Literature DB >> 26991455

Defining 'nutraceuticals': neither nutritious nor pharmaceutical.

Jeffrey K Aronson1.   

Abstract

There are widespread inconsistencies and contradictions in the many published definitions of 'nutraceuticals' and 'functional foods', demonstrating wholesale uncertainty about what they actually are. Furthermore, in a 2014 lecture, the inventor of the term 'nutraceutical', confessing that nutraceuticals do not work, said that 'the quest to demonstrate whether … long-term supplementation [with nutraceuticals] can prevent serious diseases … has come to an end'. Definitions of 'nutraceuticals' and related terms, still widely used, should therefore be explored systematically. There are no internationally agreed definitions of 'nutraceuticals' and 'functional foods', or of similar terms, such as 'health foods', or of terms related to herbal products, which are sometimes referred to as 'nutraceuticals', compounding the confusion. 'Nutraceuticals' and 'functional foods' are vague, nondiscriminatory, unhelpful terms; the evidence suggests that they should be abandoned in favour of more precise terms. The term 'dietary supplement' is widely used to designate formulations that are also called 'nutraceuticals' but it would be better restricted to individual compounds used to treat or prevent deficiencies. 'Fortified foods', sometimes called 'designer foods', are foods to which compounds of proven therapeutic or preventive efficacy (e.g. folic acid) have been added. Other terms, such as 'food', 'foodstuffs', 'eat', 'drink', and 'nutrition', are well defined, as are 'medicinal products' and 'pharmaceutical formulations'. Dietary regimens, such as Mediterranean or nitrate-rich diets or vegetarianism, can affect health. A dietary regimen of this kind can be defined as a programme of food, of a defined kind and/or quantity, prescribed or adopted for the restoration or preservation of health.
© 2016 The British Pharmacological Society.

Entities:  

Keywords:  designer foods; dietary regimens; dietary supplements; fortified foods; functional foods; nutraceuticals

Mesh:

Substances:

Year:  2016        PMID: 26991455      PMCID: PMC5338166          DOI: 10.1111/bcp.12935

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  38 in total

Review 1.  The nutraceutical benefit, part I: green tea.

Authors:  T Sato; G Miyata
Journal:  Nutrition       Date:  2000-04       Impact factor: 4.008

2.  Comparison of melatonin products against USP's nutritional supplements standards and other criteria.

Authors:  H Hahm; J Kujawa; L Augsburger
Journal:  J Am Pharm Assoc (Wash)       Date:  1999 Jan-Feb

Review 3.  Studies on functional foods in Japan--state of the art.

Authors:  S Arai
Journal:  Biosci Biotechnol Biochem       Date:  1996-01       Impact factor: 2.043

4.  Medication errors: definitions and classification.

Authors:  Jeffrey K Aronson
Journal:  Br J Clin Pharmacol       Date:  2009-06       Impact factor: 4.335

Review 5.  Enzymes approved for human therapy: indications, mechanisms and adverse effects.

Authors:  Brian A Baldo
Journal:  BioDrugs       Date:  2015-02       Impact factor: 5.807

Review 6.  A perspective on vegetarian dietary patterns and risk of metabolic syndrome.

Authors:  Joan Sabaté; Michelle Wien
Journal:  Br J Nutr       Date:  2015-04       Impact factor: 3.718

7.  Nutraceuticals: is there good science behind the hype?

Authors:  Jeroen Schmitt; Albert Ferro
Journal:  Br J Clin Pharmacol       Date:  2013-03       Impact factor: 4.335

8.  Melatonin dietary supplement as an anti-aging therapy for age-related bone loss.

Authors:  Isabel F Tresguerres; Faleh Tamimi; Hazem Eimar; Jake E Barralet; Santiago Prieto; Jesús Torres; José Luis Calvo-Guirado; Jesús A F Tresguerres
Journal:  Rejuvenation Res       Date:  2014-08       Impact factor: 4.663

9.  Opportunities in the nutrition and food sciences: research challenges and the next generation of investigators. Special Committee of the Food and Nutrition Board of the Institute of Medicine, National Academy of Sciences.

Authors: 
Journal:  J Nutr       Date:  1994-06       Impact factor: 4.798

Review 10.  Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management.

Authors:  Pilar L Magoulas; Ayman W El-Hattab
Journal:  Orphanet J Rare Dis       Date:  2012-09-18       Impact factor: 4.123

View more
  38 in total

1.  Are nutraceuticals the modern panacea? From myth to science.

Authors:  Pietro Minuz; Giampaolo Velo; Francesco Violi; Albert Ferro
Journal:  Br J Clin Pharmacol       Date:  2017-01       Impact factor: 4.335

2.  Principles of pharmacological research of nutraceuticals.

Authors:  Ruth Andrew; Angelo A Izzo
Journal:  Br J Pharmacol       Date:  2017-06       Impact factor: 8.739

Review 3.  Defining 'nutraceuticals': neither nutritious nor pharmaceutical.

Authors:  Jeffrey K Aronson
Journal:  Br J Clin Pharmacol       Date:  2016-04-25       Impact factor: 4.335

Review 4.  Nutraceuticals' Novel Formulations: The Good, the Bad, the Unknown and Patents Involved.

Authors:  Nada A Helal; Heba A Eassa; Ahmed M Amer; Mohamed A Eltokhy; Ivan Edafiogho; Mohamed I Nounou
Journal:  Recent Pat Drug Deliv Formul       Date:  2019

Review 5.  Medical Devices: Definition, Classification, and Regulatory Implications.

Authors:  Jeffrey K Aronson; Carl Heneghan; Robin E Ferner
Journal:  Drug Saf       Date:  2020-02       Impact factor: 5.606

Review 6.  Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals.

Authors:  Elizabeth M Williamson; Xinmin Liu; Angelo A Izzo
Journal:  Br J Pharmacol       Date:  2020-02-06       Impact factor: 8.739

Review 7.  Anticancer Effects of Nutraceuticals in the Mediterranean Diet: An Epigenetic Diet Model.

Authors:  Rosa Divella; Antonella Daniele; Eufemia Savino; Angelo Paradiso
Journal:  Cancer Genomics Proteomics       Date:  2020 Jul-Aug       Impact factor: 4.069

Review 8.  The effect of nutraceuticals on multiple signaling pathways in cardiac fibrosis injury and repair.

Authors:  Parinaz Zivarpour; Željko Reiner; Jamal Hallajzadeh; Liaosadat Mirsafaei; Zatollah Asemi
Journal:  Heart Fail Rev       Date:  2022-01       Impact factor: 4.214

9.  Preliminary Results of CitraVes™ Effects on Low Density Lipoprotein Cholesterol and Waist Circumference in Healthy Subjects after 12 Weeks: A Pilot Open-Label Study.

Authors:  Stefania Raimondo; Dragana Nikolic; Alice Conigliaro; Gianluca Giavaresi; Bruna Lo Sasso; Rosaria Vincenza Giglio; Roberta Chianetta; Mauro Manno; Samuele Raccosta; Valeria Corleone; Giovanni Ferrante; Roberto Citarrella; Manfredi Rizzo; Giacomo De Leo; Marcello Ciaccio; Giuseppe Montalto; Riccardo Alessandro
Journal:  Metabolites       Date:  2021-04-27

Review 10.  Indicators and Recommendations for Assessing Sustainable Healthy Diets.

Authors:  Maite M Aldaya; Francisco C Ibañez; Paula Domínguez-Lacueva; María Teresa Murillo-Arbizu; Mar Rubio-Varas; Beatriz Soret; María José Beriain
Journal:  Foods       Date:  2021-05-02
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.