Literature DB >> 26641533

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.

Kristin M Whitworth1, Raymond R R Rowland2, Catherine L Ewen2, Benjamin R Trible2, Maureen A Kerrigan2, Ada G Cino-Ozuna2, Melissa S Samuel1, Jonathan E Lightner3, David G McLaren3, Alan J Mileham3, Kevin D Wells1, Randall S Prather1.   

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Year:  2015        PMID： 26641533     DOI： 10.1038/nbt.3434

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  16 in total

1.  CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin.

Authors:  Dominik J Schaer; Christian A Schaer; Paul W Buehler; Robert A Boykins; Gabriele Schoedon; Abdu I Alayash; Andreas Schaffner
Journal:  Blood       Date:  2005-09-27       Impact factor: 22.113

2.  Pathogenicity of three type 2 porcine reproductive and respiratory syndrome virus strains in experimentally inoculated pregnant gilts.

Authors:  Andrea Ladinig; Susan E Detmer; Kyle Clarke; Carolyn Ashley; Raymond R R Rowland; Joan K Lunney; John C S Harding
Journal:  Virus Res       Date:  2015-03-18       Impact factor: 3.303

3.  Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin.

Authors:  Christian A Schaer; Gabriele Schoedon; Alexander Imhof; Michael O Kurrer; Dominik J Schaer
Journal:  Circ Res       Date:  2006-09-28       Impact factor: 17.367

4.  Targeting the hemoglobin scavenger receptor CD163 in macrophages highly increases the anti-inflammatory potency of dexamethasone.

Authors:  Jonas H Graversen; Pia Svendsen; Frederik Dagnæs-Hansen; Jakob Dal; Gabriele Anton; Anders Etzerodt; Mikkel D Petersen; Peter A Christensen; Holger J Møller; Søren K Moestrup
Journal:  Mol Ther       Date:  2012-05-29       Impact factor: 11.454

Review 5.  CD163 and inflammation: biological, diagnostic, and therapeutic aspects.

Authors:  Anders Etzerodt; Søren K Moestrup
Journal:  Antioxid Redox Signal       Date:  2012-10-19       Impact factor: 8.401

6.  Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos.

Authors:  Kristin M Whitworth; Kiho Lee; Joshua A Benne; Benjamin P Beaton; Lee D Spate; Stephanie L Murphy; Melissa S Samuel; Jiude Mao; Chad O'Gorman; Eric M Walters; Clifton N Murphy; John Driver; Alan Mileham; David McLaren; Kevin D Wells; Randall S Prather
Journal:  Biol Reprod       Date:  2014-08-06       Impact factor: 4.285

7.  Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China.

Authors:  Yufeng Li; Xinglong Wang; Kuntao Bo; Xianwei Wang; Bo Tang; Baoshou Yang; Wenming Jiang; Ping Jiang
Journal:  Vet J       Date:  2007-09-14       Impact factor: 2.688

8.  Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption.

Authors:  Anders Etzerodt; Mads Kjolby; Marianne Jensby Nielsen; Maciej Maniecki; Pia Svendsen; Søren Kragh Moestrup
Journal:  Antioxid Redox Signal       Date:  2012-08-29       Impact factor: 8.401

9.  An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus.

Authors:  Randall S Prather; Raymond R R Rowland; Catherine Ewen; Benjamin Trible; Maureen Kerrigan; Bhupinder Bawa; Jennifer M Teson; Jiude Mao; Kiho Lee; Melissa S Samuel; Kristin M Whitworth; Clifton N Murphy; Tina Egen; Jonathan A Green
Journal:  J Virol       Date:  2013-06-19       Impact factor: 5.103

10.  Genome-wide association and genomic prediction for host response to porcine reproductive and respiratory syndrome virus infection.

Authors:  Nicholas J Boddicker; Angelica Bjorkquist; Raymond R R Rowland; Joan K Lunney; James M Reecy; Jack C M Dekkers
Journal:  Genet Sel Evol       Date:  2014-03-04       Impact factor: 4.297
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  130 in total

1.  Porcine reproductive and respiratory syndrome virus neutralizing antibodies provide in vivo cross-protection to PRRSV1 and PRRSV2 viral challenge.

Authors:  Sally R Robinson; Michael C Rahe; Diem K Gray; Kyra V Martins; Michael P Murtaugh
Journal:  Virus Res       Date:  2018-02-03       Impact factor: 3.303

2.  The ethics of genome editing in non-human animals: a systematic review of reasons reported in the academic literature.

Authors:  Nienke de Graeff; Karin R Jongsma; Josephine Johnston; Sarah Hartley; Annelien L Bredenoord
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-05-13       Impact factor: 6.237

Review 3.  Genome editing and genetic engineering in livestock for advancing agricultural and biomedical applications.

Authors:  Bhanu P Telugu; Ki-Eun Park; Chi-Hun Park
Journal:  Mamm Genome       Date:  2017-07-15       Impact factor: 2.957

4.  Efficient CRISPR/Cas9-mediated gene editing in Guangdong small-ear spotted pig cells using an optimized electrotransfection method.

Authors:  Yan-Yan Wei; Qun-Mei Zhan; Xiang-Xing Zhu; Ai-Fen Yan; Juan Feng; Lian Liu; Jian-Hao Li; Dong-Sheng Tang
Journal:  Biotechnol Lett       Date:  2020-06-03       Impact factor: 2.461

5.  20 years of Nature Biotechnology bioengineering research.

Authors:  Laura DeFrancesco; Charles Schmidt; Emily Waltz
Journal:  Nat Biotechnol       Date:  2016-03       Impact factor: 54.908

Review 6.  Strategies to enable the adoption of animal biotechnology to sustainably improve global food safety and security.

Authors:  Mark Tizard; Eric Hallerman; Scott Fahrenkrug; Martina Newell-McGloughlin; John Gibson; Frans de Loos; Stefan Wagner; Götz Laible; Jae Yong Han; Michael D'Occhio; Lisa Kelly; John Lowenthal; Kari Gobius; Primal Silva; Caitlin Cooper; Tim Doran
Journal:  Transgenic Res       Date:  2016-05-31       Impact factor: 2.788

7.  Welcome to the CRISPR zoo.

Authors:  Sara Reardon
Journal:  Nature       Date:  2016-03-10       Impact factor: 49.962

8.  Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE).

Authors:  Caitlin A Cooper; Arjun Challagulla; Kristie A Jenkins; Terry G Wise; Terri E O'Neil; Kirsten R Morris; Mark L Tizard; Timothy J Doran
Journal:  Transgenic Res       Date:  2016-11-28       Impact factor: 2.788

9.  Applications of CRISPR technologies in research and beyond.

Authors:  Rodolphe Barrangou; Jennifer A Doudna
Journal:  Nat Biotechnol       Date:  2016-09-08       Impact factor: 54.908

10.  Pharmacologic treatment of donor cells induced to have a Warburg effect-like metabolism does not alter embryonic development in vitro or survival during early gestation when used in somatic cell nuclear transfer in pigs.

Authors:  Bethany R Mordhorst; Stephanie L Murphy; Renee M Ross; Joshua A Benne; Melissa S Samuel; Raissa F Cecil; Bethany K Redel; Lee D Spate; Clifton N Murphy; Kevin D Wells; Jonathan A Green; Randall S Prather
Journal:  Mol Reprod Dev       Date:  2018-03-05       Impact factor: 2.609
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