Literature DB >> 27246007

Strategies to enable the adoption of animal biotechnology to sustainably improve global food safety and security.

Mark Tizard1, Eric Hallerman2, Scott Fahrenkrug3, Martina Newell-McGloughlin4, John Gibson5, Frans de Loos6, Stefan Wagner7, Götz Laible7, Jae Yong Han8, Michael D'Occhio9, Lisa Kelly10, John Lowenthal1, Kari Gobius11, Primal Silva12, Caitlin Cooper1, Tim Doran13.   

Abstract

The ability to generate transgenic animals has existed for over 30 years, and from those early days many predicted that the technology would have beneficial applications in agriculture. Numerous transgenic agricultural animals now exist, however to date only one product from a transgenic animal has been approved for the food chain, due in part to cumbersome regulations. Recently, new techniques such as precision breeding have emerged, which enables the introduction of desired traits without the use of transgenes. The rapidly growing human population, environmental degradation, and concerns related to zoonotic and pandemic diseases have increased pressure on the animal agriculture sector to provide a safe, secure and sustainable food supply. There is a clear need to adopt transgenic technologies as well as new methods such as gene editing and precision breeding to meet these challenges and the rising demand for animal products. To achieve this goal, cooperation, education, and communication between multiple stakeholders-including scientists, industry, farmers, governments, trade organizations, NGOs and the public-is necessary. This report is the culmination of concepts first discussed at an OECD sponsored conference and aims to identify the main barriers to the adoption of animal biotechnology, tactics for navigating those barriers, strategies to improve public perception and trust, as well as industry engagement, and actions for governments and trade organizations including the OECD to harmonize regulations and trade agreements. Specifically, the report focuses on animal biotechnologies that are intended to improve breeding and genetics and currently are not routinely used in commercial animal agriculture. We put forward recommendations on how scientists, regulators, and trade organizations can work together to ensure that the potential benefits of animal biotechnology can be realized to meet the future needs of agriculture to feed the world.

Entities:  

Keywords:  Animal biotechnology; Food safety; Gene editing; Precision breeding; Regulation; Transgenic

Mesh:

Year:  2016        PMID: 27246007     DOI: 10.1007/s11248-016-9965-1

Source DB:  PubMed          Journal:  Transgenic Res        ISSN: 0962-8819            Impact factor:   2.788


  79 in total

1.  Characteristics of long-term cultures of avian primordial germ cells and gonocytes.

Authors:  Yonghong Song; Sivakumar Duraisamy; Jahabar Ali; Jaleel Kizhakkayil; Victor Doss Jacob; Mohammed Ahmed Mohammed; Mohammed A Eltigani; Suresh Amisetty; Manoj Kumar Shukla; Robert J Etches; Marie-Cecile van de Lavoir
Journal:  Biol Reprod       Date:  2014-01-23       Impact factor: 4.285

2.  Generation of eggs from mouse embryonic stem cells and induced pluripotent stem cells.

Authors:  Katsuhiko Hayashi; Mitinori Saitou
Journal:  Nat Protoc       Date:  2013-07-11       Impact factor: 13.491

Review 3.  Fatal attraction: the intuitive appeal of GMO opposition.

Authors:  Stefaan Blancke; Frank Van Breusegem; Geert De Jaeger; Johan Braeckman; Marc Van Montagu
Journal:  Trends Plant Sci       Date:  2015-04-10       Impact factor: 18.313

Review 4.  Are good ideas enough? The impact of socio-economic and regulatory factors on GMO commercialisation.

Authors:  Núria Vàzquez-Salat
Journal:  Biol Res       Date:  2013       Impact factor: 5.612

5.  Opinion: A new paradigm for regulating genetically engineered animals that are used as food.

Authors:  J D Murray; E A Maga
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-29       Impact factor: 11.205

6.  Characterization of recombinant human C1 inhibitor secreted in milk of transgenic rabbits.

Authors:  Harrie A van Veen; Jaco Koiter; Carla J M Vogelezang; Noucha van Wessel; Tijtje van Dam; Ingeborg Velterop; Kristina van Houdt; Luc Kupers; Danielle Horbach; Mourad Salaheddine; Jan H Nuijens; Maurice L M Mannesse
Journal:  J Biotechnol       Date:  2012-09-17       Impact factor: 3.307

7.  TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis.

Authors:  Haibo Wu; Yongsheng Wang; Yan Zhang; Mingqi Yang; Jiaxing Lv; Jun Liu; Yong Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-02       Impact factor: 11.205

Review 8.  Metallothionein-human GH fusion genes stimulate growth of mice.

Authors:  R D Palmiter; G Norstedt; R E Gelinas; R E Hammer; R L Brinster
Journal:  Science       Date:  1983-11-18       Impact factor: 47.728

9.  Stepwise differentiation from naïve state pluripotent stem cells to functional primordial germ cells through an epiblast-like state.

Authors:  Katsuhiko Hayashi; Mitinori Saitou
Journal:  Methods Mol Biol       Date:  2013

10.  Efficient genetic modification and germ-line transmission of primordial germ cells using piggyBac and Tol2 transposons.

Authors:  Joni Macdonald; Lorna Taylor; Adrian Sherman; Koichi Kawakami; Yoshiko Takahashi; Helen M Sang; Michael J McGrew
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-14       Impact factor: 11.205

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  5 in total

Review 1.  Primordial germ cell-mediated transgenesis and genome editing in birds.

Authors:  Jae Yong Han; Young Hyun Park
Journal:  J Anim Sci Biotechnol       Date:  2018-01-31

2.  Efficient TALEN-mediated gene targeting of chicken primordial germ cells.

Authors:  Lorna Taylor; Daniel F Carlson; Sunil Nandi; Adrian Sherman; Scott C Fahrenkrug; Michael J McGrew
Journal:  Development       Date:  2017-02-07       Impact factor: 6.868

3.  Potential benefits of gene editing for the future of poultry farming.

Authors:  Mark L Tizard; Kristie A Jenkins; Caitlin A Cooper; Mark E Woodcock; Arjun Challagulla; Timothy J Doran
Journal:  Transgenic Res       Date:  2019-08       Impact factor: 2.788

4.  Genetic characteristics of polycistronic system‑mediated randomly‑inserted multi‑transgenes in miniature pigs and mice.

Authors:  Siyuan Kong; Li Li; Wenjuan Zhu; Leilei Xin; Jinxue Ruan; Yubo Zhang; Shulin Yang; Kui Li
Journal:  Mol Med Rep       Date:  2017-10-20       Impact factor: 2.952

Review 5.  Genome Modification Technologies and Their Applications in Avian Species.

Authors:  Hong Jo Lee; Young Min Kim; Tamao Ono; Jae Yong Han
Journal:  Int J Mol Sci       Date:  2017-10-26       Impact factor: 5.923

  5 in total

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