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Literature DB >> 27341693

Design and engineering of artificial oxygen-activating metalloenzymes.

Flavia Nastri¹, Marco Chino, Ornella Maglio, Ambika Bhagi-Damodaran, Yi Lu, Angela Lombardi.

Abstract

Many efforts are being made in the design and engineering of metalloenzymes with catalytic properties fulfilling the needs of practical applications. Progress in this field has recently been accelerated by advances in computational, molecular and structural biology. This review article focuses on the recent examples of oxygen-activating metalloenzymes, developed through the strategies of de novo design, miniaturization processes and protein redesign. Considerable progress in these diverse design approaches has produced many metal-containing biocatalysts able to adopt the functions of native enzymes or even novel functions beyond those found in Nature.

Entities: Chemical

Mesh：

Substances：

Year: 2016 PMID： 27341693 PMCID： PMC5021598 DOI： 10.1039/c5cs00923e

Source DB: PubMed Journal: Chem Soc Rev ISSN： 0306-0012 Impact factor: 54.564

262 in total

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Journal: Protein Sci Date: 2003-01 Impact factor: 6.725

2. Metalloproteins: Simple structure, complex function.

Authors: Angela Lombardi
Journal: Nat Chem Biol Date: 2015-10 Impact factor: 15.040

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Authors: Jun-Long Zhang; Dewain K Garner; Lei Liang; Qian Chen; Yi Lu
Journal: Chem Commun (Camb) Date: 2008-02-04 Impact factor: 6.222

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Authors: Caroline J Rodgers; Christopher F Blanford; Stephen R Giddens; Pari Skamnioti; Fraser A Armstrong; Sarah J Gurr
Journal: Trends Biotechnol Date: 2009-12-04 Impact factor: 19.536

5. Role of heme types in heme-copper oxidases: effects of replacing a heme b with a heme o mimic in an engineered heme-copper center in myoglobin.

Authors: Ningyan Wang; Xuan Zhao; Yi Lu
Journal: J Am Chem Soc Date: 2005-11-30 Impact factor: 15.419

6. Artificial di-iron proteins: solution characterization of four helix bundles containing two distinct types of inter-helical loops.

Authors: Ornella Maglio; Flavia Nastri; Jennifer R Calhoun; Stephen Lahr; Herschel Wade; Vincenzo Pavone; William F DeGrado; Angela Lombardi
Journal: J Biol Inorg Chem Date: 2005-09-23 Impact factor: 3.358

7. A de novo protein binding pair by computational design and directed evolution.

Authors: John Karanicolas; Jacob E Corn; Irwin Chen; Lukasz A Joachimiak; Orly Dym; Sun H Peck; Shira Albeck; Tamar Unger; Wenxin Hu; Gaohua Liu; Scott Delbecq; Gaetano T Montelione; Clint P Spiegel; David R Liu; David Baker
Journal: Mol Cell Date: 2011-03-31 Impact factor: 17.970

Review 8. Methane monooxygenase: functionalizing methane at iron and copper.

Authors: Matthew H Sazinsky; Stephen J Lippard
Journal: Met Ions Life Sci Date: 2015

9. Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2.

Authors: Megan L Matthews; Christopher S Neumann; Linde A Miles; Tyler L Grove; Squire J Booker; Carsten Krebs; Christopher T Walsh; J Martin Bollinger
Journal: Proc Natl Acad Sci U S A Date: 2009-10-06 Impact factor: 11.205

10. Toward the synthesis of more reactive S = 2 non-heme oxoiron(IV) complexes.

Authors: Mayank Puri; Lawrence Que
Journal: Acc Chem Res Date: 2015-07-15 Impact factor: 22.384

38 in total

1. Histidine-Lysine Axial Ligand Switching in a Hemoglobin: A Role for Heme Propionates.

Authors: Dillon B Nye; Matthew R Preimesberger; Ananya Majumdar; Juliette T J Lecomte
Journal: Biochemistry Date: 2018-01-10 Impact factor: 3.162

Review 2. Design of artificial metalloproteins/metalloenzymes by tuning noncovalent interactions.

Authors: Shun Hirota; Ying-Wu Lin
Journal: J Biol Inorg Chem Date: 2017-12-07 Impact factor: 3.358

Review 3. Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.

Authors: Xiongyi Huang; John T Groves
Journal: Chem Rev Date: 2017-12-29 Impact factor: 60.622

4. d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils.

Authors: Leela Ruckthong; Anna F A Peacock; Cherilyn E Pascoe; Lars Hemmingsen; Jeanne A Stuckey; Vincent L Pecoraro
Journal: Chemistry Date: 2017-05-26 Impact factor: 5.236

5. Critical Aspects of Heme-Peroxo-Cu Complex Structure and Nature of Proton Source Dictate Metal-O(peroxo) Breakage versus Reductive O-O Cleavage Chemistry.

Authors: Suzanne M Adam; Isaac Garcia-Bosch; Andrew W Schaefer; Savita K Sharma; Maxime A Siegler; Edward I Solomon; Kenneth D Karlin
Journal: J Am Chem Soc Date: 2016-12-28 Impact factor: 15.419

6. Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases.

Authors: Kelsey R Miller; Jonathan D Paretsky; Alec H Follmer; Tillmann Heinisch; Kaustuv Mittra; Sheraz Gul; In-Sik Kim; Franklin D Fuller; Alexander Batyuk; Kyle D Sutherlin; Aaron S Brewster; Asmit Bhowmick; Nicholas K Sauter; Jan Kern; Junko Yano; Michael T Green; Thomas R Ward; A S Borovik
Journal: Inorg Chem Date: 2020-04-20 Impact factor: 5.165

7. Hydrogen-Atom Transfer Oxidation with H₂O₂ Catalyzed by [FeII(1,2-bis(2,2'-bipyridyl-6-yl)ethane(H₂O)₂]²⁺: Likely Involvement of a (μ-Hydroxo)(μ-1,2-peroxo)diiron(III) Intermediate.

Authors: Alexander M Khenkin; Madhu Vedichi; Linda J W Shimon; Matthew A Cranswick; Johannes E M N Klein; Lawrence Que; Ronny Neumann
Journal: Isr J Chem Date: 2017-09-13 Impact factor: 3.333