Literature DB >> 26699138

Human embryos and eggs: from long-term storage to biobanking.

Françoise Baylis1, Heather Widdows2.   

Abstract

Genetic relatedness poses significant challenges to traditional practices of medical ethics as concerns the biobanking of human biological samples. In this paper, we first outline the ethical challenges to informed consent and confidentiality as these apply to human biobanks, irrespective of the type of tissue being stored. We argue that the shared nature of genetic information has clear implications for informed consent, and the identifying nature of biological samples and information has clear implications for promises of confidentiality. Next, with regard to the special case of biobanking human embryos and eggs, we consider issues arising from: first, the type of tissues being stored; second, the use to which these tissues are put; and third, how this plays out given the shared and identifying nature of these tissues. Specifically, we examine the differences between human bodily tissues and human reproductive tissues focusing on the assumed potential of the reproductive tissues and on the possible greater emotional attachment to these tissues because of their real and imagined kinship. For some donors there may be a sense of family connection with embryos and eggs they once thought of as 'children-in-waiting'. Finally, we conclude by considering the implications for ethical practice.

Entities:  

Keywords:  Biobanking; Eggs; Embryos; Long-term storage; Reproduction; Research

Mesh:

Year:  2015        PMID: 26699138     DOI: 10.1007/s40592-015-0045-8

Source DB:  PubMed          Journal:  Monash Bioeth Rev        ISSN: 1321-2753


  28 in total

1.  Trends in embryo disposition decisions: patients' responses to a 15-year mailing program.

Authors:  V Provoost; G Pennings; P De Sutter; A Van de Velde; M Dhont
Journal:  Hum Reprod       Date:  2011-12-14       Impact factor: 6.918

Review 2.  Beyond the 'embryo question': human embryonic stem cell ethics in the context of biomaterial donation in the UK.

Authors:  G Bahadur; M Morrison; L Machin
Journal:  Reprod Biomed Online       Date:  2010-12       Impact factor: 3.828

3.  Iceland's plan for genomics research: facts and implications.

Authors:  H T Greely
Journal:  Jurimetrics       Date:  2000

4.  Correcting misperceptions about cryopreserved embryos and stem cell research.

Authors:  Geoffrey P Lomax; Alan O Trounson
Journal:  Nat Biotechnol       Date:  2013-04       Impact factor: 54.908

5.  Policy: Regulate embryos made for research.

Authors:  Insoo Hyun
Journal:  Nature       Date:  2014-05-01       Impact factor: 49.962

Review 6.  Decision making about frozen supernumerary human embryos.

Authors:  Sheryl de Lacey
Journal:  Hum Fertil (Camb)       Date:  2013-03-01       Impact factor: 2.767

7.  Broad Consent for Research With Biological Samples: Workshop Conclusions.

Authors:  Christine Grady; Lisa Eckstein; Ben Berkman; Dan Brock; Robert Cook-Deegan; Stephanie M Fullerton; Hank Greely; Mats G Hansson; Sara Hull; Scott Kim; Bernie Lo; Rebecca Pentz; Laura Rodriguez; Carol Weil; Benjamin S Wilfond; David Wendler
Journal:  Am J Bioeth       Date:  2015       Impact factor: 11.229

Review 8.  Biobanking past, present and future: responsibilities and benefits.

Authors:  Yvonne G De Souza; John S Greenspan
Journal:  AIDS       Date:  2013-01-28       Impact factor: 4.177

9.  Identifiability of DNA data: the need for consistent federal policy.

Authors:  Amy L McGuire
Journal:  Am J Bioeth       Date:  2008-10       Impact factor: 11.229

10.  Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

Authors:  Nils Homer; Szabolcs Szelinger; Margot Redman; David Duggan; Waibhav Tembe; Jill Muehling; John V Pearson; Dietrich A Stephan; Stanley F Nelson; David W Craig
Journal:  PLoS Genet       Date:  2008-08-29       Impact factor: 5.917

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  5 in total

1.  Editorial. Biobanking Eggs and Embryos for Research.

Authors:  Dave Snow; Alana Cattapan
Journal:  Monash Bioeth Rev       Date:  2015-12

2.  Of research and reproduction: defining embryo 'Research' in Canada.

Authors:  Alana Cattapan; Dave Snow
Journal:  Monash Bioeth Rev       Date:  2015-12

3.  Oocyte Biobanks: Old Assumptions and New Challenges.

Authors:  Pamela Tozzo
Journal:  BioTech (Basel)       Date:  2021-02-18

4.  Good practice recommendations for information provision for those involved in reproductive donation.

Authors:  Jackson Kirkman-Brown; Carlos Calhaz-Jorge; Eline A F Dancet; Kersti Lundin; Mariana Martins; Kelly Tilleman; Petra Thorn; Nathalie Vermeulen; Lucy Frith
Journal:  Hum Reprod Open       Date:  2022-02-16

5.  Dual consent? Donors' and recipients' views about involvement in decision-making on the use of embryos created by gamete donation in research.

Authors:  I Baía; C de Freitas; C Samorinha; V Provoost; S Silva
Journal:  BMC Med Ethics       Date:  2019-12-02       Impact factor: 2.652

  5 in total

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