Literature DB >> 27095489

CncRNAs: RNAs with both coding and non-coding roles in development.

Karuna Sampath1, Anne Ephrussi2.   

Abstract

RNAs are known to regulate diverse biological processes, either as protein-encoding molecules or as non-coding RNAs. However, a third class that comprises RNAs endowed with both protein coding and non-coding functions has recently emerged. Such bi-functional 'coding and non-coding RNAs' (cncRNAs) have been shown to play important roles in distinct developmental processes in plants and animals. Here, we discuss key examples of cncRNAs and review their roles, regulation and mechanisms of action during development.
© 2016. Published by The Company of Biologists Ltd.

Keywords:  Bifunctional RNA; CncRNAs; Coding RNA; Development; Non-coding RNA; Regulatory RNA

Mesh:

Substances:

Year:  2016        PMID: 27095489     DOI: 10.1242/dev.133298

Source DB:  PubMed          Journal:  Development        ISSN: 0950-1991            Impact factor:   6.868


  17 in total

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Review 4.  'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

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Review 8.  Post-transcriptional Processing of mRNA in Neurons: The Vestiges of the RNA World Drive Transcriptome Diversity.

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9.  A Functional Non-coding RNA Is Produced from xbp-1 mRNA.

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10.  Sequences encoding C2H2 zinc fingers inhibit polyadenylation and mRNA export in human cells.

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