| Literature DB >> 26476738 |
DeWayne C Lazenby1,2, Georgios D Sideridis3, Noelle Huntington3, Matthew Prante4,5, Philip S Dale6, Suzanne Curtin7, Lisa Henkel7, Jana M Iverson8, Leslie Carver9, Karen Dobkins9, Natacha Akshoomoff9, Daina Tagavi10,11, Charles A Nelson3,12, Helen Tager-Flusberg10.
Abstract
Little is known about early language development in infants who later develop autism spectrum disorder (ASD). We analyzed prospective data from 346 infants, some of whom were at high risk for developing ASD, to determine if language differences could be detected at 12 months of age in the infants who later were diagnosed with ASD. Analyses revealed lower receptive and expressive language scores in infants who later were diagnosed with ASD. Controlling for overall ability to understand and produce single words, a Rasch analysis indicated that infants who later developed ASD had a higher degree of statistically unexpected word understanding and production. At 12 months of age, quantitative and qualitative language patterns distinguished infants who later developed ASD from those who did not.Entities:
Keywords: Autism spectrum disorder (ASD); Expressive/receptive vocabulary; Infant-sibling; Item response theory; MacArthur-Bates Communicative Developmental Inventories (CDI)
Mesh：
Year: 2016 PMID： 26476738 PMCID： PMC5497684 DOI： 10.1007/s10803-015-2632-1
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257