Literature DB >> 27087758

"Bureaucracy & Beliefs": Assessing the Barriers to Accessing Opioid Substitution Therapy by People Who Inject Drugs in Ukraine.

Martha J Bojko1, Alyona Mazhnaya2, Iuliia Makarenko3, Ruthanne Marcus1, Sergii Dvoriak3, Zahedul Islam2, Frederick L Altice4.   

Abstract

AIMS: Opioid substitution therapy (OST) is an evidence-based HIV prevention strategy for people who inject drugs (PWIDs). Yet, only 2.7% of Ukraine's estimated 310,000 PWIDs receive it despite free treatment since 2004. The multi-level barriers to entering OST among opioid dependent PWIDs have not been examined in Ukraine.
METHODS: A multi-year mixed methods implementation science project included focus group discussions with 199 PWIDs in 5 major Ukrainian cities in 2013 covering drug treatment attitudes and beliefs and knowledge of and experiences with OST. Data were transcribed, translated into English and coded. Coded segments related to OST access, entry, knowledge, beliefs and attitudes were analyzed among 41 PWIDs who were eligible for but had never received OST.
FINDINGS: A number of programmatic and structural barriers were mentioned by participants as barriers to entry to OST, including compulsory drug user registration, waiting lists, and limited number of treatment slots. Participants also voiced strong negative attitudes and beliefs about OST, especially methadone. Their perceptions about methadone's side effects as well as the stigma of being a methadone client were expressed as obstacles to treatment.
CONCLUSIONS: Despite expressed interest in treatment, Ukrainian OST-naïve PWIDs evade OST for reasons that can be addressed through changes in program-level and governmental policies and social-marketing campaigns. Voiced OST barriers can effectively inform public health and policy directives related to HIV prevention and treatment in Ukraine to improve evidence-based treatment access and availability.

Entities:  

Keywords:  Substance abuse; Ukraine; buprenorphine; health beliefs; methadone; opioid substitution therapy; people who inject drugs; qualitative research; treatment barriers

Year:  2015        PMID: 27087758      PMCID: PMC4831711          DOI: 10.3109/09687637.2015.1016397

Source DB:  PubMed          Journal:  Drugs (Abingdon Engl)        ISSN: 0968-7637


  44 in total

1.  Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users.

Authors:  Sasha Uhlmann; M-J Milloy; Thomas Kerr; Ruth Zhang; Silvia Guillemi; David Marsh; Robert S Hogg; Julio S G Montaner; Evan Wood
Journal:  Addiction       Date:  2010-03-10       Impact factor: 6.526

Review 2.  The effectiveness of social marketing interventions for health improvement: what's the evidence?

Authors:  Ross Gordon; Laura McDermott; Martine Stead; Kathryn Angus
Journal:  Public Health       Date:  2006-11-13       Impact factor: 2.427

3.  Effectiveness of strategies for informing, educating, and involving patients.

Authors:  Angela Coulter; Jo Ellins
Journal:  BMJ       Date:  2007-07-07

Review 4.  What has been achieved in HIV prevention, treatment and care for people who inject drugs, 2010-2012? A review of the six highest burden countries.

Authors:  Louisa Degenhardt; Bradley M Mathers; Andrea L Wirtz; Daniel Wolfe; Adeeba Kamarulzaman; M Patrizia Carrieri; Steffanie A Strathdee; Kasia Malinowska-Sempruch; Michel Kazatchkine; Chris Beyrer
Journal:  Int J Drug Policy       Date:  2013-09-04

5.  Patient preferences and randomised clinical trials.

Authors:  C R Brewin; C Bradley
Journal:  BMJ       Date:  1989-07-29

6.  Opiate users' perceived barriers against attending methadone maintenance therapy: a qualitative study in China.

Authors:  Chunqing Lin; Zunyou Wu; Roger Detels
Journal:  Subst Use Misuse       Date:  2011-03-21       Impact factor: 2.164

7.  Controlling HIV among people who inject drugs in Eastern Europe and Central Asia: insights from modeling.

Authors:  Peter Vickerman; Lucy Platt; Emma Jolley; Tim Rhodes; Michel D Kazatchkine; Alisher Latypov
Journal:  Int J Drug Policy       Date:  2014-11

8.  Are randomized controlled trials controlled? Patient preferences and unblind trials.

Authors:  K McPherson; A R Britton; J E Wennberg
Journal:  J R Soc Med       Date:  1997-12       Impact factor: 5.344

9.  Key findings from the WHO collaborative study on substitution therapy for opioid dependence and HIV/AIDS.

Authors:  Peter Lawrinson; Robert Ali; Aumphornpun Buavirat; Sithisat Chiamwongpaet; Sergey Dvoryak; Boguslaw Habrat; Shi Jie; Ratna Mardiati; Azarakhsh Mokri; Jacek Moskalewicz; David Newcombe; Vladimir Poznyak; Emilis Subata; Ambrose Uchtenhagen; Diah S Utami; Robyn Vial; Chengzheng Zhao
Journal:  Addiction       Date:  2008-07-10       Impact factor: 6.526

10.  Integration and co-location of HIV/AIDS, tuberculosis and drug treatment services.

Authors:  Laurie Sylla; R Douglas Bruce; Adeeba Kamarulzaman; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2007-05-10
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  34 in total

1.  Estimating HIV and HCV prevalence among people who inject drugs in 5 Ukrainian cities using stratification-based respondent driven and random sampling.

Authors:  Alexei Zelenev; Portia Shea; Alyona Mazhnaya; Anna Meteliuk; Iryna Pykalo; Ruthanne Marcus; Tatiana Fomenko; Tatiana Prokhorova; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2018-11-29

2.  Hepatitis C virus status awareness and test results confirmation among people who inject drugs in Ukraine.

Authors:  Olena Iakunchykova; Anna Meteliuk; Alexei Zelenev; Alyona Mazhnaya; Melissa Tracy; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2018-04-12

3.  Patient preferences and extended-release naltrexone: A new opportunity to treat opioid use disorders in Ukraine.

Authors:  Ruthanne Marcus; Iuliia Makarenko; Alyona Mazhnaya; Alexei Zelenev; Maxim Polonsky; Lynn Madden; Sergii Filippovych; Sergii Dvoriak; Sandra A Springer; Frederick L Altice
Journal:  Drug Alcohol Depend       Date:  2017-08-05       Impact factor: 4.492

4.  Retention in medication-assisted treatment programs in Ukraine-Identifying factors contributing to a continuing HIV epidemic.

Authors:  Kostyantyn Dumchev; Sergii Dvoryak; Olena Chernova; Olga Morozova; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2017-08-08

5.  Struggling to achieve a 'normal life': A qualitative study of Vietnamese methadone patients.

Authors:  Thu Trang Nguyen; Anh Ngoc Luong; Thi Tuyet Thanh Nham; Carole Chauvin; Jonathan Feelemyer; Nicolas Nagot; Don Des Jarlais; Minh Giang Le; Marie Jauffret-Roustide
Journal:  Int J Drug Policy       Date:  2019-04-09

6.  Willingness to pay for opioid agonist treatment among opioid dependent people who inject drugs in Ukraine.

Authors:  Iuliia Makarenko; Alyona Mazhnaya; Ruthanne Marcus; Martha J Bojko; Lynn Madden; Sergii Filippovich; Sergii Dvoriak; Frederick L Altice
Journal:  Int J Drug Policy       Date:  2017-06-16

7.  Opioid Agonist Treatment and Improved Outcomes at Each Stage of the HIV Treatment Cascade in People Who Inject Drugs in Ukraine.

Authors:  Alyona Mazhnaya; Ruthanne Marcus; Martha J Bojko; Alexei Zelenev; Iuliia Makarenko; Iryna Pykalo; Sergii Filippovych; Sergii Dvoriak; Frederick L Altice
Journal:  J Acquir Immune Defic Syndr       Date:  2018-11-01       Impact factor: 3.731

Review 8.  Integrated opioid substitution therapy and HIV care: a qualitative systematic review and synthesis of client and provider experiences.

Authors:  Andy Guise; Maureen Seguin; Gitau Mburu; Susie McLean; Pippa Grenfell; Zahed Islam; Sergii Filippovych; Happy Assan; Andrea Low; Peter Vickerman; Tim Rhodes
Journal:  AIDS Care       Date:  2017-03-10

9.  Treating opioid dependence with extended-release naltrexone (XR-NTX) in Ukraine: Feasibility and three-month outcomes.

Authors:  Iuliia Makarenko; Iryna Pykalo; Sandra A Springer; Alyona Mazhnaya; Ruthanne Marcus; Sergii Filippovich; Sergii Dvoriak; Frederick L Altice
Journal:  J Subst Abuse Treat       Date:  2019-05-10

10.  In Their Own Voices: Breaking the Vicious Cycle of Addiction, Treatment and Criminal Justice Among People who Inject Drugs in Ukraine.

Authors:  Alyona Mazhnaya; Martha J Bojko; Ruthanne Marcus; Sergii Filippovych; Zahedsul Islam; Sergey Dvoriak; Frederick L Altice
Journal:  Drugs (Abingdon Engl)       Date:  2016-02-16
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