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22 in total

1. Pyrimidine derivatives as antagonists of pteroylglutamic acid.

Authors: G H HITCHINGS; G B ELION
Journal: J Biol Chem Date: 1948-06 Impact factor: 5.157

2. THE EFFECTS OF PYRIMIDINES ON THE GROWTH OF LACTOBACILLUS CASEI.

Authors: G H Hitchings; E A Falco; M B Sherwood
Journal: Science Date: 1945-09-07 Impact factor: 47.728

3. PHOSPHORUS COMPOUNDS OF MUSCLE AND LIVER.

Authors: C H Fiske; Y Subbarow
Journal: Science Date: 1929-10-18 Impact factor: 47.728

4. Antimalarials as antagonists of purines and pteroylglutamic acid.

Authors: E A FALCO; G H HITCHINGS
Journal: Nature Date: 1949-07-16 Impact factor: 49.962

5. The effects of the folic acid antagonists and 2,6-diaminopurine on neoplastic disease, with special reference to acute leukemia.

Authors: J H BURCHENAL; D A KARNOFSKY; E M KINGSLEY-PILLERS; C M SOUTHAM; W P L MYERS; G C ESCHER; L F CRAVER; H W DARGEON; C P RHOADS
Journal: Cancer Date: 1951-05 Impact factor: 6.860

6. A biochemical approach to chemotherapy.

Authors: G H Hitchings
Journal: Drug Intell Clin Pharm Date: 1982-11

7. Biochemical and antitumor effects of 5,8-dideazaisopteroylglutamate, a unique quinazoline inhibitor of thymidylate synthase.

Authors: D J Fernandes; J R Bertino; J B Hynes
Journal: Cancer Res Date: 1983-03 Impact factor: 12.701

Review 8. The anatomy and taxonomy of protein structure.

Authors: J S Richardson
Journal: Adv Protein Chem Date: 1981

Review 9. Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.

Authors: G H Hitchings
Journal: Cancer Res Date: 1969-11 Impact factor: 12.701

10. Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.

Authors: D A Matthews; S L Smith; D P Baccanari; J J Burchall; S J Oatley; J Kraut
Journal: Biochemistry Date: 1986-07-29 Impact factor: 3.162

17 in total

Review 1. Molecular recognition: models for drug design.

Authors: R J Breckenridge
Journal: Experientia Date: 1991-12-01

2. X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design.

Authors: Brad C Bennett; Qun Wan; Md Faiz Ahmad; Paul Langan; Chris G Dealwis
Journal: J Struct Biol Date: 2009-05 Impact factor: 2.867

Review 3. Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present.

Authors: Carol Hopkins Sibley; Ric N Price
Journal: Int J Parasitol Drugs Drug Resist Date: 2012-04-20 Impact factor: 4.077

4. An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.

Authors: Henry C Liu; Neema Jamshidi; Yuchen Chen; Satish A Eraly; Sai Yee Cho; Vibha Bhatnagar; Wei Wu; Kevin T Bush; Ruben Abagyan; Bernhard O Palsson; Sanjay K Nigam
Journal: J Biol Chem Date: 2016-07-20 Impact factor: 5.157

5. New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors.

Authors: W J Suling; L E Seitz; R C Reynolds; W W Barrow
Journal: Antimicrob Agents Chemother Date: 2005-11 Impact factor: 5.191

6. Two parallel pathways in the kinetic sequence of the dihydrofolate reductase from Mycobacterium tuberculosis.

Authors: Clarissa M Czekster; An Vandemeulebroucke; John S Blanchard
Journal: Biochemistry Date: 2011-07-22 Impact factor: 3.162

7. Purine and pyrimidine metabolism: still a black box?

Authors: G J Peters; J H Beijnen
Journal: Pharm World Sci Date: 1994-04-15

8. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.

Authors: A'Lissa B Gerum; Jonathan E Ulmer; David P Jacobus; Norman P Jensen; David R Sherman; Carol Hopkins Sibley
Journal: Antimicrob Agents Chemother Date: 2002-11 Impact factor: 5.191

9. Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes.

Authors: Michael J Osborne; Rani P Venkitakrishnan; H Jane Dyson; Peter E Wright
Journal: Protein Sci Date: 2003-10 Impact factor: 6.725

10. Moritella cold-active dihydrofolate reductase: are there natural limits to optimization of catalytic efficiency at low temperature?

Authors: Ying Xu; Georges Feller; Charles Gerday; Nicolas Glansdorff
Journal: J Bacteriol Date: 2003-09 Impact factor: 3.490