Literature DB >> 26378126

Assembly of the unusual oxacycles in the orthosomycin antibiotics.

Amie K Boal1, J Martin Bollinger2, Wei-chen Chang3.   

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Year:  2015        PMID： 26378126      PMCID： PMC4593095          DOI： 10.1073/pnas.1514689112

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  11 in total

Review 1.  Lessons from natural molecules.

Authors:  Jon Clardy; Christopher Walsh
Journal:  Nature       Date:  2004-12-16       Impact factor: 49.962

2.  Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics.

Authors:  G Weitnauer; A Mühlenweg; A Trefzer; D Hoffmeister; R D Süssmuth; G Jung; K Welzel; A Vente; U Girreser; A Bechthold
Journal:  Chem Biol       Date:  2001-06

3.  Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

Authors:  P L Roach; I J Clifton; C M Hensgens; N Shibata; C J Schofield; J Hajdu; J E Baldwin
Journal:  Nature       Date:  1997-06-19       Impact factor: 49.962

4.  Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis.

Authors:  Frédéric H Vaillancourt; Ellen Yeh; David A Vosburg; Sarah E O'Connor; Christopher T Walsh
Journal:  Nature       Date:  2005-08-25       Impact factor: 49.962

5.  Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.

Authors:  Leah C Blasiak; Frédéric H Vaillancourt; Christopher T Walsh; Catherine L Drennan
Journal:  Nature       Date:  2006-03-16       Impact factor: 49.962

6.  A new family of iron-dependent halogenases acts on freestanding substrates.

Authors:  Matthew L Hillwig; Xinyu Liu
Journal:  Nat Chem Biol       Date:  2014-09-14       Impact factor: 15.040

7.  Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.

Authors:  Kathryn M McCulloch; Emilianne K McCranie; Jarrod A Smith; Maruf Sarwar; Jeannette L Mathieu; Bryan L Gitschlag; Yu Du; Brian O Bachmann; T M Iverson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-03       Impact factor: 11.205

8.  Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements.

Authors:  Zhihong Zhang; Jing shan Ren; Karl Harlos; Colin H McKinnon; Ian J Clifton; Christopher J Schofield
Journal:  FEBS Lett       Date:  2002-04-24       Impact factor: 4.124

9.  Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.

Authors:  Danny Yun; Mishtu Dey; Luke J Higgins; Feng Yan; Hung-wen Liu; Catherine L Drennan
Journal:  J Am Chem Soc       Date:  2011-06-30       Impact factor: 15.419

10.  Elucidation of the Fe(IV)=O intermediate in the catalytic cycle of the halogenase SyrB2.

Authors:  Shaun D Wong; Martin Srnec; Megan L Matthews; Lei V Liu; Yeonju Kwak; Kiyoung Park; Caleb B Bell; E Ercan Alp; Jiyong Zhao; Yoshitaka Yoda; Shinji Kitao; Makoto Seto; Carsten Krebs; J Martin Bollinger; Edward I Solomon
Journal:  Nature       Date:  2013-07-18       Impact factor: 49.962
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  3 in total

1.  Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance.

Authors:  Noah P Dunham; Wei-Chen Chang; Andrew J Mitchell; Ryan J Martinie; Bo Zhang; Jonathan A Bergman; Lauren J Rajakovich; Bo Wang; Alexey Silakov; Carsten Krebs; Amie K Boal; J Martin Bollinger
Journal:  J Am Chem Soc       Date:  2018-06-04       Impact factor: 15.419

2.  Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1).

Authors:  Noah P Dunham; José M Del Río Pantoja; Bo Zhang; Lauren J Rajakovich; Benjamin D Allen; Carsten Krebs; Amie K Boal; J Martin Bollinger
Journal:  J Am Chem Soc       Date:  2019-06-12       Impact factor: 15.419

3.  Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes.

Authors:  Ryan J Martinie; Christopher J Pollock; Megan L Matthews; J Martin Bollinger; Carsten Krebs; Alexey Silakov
Journal:  Inorg Chem       Date:  2017-09-29       Impact factor: 5.165
  3 in total

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