Literature DB >> 27234562

The many faces of histone H3K79 methylation.

Zeenat Farooq1, Shahid Banday1, Tej K Pandita2, Mohammad Altaf3.   

Abstract

Dot1/DOT1L (disruptor of telomeric silencing-1) is an evolutionarily conserved histone methyltransferase that methylates lysine 79 located within the globular domain of histone H3. Dot1 was initially identified by a genetic screen as a disruptor of telomeric silencing in Saccharomyces cerevisiae; further, it is the only known non-SET domain containing histone methyltransferase. Methylation of H3K79 is involved in the regulation of telomeric silencing, cellular development, cell-cycle checkpoint, DNA repair, and regulation of transcription. hDot1L-mediated H3K79 methylation appears to have a crucial role in transformation as well as disease progression in leukemias involving several oncogenic fusion proteins. This review summarizes the multiple functions of Dot1/hDOT1L in a range of cellular processes.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Chromatin; DNA repair; Histone methylation

Mesh：

Substances：

Year:  2016        PMID： 27234562      PMCID： PMC4889126          DOI： 10.1016/j.mrrev.2016.03.005

Source DB:  PubMed          Journal:  Mutat Res Rev Mutat Res        ISSN： 1383-5742            Impact factor:   5.657


  86 in total

Review 1.  Connection between histone H2A variants and chromatin remodeling complexes.

Authors:  Mohammed Altaf; Andréanne Auger; Marcela Covic; Jacques Côté
Journal:  Biochem Cell Biol       Date:  2009-02       Impact factor: 3.626

2.  Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.

Authors:  Matthew G Guenther; Lee N Lawton; Tatiana Rozovskaia; Garrett M Frampton; Stuart S Levine; Thomas L Volkert; Carlo M Croce; Tatsuya Nakamura; Eli Canaani; Richard A Young
Journal:  Genes Dev       Date:  2008-12-15       Impact factor: 11.361

3.  Combinatorial patterns of histone acetylations and methylations in the human genome.

Authors:  Zhibin Wang; Chongzhi Zang; Jeffrey A Rosenfeld; Dustin E Schones; Artem Barski; Suresh Cuddapah; Kairong Cui; Tae-Young Roh; Weiqun Peng; Michael Q Zhang; Keji Zhao
Journal:  Nat Genet       Date:  2008-06-15       Impact factor: 38.330

4.  Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae: regulation of DNA damage tolerance by the error-prone polymerases Polzeta/Rev1.

Authors:  Francisco Conde; Pedro A San-Segundo
Journal:  Genetics       Date:  2008-06-18       Impact factor: 4.562

5.  Nonredundant requirement for multiple histone modifications for the early anaphase release of the mitotic exit regulator Cdc14 from nucleolar chromatin.

Authors:  William W Hwang; Hiten D Madhani
Journal:  PLoS Genet       Date:  2009-08-07       Impact factor: 5.917

6.  Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors.

Authors:  Craig D Jude; Leslie Climer; Diyong Xu; Erika Artinger; Jill K Fisher; Patricia Ernst
Journal:  Cell Stem Cell       Date:  2007-09-13       Impact factor: 24.633

7.  Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation.

Authors:  Julia M Schulze; Jessica Jackson; Shima Nakanishi; Jennifer M Gardner; Thomas Hentrich; Jeff Haug; Mark Johnston; Sue L Jaspersen; Michael S Kobor; Ali Shilatifard
Journal:  Mol Cell       Date:  2009-08-13       Impact factor: 17.970

8.  H3K79 methylation profiles define murine and human MLL-AF4 leukemias.

Authors:  Andrei V Krivtsov; Zhaohui Feng; Madeleine E Lemieux; Joerg Faber; Sridhar Vempati; Amit U Sinha; Xiaobo Xia; Jonathan Jesneck; Adrian P Bracken; Lewis B Silverman; Jeffery L Kutok; Andrew L Kung; Scott A Armstrong
Journal:  Cancer Cell       Date:  2008-11-04       Impact factor: 31.743

9.  Reconstitution of heterochromatin-dependent transcriptional gene silencing.

Authors:  Aaron Johnson; Geng Li; Timothy W Sikorski; Stephen Buratowski; Christopher L Woodcock; Danesh Moazed
Journal:  Mol Cell       Date:  2009-09-24       Impact factor: 17.970

10.  Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres.

Authors:  Federico Lazzaro; Vasileia Sapountzi; Magda Granata; Achille Pellicioli; Moreshwar Vaze; James E Haber; Paolo Plevani; David Lydall; Marco Muzi-Falconi
Journal:  EMBO J       Date:  2008-04-17       Impact factor: 11.598
View more
  47 in total

1.  Vigilin protein Vgl1 is required for heterochromatin-mediated gene silencing in Schizosaccharomyces pombe.

Authors:  Zeenat Farooq; Ehsaan Abdullah; Shahid Banday; Shabir Ahmad Ganai; Romana Rashid; Arjamand Mushtaq; Samia Rashid; Mohammad Altaf
Journal:  J Biol Chem       Date:  2019-09-25       Impact factor: 5.157

Review 2.  Preserving genome integrity and function: the DNA damage response and histone modifications.

Authors:  Jae Jin Kim; Seo Yun Lee; Kyle M Miller
Journal:  Crit Rev Biochem Mol Biol       Date:  2019-06-04       Impact factor: 8.250

Review 3.  Reprogramming: identifying the mechanisms that safeguard cell identity.

Authors:  Justin Brumbaugh; Bruno Di Stefano; Konrad Hochedlinger
Journal:  Development       Date:  2019-12-02       Impact factor: 6.868

4.  Functional genomic characterization of the FTO locus in African Americans.

Authors:  Richard Gill; George Stratigopoulos; Joseph H Lee; Rudolph L Leibel
Journal:  Physiol Genomics       Date:  2019-09-18       Impact factor: 3.107

Review 5.  Histone methylation and the DNA damage response.

Authors:  Fade Gong; Kyle M Miller
Journal:  Mutat Res Rev Mutat Res       Date:  2017-09-23       Impact factor: 5.657

Review 6.  Is There a Histone Code for Cellular Quiescence?

Authors:  Kenya Bonitto; Kirthana Sarathy; Kaiser Atai; Mithun Mitra; Hilary A Coller
Journal:  Front Cell Dev Biol       Date:  2021-10-29

Review 7.  Histone variant-specific post-translational modifications.

Authors:  Faith M Joseph; Nicolas L Young
Journal:  Semin Cell Dev Biol       Date:  2022-03-09       Impact factor: 7.499

8.  Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response.

Authors:  Laura Marcos-Villar; Juan Díaz-Colunga; Juan Sandoval; Noelia Zamarreño; Sara Landeras-Bueno; Manel Esteller; Ana Falcón; Amelia Nieto
Journal:  Sci Rep       Date:  2018-01-19       Impact factor: 4.379

9.  Identification of SET Domain-Containing Proteins in Gossypium raimondii and Their Response to High Temperature Stress.

Authors:  Yong Huang; Yijia Mo; Pengyun Chen; Xiaoling Yuan; Funing Meng; Shengwei Zhu; Zhi Liu
Journal:  Sci Rep       Date:  2016-09-07       Impact factor: 4.379

10.  Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice.

Authors:  Pearl A Sutter; Sangita Karki; Ilan Crawley; Vijender Singh; Kathrin M Bernt; David W Rowe; Stephen J Crocker; Dashzeveg Bayarsaihan; Rosa M Guzzo
Journal:  Bone       Date:  2020-10-03       Impact factor: 4.398
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.