| Literature DB >> 27108036 |
Kenneth B Bader1, Michael J Crowe2, Jason L Raymond2, Christy K Holland3.
Abstract
Tissue-mimicking phantoms are employed for the assessment of shocked histotripsy pulses in vitro. These broadband shock waves are critical for tissue ablation and are influenced by the frequency-dependent attenuation of the medium. The density, sound speed and attenuation spectra (2-25 MHz) were measured for phantoms that mimic key histotripsy targets. The influence of non-linear propagation relative to the attenuation was described in terms of Gol'dberg number. An expression was derived to estimate the bandwidth of shocked histotripsy pulses for power law-dependent attenuation. The expression is independent of the fundamental frequency of the histotripsy pulse for linear frequency-dependent attenuation.Entities:
Keywords: Acoustical properties; Cavitation; Histotripsy; Shock waves; Ultrasonic attenuation
Mesh:
Year: 2016 PMID: 27108036 PMCID: PMC4899262 DOI: 10.1016/j.ultrasmedbio.2016.02.010
Source DB: PubMed Journal: Ultrasound Med Biol ISSN: 0301-5629 Impact factor: 2.998