Literature DB >> 26352096

Understanding the Impact of Obesity on Short-term Outcomes and In-hospital Costs After Instrumented Spinal Fusion.

Dominique M Higgins1, Grant W Mallory, Ryan F Planchard, Ross C Puffer, Mohamed Ali, Marcus J Gates, William E Clifton, Jeffrey T Jacob, Timothy B Curry, Daryl J Kor, Jeremy L Fogelson, William E Krauss, Michelle J Clarke.   

Abstract

BACKGROUND: Obesity rates continue to rise along with the number of obese patients undergoing elective spinal fusion.
OBJECTIVE: To evaluate the impact of obesity on resource utilization and early complications in patients undergoing surgery for degenerative spine disease.
METHODS: A single-institution retrospective analysis was conducted on patients with degenerative spine disease requiring instrumentation between 2008 and 2012. The 801 identified patients were grouped based on a body mass index (BMI) of <30 (nonobese, n = 478), ≥30 and <40 (obese, n = 283), and alternatively BMIs of ≥40 (morbidly obese, n = 40). Baseline characteristics, surgical outcomes and requirements, complications, and cost were compared. Logistic and linear regression analyses were used to determine the strength of association between obesity and outcomes for categorical and continuous data, respectively.
RESULTS: Significant differences were found in comorbidities between cohorts. Multivariate analysis revealed significant associations between obesity and longer anesthesia times (30 minutes, P = .008), and surgical times (24 minutes, P = .02). Additionally, there was a 2.8 times higher rate of wound complications in obese patients (4.2% vs 1.5, P = .03), and 2.5 times higher rate of major medical complications (7.8% vs 3.1, P = .01). Morbid obesity resulted in a 10 times higher rate of wound complications (P < .001). Morbid obesity resulted in a $9078 (P = .005) increase in overall cost of care.
CONCLUSION: Increased BMI is associated with longer operative times, increased complication rates, and increased cost independent of comorbidities. These effects are more pronounced with morbidly obese patients, further supporting a role for preoperative weight loss.

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Mesh:

Year:  2016        PMID: 26352096      PMCID: PMC4839181          DOI: 10.1227/NEU.0000000000001018

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  23 in total

1.  Annual medical spending attributable to obesity: payer-and service-specific estimates.

Authors:  Eric A Finkelstein; Justin G Trogdon; Joel W Cohen; William Dietz
Journal:  Health Aff (Millwood)       Date:  2009-07-27       Impact factor: 6.301

2.  Changes in red blood cell transfusion practice during the turn of the millennium: a retrospective analysis of adult patients undergoing elective open abdominal aortic aneurysm repair using the Mayo database.

Authors:  Timothy R Long; Timothy B Curry; Jolene L Stemmann; Dixie P Bakken; April M Kennedy; Tia M Stringer; Thomas C Bower; Michael J Joyner; C Thomas Wass
Journal:  Ann Vasc Surg       Date:  2010-04-02       Impact factor: 1.466

3.  Anterior and posterior cervical fusion in patients with high body mass index are not associated with greater complications.

Authors:  Rafael A Buerba; Michael C Fu; Jonathan N Grauer
Journal:  Spine J       Date:  2013-10-24       Impact factor: 4.166

4.  Obesity and spine surgery: reassessment based on a prospective evaluation of perioperative complications in elective degenerative thoracolumbar procedures.

Authors:  Sanjay Yadla; Jennifer Malone; Peter G Campbell; Mitchell G Maltenfort; James S Harrop; Ashwini D Sharan; Alexander R Vaccaro; John K Ratliff
Journal:  Spine J       Date:  2010-04-20       Impact factor: 4.166

5.  Lumbar spine fusion in obese and morbidly obese patients.

Authors:  Rahul Vaidya; Julia Carp; Stephen Bartol; Nicole Ouellette; Sandra Lee; Anil Sethi
Journal:  Spine (Phila Pa 1976)       Date:  2009-03-01       Impact factor: 3.468

6.  In-hospital complications and mortality after elective spinal fusion surgery in the united states: a study of the nationwide inpatient sample from 2001 to 2005.

Authors:  Yang Shen; Jonathan C Silverstein; Steven Roth
Journal:  J Neurosurg Anesthesiol       Date:  2009-01       Impact factor: 3.956

7.  National complication rates and disposition after posterior lumbar fusion for acquired spondylolisthesis.

Authors:  Paul S Kalanithi; Chirag G Patil; Maxwell Boakye
Journal:  Spine (Phila Pa 1976)       Date:  2009-08-15       Impact factor: 3.468

8.  Incidence of surgical site infection following adult spinal deformity surgery: an analysis of patient risk.

Authors:  Albert F Pull ter Gunne; C J H M van Laarhoven; David B Cohen
Journal:  Eur Spine J       Date:  2010-01-12       Impact factor: 3.134

9.  Incidence, prevalence, and analysis of risk factors for surgical site infection following adult spinal surgery.

Authors:  Albert F Pull ter Gunne; David B Cohen
Journal:  Spine (Phila Pa 1976)       Date:  2009-06-01       Impact factor: 3.468

10.  Impact of body habitus on perioperative morbidity associated with fusion of the thoracolumbar and lumbar spine.

Authors:  Mohammed F Shamji; Stephen Parker; Chad Cook; Ricardo Pietrobon; Christopher Brown; Robert E Isaacs
Journal:  Neurosurgery       Date:  2009-09       Impact factor: 4.654

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  14 in total

Review 1.  Complexities of spine surgery in obese patient populations: a narrative review.

Authors:  Gennadiy A Katsevman; Scott D Daffner; Nicholas J Brandmeir; Sanford E Emery; John C France; Cara L Sedney
Journal:  Spine J       Date:  2019-12-24       Impact factor: 4.166

2.  Bariatric bypasses contribute to loss of bone mineral density but reduce axial back pain in morbidly obese patients considering spine surgery.

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2017-01-19

3.  Diabetes and morbid obesity are associated with higher reoperation rates following microvascular decompression surgery: An ACS-NSQIP analysis.

Authors:  Gregory D Arnone; Darian R Esfahani; Steven Papastefan; Neha Rao; Prateek Kumar; Konstantin V Slavin; Ankit I Mehta
Journal:  Surg Neurol Int       Date:  2017-11-01

Review 4.  More risks and complications for elective spine surgery in morbidly obese patients.

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2017-04-26

5.  Thoracolumbar Fusion in Extreme Obesity: Complications and Patient-Reported Outcomes.

Authors:  Jacob R Joseph; Jennifer Neva; Brandon W Smith; Mary O Strasser; Paul Park
Journal:  Int J Spine Surg       Date:  2019-02-22

6.  Anterior lumbar interbody fusion in a lateral decubitus position: technique and outcomes in obese patients.

Authors:  Gregory M Malham; Timothy P Wagner; Matthew H Claydon
Journal:  J Spine Surg       Date:  2019-12

7.  The influence of modifiable risk factors on short-term postoperative outcomes following cervical spine surgery: A retrospective propensity score matched analysis.

Authors:  Shane Shahrestani; Joshua Bakhsheshian; Xiao T Chen; Andy Ton; Alexander M Ballatori; Ben A Strickland; Djani M Robertson; Zorica Buser; Raymond Hah; Patrick C Hsieh; John C Liu; Jeffrey C Wang
Journal:  EClinicalMedicine       Date:  2021-05-15

Review 8.  The Effects of Obesity on Spine Surgery: A Systematic Review of the Literature.

Authors:  Keith L Jackson; John G Devine
Journal:  Global Spine J       Date:  2016-01-15

9.  Use of Allogenic Mesenchymal Cellular Bone Matrix in Anterior and Posterior Cervical Spinal Fusion: A Case Series of 21 Patients.

Authors:  Srikanth Naga Divi; Mark M Mikhael
Journal:  Asian Spine J       Date:  2017-06-15

10.  Physician-Specific Variability in Spine Fusion Patients.

Authors:  Anthony Zou; Joseph Bosco; Themistocles Protopsaltis; James Slover
Journal:  Int J Spine Surg       Date:  2018-03-30
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