editing, transcriptional inhibition and activation, genetic screening, DNA localization imaging, and many more. In this review, we will discuss non-editing applications of CRISPR-Cas9 for transcriptome perturbation, metabolic engineering, and synthetic biology.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2016 PMID： 27344519 PMCID： PMC4975649 DOI： 10.1016/j.copbio.2016.06.003

Source DB: PubMed Journal: Curr Opin Biotechnol ISSN： 0958-1669 Impact factor: 9.740

70 in total

1. CRISPR-Cas9 Based Engineering of Actinomycetal Genomes.

Authors: Yaojun Tong; Pep Charusanti; Lixin Zhang; Tilmann Weber; Sang Yup Lee
Journal: ACS Synth Biol Date: 2015-04-07 Impact factor: 5.110

2. Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9.

Authors: Andriy Didovyk; Bartłomiej Borek; Jeff Hasty; Lev Tsimring
Journal: ACS Synth Biol Date: 2015-09-30 Impact factor: 5.110

Review 3. High-throughput functional genomics using CRISPR-Cas9.

Authors: Ophir Shalem; Neville E Sanjana; Feng Zhang
Journal: Nat Rev Genet Date: 2015-04-09 Impact factor: 53.242

Review 4. Engineered gene circuits.

Authors: Jeff Hasty; David McMillen; J J Collins
Journal: Nature Date: 2002-11-14 Impact factor: 49.962

5. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.

Authors: Jason M Peters; Alexandre Colavin; Handuo Shi; Tomasz L Czarny; Matthew H Larson; Spencer Wong; John S Hawkins; Candy H S Lu; Byoung-Mo Koo; Elizabeth Marta; Anthony L Shiver; Evan H Whitehead; Jonathan S Weissman; Eric D Brown; Lei S Qi; Kerwyn Casey Huang; Carol A Gross
Journal: Cell Date: 2016-05-26 Impact factor: 41.582

6. Application of CRISPRi for prokaryotic metabolic engineering involving multiple genes, a case study: Controllable P(3HB-co-4HB) biosynthesis.

Authors: Li Lv; Yi-Lin Ren; Jin-Chun Chen; Qiong Wu; Guo-Qiang Chen
Journal: Metab Eng Date: 2015-03-31 Impact factor: 9.783

7. Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

Authors: Lior Nissim; Samuel D Perli; Alexandra Fridkin; Pablo Perez-Pinera; Timothy K Lu
Journal: Mol Cell Date: 2014-05-15 Impact factor: 17.970

8. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.

Authors: Prashant Mali; John Aach; P Benjamin Stranges; Kevin M Esvelt; Mark Moosburner; Sriram Kosuri; Luhan Yang; George M Church
Journal: Nat Biotechnol Date: 2013-08-01 Impact factor: 54.908

Review 9. Enhancing stress-resistance for efficient microbial biotransformations by synthetic biology.

Authors: Haiyang Jia; Yanshuang Fan; Xudong Feng; Chun Li
Journal: Front Bioeng Biotechnol Date: 2014-10-20

10. RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Authors: Pablo Perez-Pinera; D Dewran Kocak; Christopher M Vockley; Andrew F Adler; Ami M Kabadi; Lauren R Polstein; Pratiksha I Thakore; Katherine A Glass; David G Ousterout; Kam W Leong; Farshid Guilak; Gregory E Crawford; Timothy E Reddy; Charles A Gersbach
Journal: Nat Methods Date: 2013-07-25 Impact factor: 28.547

24 in total

1. Diversity of CRISPR/Cas system in Clostridium perfringens.

Authors: Jinzhao Long; Yake Xu; Liuyang Ou; Haiyan Yang; Yuanlin Xi; Shuaiyin Chen; Guangcai Duan
Journal: Mol Genet Genomics Date: 2019-05-27 Impact factor: 3.291

Review 2. Synthetic Biology: Engineering Living Systems from Biophysical Principles.

Authors: Bryan A Bartley; Kyung Kim; J Kyle Medley; Herbert M Sauro
Journal: Biophys J Date: 2017-03-28 Impact factor: 4.033

Review 3. Recent advances in CRISPR/Cas9 mediated genome editing in Bacillus subtilis.

Authors: Kun-Qiang Hong; Ding-Yu Liu; Tao Chen; Zhi-Wen Wang
Journal: World J Microbiol Biotechnol Date: 2018-09-29 Impact factor: 3.312

Review 4. Rational engineering of synthetic microbial systems: from single cells to consortia.

Authors: Philip Bittihn; M Omar Din; Lev S Tsimring; Jeff Hasty
Journal: Curr Opin Microbiol Date: 2018-03-22 Impact factor: 7.934

5. Massively parallel CRISPRi assays reveal concealed thermodynamic determinants of dCas12a binding.

Authors: David A Specht; Yasu Xu; Guillaume Lambert
Journal: Proc Natl Acad Sci U S A Date: 2020-05-06 Impact factor: 11.205

Review 6. Dead Cas(t) light on new life: CRISPRa-mediated reprogramming of somatic cells into neurons.

Authors: Meiling Zhou; Yu Cao; Ming Sui; Xiji Shu; Feng Wan; Bin Zhang
Journal: Cell Mol Life Sci Date: 2022-05-24 Impact factor: 9.261

7. Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis.

Authors: Yaokang Wu; Taichi Chen; Yanfeng Liu; Rongzhen Tian; Xueqin Lv; Jianghua Li; Guocheng Du; Jian Chen; Rodrigo Ledesma-Amaro; Long Liu
Journal: Nucleic Acids Res Date: 2020-01-24 Impact factor: 16.971