George Patounakis1, Meghan C Ozcan2, Rebecca J Chason2, John M Norian3, Mark Payson4, Alan H DeCherney1, Belinda J Yauger5. 1. National Institutes of Health/National Institute of Child Health and Human Development, Bethesda, Maryland. 2. Walter Reed National Military Medical Center, Bethesda, Maryland. 3. HRC Fertility, Pasadena, California. 4. Dominion Fertility, Arlington, Virginia; Inova Fairfax Hospital Women's Center, Falls Church, Virginia. 5. Walter Reed National Military Medical Center, Bethesda, Maryland. Electronic address: belinda.j.yauger.mil@mail.mil.
Abstract
OBJECTIVE: To determine whether a history of prior cesarean delivery (CD) makes ET more difficult and impacts pregnancy outcomes. DESIGN: Prospective cohort study. SETTING: Tertiary care military facility. PATIENT(S): One hundred ninety-four patients with previous delivery undergoing IVF/intracytoplasmic sperm injection (ICSI)-ET. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Live birth (primary), positive hCG, clinical pregnancy, and time to perform ET. RESULT(S): There was no statistically significant difference between patients with a history of only vaginal deliveries versus those with a history of CD for live birth (39% vs. 32%), positive hCG (56% vs. 53%), or clinical pregnancy (49% vs. 41%). Embryo transfers took longer in the history of CD group (157 vs. 187 seconds) and were more likely to have mucus (27% vs. 45%) or blood (8% vs. 21%) on the catheter. CONCLUSION(S): Embryo transfers performed on patients with a prior CD took 30 seconds longer. They were also more likely to have blood or mucus on the catheter. Despite the apparently more difficult transfers, pregnancy outcomes were not different between the two groups. Published by Elsevier Inc.
OBJECTIVE: To determine whether a history of prior cesarean delivery (CD) makes ET more difficult and impacts pregnancy outcomes. DESIGN: Prospective cohort study. SETTING: Tertiary care military facility. PATIENT(S): One hundred ninety-four patients with previous delivery undergoing IVF/intracytoplasmic sperm injection (ICSI)-ET. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Live birth (primary), positive hCG, clinical pregnancy, and time to perform ET. RESULT(S): There was no statistically significant difference between patients with a history of only vaginal deliveries versus those with a history of CD for live birth (39% vs. 32%), positive hCG (56% vs. 53%), or clinical pregnancy (49% vs. 41%). Embryo transfers took longer in the history of CD group (157 vs. 187 seconds) and were more likely to have mucus (27% vs. 45%) or blood (8% vs. 21%) on the catheter. CONCLUSION(S): Embryo transfers performed on patients with a prior CD took 30 seconds longer. They were also more likely to have blood or mucus on the catheter. Despite the apparently more difficult transfers, pregnancy outcomes were not different between the two groups. Published by Elsevier Inc.
Authors: C Regnard; M Nosbusch; C Fellemans; N Benali; M van Rysselberghe; P Barlow; S Rozenberg Journal: Ultrasound Obstet Gynecol Date: 2004-03 Impact factor: 7.299
Authors: Eric D Levens; Brian W Whitcomb; Jonathan D Kort; Donna Materia-Hoover; Frederick W Larsen Journal: Fertil Steril Date: 2008-02-04 Impact factor: 7.329
Authors: Catherine Y Spong; Vincenzo Berghella; Katharine D Wenstrom; Brian M Mercer; George R Saade Journal: Obstet Gynecol Date: 2012-11 Impact factor: 7.661
Authors: J Vissers; T C Sluckin; C C Repelaer van Driel-Delprat; R Schats; C J M Groot; C B Lambalk; J W R Twisk; J A F Huirne Journal: Hum Reprod Date: 2020-03-27 Impact factor: 6.918