Literature DB >> 31577201

Nutraceuticals' Novel Formulations: The Good, the Bad, the Unknown and Patents Involved.

Nada A Helal1, Heba A Eassa2, Ahmed M Amer3, Mohamed A Eltokhy4, Ivan Edafiogho5, Mohamed I Nounou5.   

Abstract

Traditional nutraceuticals and cosmeceuticals hold pragmatic nature with respect to their definitions, claims, purposes and marketing strategies. Their definitions are not well established worldwide. They also have different regulatory definitions and registration regulatory processes in different parts of the world. Global prevalence of nutraceuticals and cosmeceuticals is noticeably high with large market share with minimal regulation compared to traditional drugs. The global market is flooded with nutraceuticals and cosmeceuticals claiming to be of natural origin and sold with a therapeutic claim by major online retail stores such as Amazon and eBay. Apart from the traditional formulations, many manufacturers and researchers use novel formulation technologies in nutraceutical and cosmeceutical formulations for different reasons and objectives. Manufacturers tend to differentiate their products with novel formulations to increase market appeal and sales. On the other hand, researchers use novel strategies to enhance nutraceuticals and cosmeceuticals activity and safety. The objective of this review is to assess the current patents and research adopting novel formulation strategies in nutraceuticals and cosmeceuticals. Patents and research papers investigating nutraceutical and cosmeceutical novel formulations were surveyed for the past 15 years. Various nanosystems and advanced biotechnology systems have been introduced to improve the therapeutic efficacy, safety and market appeal of nutraceuticals and cosmeceuticals, including liposomes, polymeric micelles, quantum dots, nanoparticles, and dendrimers. This review provides an overview of nutraceuticals and cosmeceuticals current technologies, highlighting their pros, cons, misconceptions, regulatory definitions and market. This review also aims in separating the science from fiction in the nutraceuticals and cosmeceuticals development, research and marketing. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Nutraceuticals; adulteration; counterfeiting; fortified foods; nanocarriers; novel drug delivery; regulatoryzzm321990affairs; toxicity.

Mesh:

Substances:

Year:  2019        PMID: 31577201      PMCID: PMC6806606          DOI: 10.2174/1872211313666190503112040

Source DB:  PubMed          Journal:  Recent Pat Drug Deliv Formul        ISSN: 1872-2113


  145 in total

1.  Role of nutraceuticals in human health.

Authors:  Lipi Das; Eshani Bhaumik; Utpal Raychaudhuri; Runu Chakraborty
Journal:  J Food Sci Technol       Date:  2011-02-26       Impact factor: 2.701

2.  Solid lipid nanoparticles: a modern formulation approach in drug delivery system.

Authors:  S Mukherjee; S Ray; R S Thakur
Journal:  Indian J Pharm Sci       Date:  2009-07       Impact factor: 0.975

3.  Grafting of gallic acid onto chitosan enhances antioxidant activities and alters rheological properties of the copolymer.

Authors:  Minhao Xie; Bing Hu; Yan Wang; Xiaoxiong Zeng
Journal:  J Agric Food Chem       Date:  2014-09-08       Impact factor: 5.279

4.  Dietary calcium intake and risk of fracture and osteoporosis: prospective longitudinal cohort study.

Authors:  Eva Warensjö; Liisa Byberg; Håkan Melhus; Rolf Gedeborg; Hans Mallmin; Alicja Wolk; Karl Michaëlsson
Journal:  BMJ       Date:  2011-05-24

Review 5.  New concepts in nutraceuticals as alternative for pharmaceuticals.

Authors:  Hamid Nasri; Azar Baradaran; Hedayatollah Shirzad; Mahmoud Rafieian-Kopaei
Journal:  Int J Prev Med       Date:  2014-12

Review 6.  Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems.

Authors:  Andreia Granja; Iúri Frias; Ana Rute Neves; Marina Pinheiro; Salette Reis
Journal:  Biomed Res Int       Date:  2017-07-16       Impact factor: 3.411

7.  In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model.

Authors:  Antonietta Stellavato; Anna Virginia Adriana Pirozzi; Francesca de Novellis; Ilaria Scognamiglio; Valentina Vassallo; Andrea Maria Giori; Mario De Rosa; Chiara Schiraldi
Journal:  Lipids Health Dis       Date:  2018-02-05       Impact factor: 3.876

8.  Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro.

Authors:  Simona Serini; Roberta Cassano; Paola Antonia Corsetto; Angela Maria Rizzo; Gabriella Calviello; Sonia Trombino
Journal:  Int J Mol Sci       Date:  2018-02-16       Impact factor: 5.923

Review 9.  Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues.

Authors:  Kanika Madaan; Sandeep Kumar; Neelam Poonia; Viney Lather; Deepti Pandita
Journal:  J Pharm Bioallied Sci       Date:  2014-07

Review 10.  Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations.

Authors:  Jaison Jeevanandam; Ahmed Barhoum; Yen S Chan; Alain Dufresne; Michael K Danquah
Journal:  Beilstein J Nanotechnol       Date:  2018-04-03       Impact factor: 3.649

View more
  19 in total

Review 1.  Functional Foods: An Approach to Modulate Molecular Mechanisms of Alzheimer's Disease.

Authors:  Anna Atlante; Giuseppina Amadoro; Antonella Bobba; Valentina Latina
Journal:  Cells       Date:  2020-10-23       Impact factor: 6.600

Review 2.  The Role of Oxidative Stress in Cardiovascular Aging and Cardiovascular Diseases.

Authors:  Carmine Izzo; Paolo Vitillo; Paola Di Pietro; Valeria Visco; Andrea Strianese; Nicola Virtuoso; Michele Ciccarelli; Gennaro Galasso; Albino Carrizzo; Carmine Vecchione
Journal:  Life (Basel)       Date:  2021-01-15

Review 3.  Are Nutraceuticals Beneficial in Chronic Kidney Disease?

Authors:  Jacek Rysz; Beata Franczyk; Krzysztof Kujawski; Izabela Sacewicz-Hofman; Aleksanda Ciałkowska-Rysz; Anna Gluba-Brzózka
Journal:  Pharmaceutics       Date:  2021-02-06       Impact factor: 6.321

Review 4.  Catechins within the Biopolymer Matrix-Design Concepts and Bioactivity Prospects.

Authors:  Zvezdelina Yaneva; Donika Ivanova
Journal:  Antioxidants (Basel)       Date:  2020-11-26

Review 5.  Polymer-Lipid Pharmaceutical Nanocarriers: Innovations by New Formulations and Production Technologies.

Authors:  Sabrina Bochicchio; Gaetano Lamberti; Anna Angela Barba
Journal:  Pharmaceutics       Date:  2021-02-02       Impact factor: 6.321

Review 6.  Nutritional significance of amino acids, vitamins and minerals as nutraceuticals in poultry production and health - a comprehensive review.

Authors:  Mahmoud Alagawany; Shaaban S Elnesr; Mayada R Farag; Ruchi Tiwari; Mohd Iqbal Yatoo; Kumaragurubaran Karthik; Izabela Michalak; Kuldeep Dhama
Journal:  Vet Q       Date:  2020-12-07       Impact factor: 3.320

Review 7.  Nutraceuticals: Transformation of Conventional Foods into Health Promoters/Disease Preventers and Safety Considerations.

Authors:  Mudhi AlAli; Maream Alqubaisy; Mariam Nasser Aljaafari; Asma Obaid AlAli; Laila Baqais; Aidin Molouki; Aisha Abushelaibi; Kok-Song Lai; Swee-Hua Erin Lim
Journal:  Molecules       Date:  2021-04-27       Impact factor: 4.411

Review 8.  Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease.

Authors:  Tripti Khare; Sushesh Srivatsa Palakurthi; Brijesh M Shah; Srinath Palakurthi; Sharad Khare
Journal:  Int J Mol Sci       Date:  2020-05-31       Impact factor: 5.923

9.  Development of Food Chemistry, Natural Products, and Nutrition Research: Targeting New Frontiers.

Authors:  Antonello Santini; Nicola Cicero
Journal:  Foods       Date:  2020-04-12

Review 10.  Mycopharmaceuticals and Nutraceuticals: Promising Agents to Improve Human Well-Being and Life Quality.

Authors:  Jameel R Al-Obaidi; Nuzul Noorahya Jambari; E I Ahmad-Kamil
Journal:  J Fungi (Basel)       Date:  2021-06-24
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.