| Literature DB >> 26874530 |
Liza Lindenberg1,2, Peter Choyke3,4, William Dahut5,6.
Abstract
Molecular imaging of prostate cancer is in a dynamic phase of development. Currently approved techniques are limited and researchers have been working on novel agents to improve accuracy in targeting and detecting prostate tumors. In addition, the complexity of various prostate cancer states also contributes to the challenges in evaluating suitable radiotracer candidates. We have highlighted nuclear medicine tracers that focus on mechanisms involved in bone metastasis, prostate cancer cell membrane synthesis, amino acid analogs, androgen analogs, and the prostate specific membrane antigen. Encouraging results with many of these innovative radiotracer compounds will not only advance diagnostic capabilities for prostate cancer but open opportunities for theranostic applications to treat this worldwide malignancy.Entities:
Keywords: 11C acetate; 11C/18F choline; 18F DCFBC; 18F DHT; 18F FACBC; 18F NaF; 68Ga PSMA
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Year: 2016 PMID: 26874530 PMCID: PMC6364683 DOI: 10.1007/s11934-016-0575-5
Source DB: PubMed Journal: Curr Urol Rep ISSN: 1527-2737 Impact factor: 3.092