Literature DB >> 26324271

Novel plasmid-borne multidrug resistance gene cluster including lsa(E) from a linezolid-resistant Enterococcus faecium isolate of swine origin.

Hongbin Si1, Wan-Jiang Zhang2, Shengbo Chu2, Xiu-Mei Wang2, Lei Dai3, Xin Hua2, Zhimin Dong2, Stefan Schwarz4, Siguo Liu5.   

Abstract

A novel nonconjugative plasmid of 28,489 bp from a porcine linezolid-resistant Enterococcus faecium isolate was completely sequenced. This plasmid harbored a novel type of multiresistance gene cluster that comprised the resistance genes lnu(B), lsa(E), spw, aadE, aphA3, and two copies of erm(B), which account for resistance to macrolides, lincosamides, streptogramins, pleuromutilins, streptomycin, spectinomycin, and kanamycin/neomycin. Structural comparisons suggested that this plasmid might have developed from other enterococcal plasmids by insertion element (IS)-mediated interplasmid recombination processes.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26324271      PMCID： PMC4604366          DOI： 10.1128/AAC.01394-15

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  28 in total

1.  New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.

Authors:  Sybille Schwendener; Vincent Perreten
Journal:  Antimicrob Agents Chemother       Date:  2011-07-18       Impact factor: 5.191

2.  Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci.

Authors:  Elizabeth M Moritz; Paul J Hergenrother
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-26       Impact factor: 11.205

3.  Identification of ABC transporter genes conferring combined pleuromutilin-lincosamide-streptogramin A resistance in bovine methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci.

Authors:  Sarah Wendlandt; Kristina Kadlec; Andrea T Feßler; Stefan Schwarz
Journal:  Vet Microbiol       Date:  2015-04-08       Impact factor: 3.293

4.  An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin.

Authors:  Kavindra V Singh; George M Weinstock; Barbara E Murray
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

5.  Persistent, toxin-antitoxin system-independent, tetracycline resistance-encoding plasmid from a dairy Enterococcus faecium isolate.

Authors:  Xinhui Li; Valente Alvarez; Willis James Harper; Hua H Wang
Journal:  Appl Environ Microbiol       Date:  2011-07-22       Impact factor: 4.792

6.  A novel phenicol exporter gene, fexB, found in enterococci of animal origin.

Authors:  Hebing Liu; Yang Wang; Congming Wu; Stefan Schwarz; Zhangqi Shen; Byeonghwa Jeon; Shuangyang Ding; Qijing Zhang; Jianzhong Shen
Journal:  J Antimicrob Chemother       Date:  2011-11-16       Impact factor: 5.790

7.  Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.

Authors:  Brigitte Malbruny; Anja M Werno; David R Murdoch; Roland Leclercq; Vincent Cattoir
Journal:  Antimicrob Agents Chemother       Date:  2011-01-18       Impact factor: 5.191

8.  Tn1546 is part of a larger plasmid-encoded genetic unit horizontally disseminated among clonal Enterococcus faecium lineages.

Authors:  H Sletvold; P J Johnsen; O-G Wikmark; G S Simonsen; A Sundsfjord; K M Nielsen
Journal:  J Antimicrob Chemother       Date:  2010-06-17       Impact factor: 5.790

9.  Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.

Authors:  Corinna Kehrenberg; Kayode K Ojo; Stefan Schwarz
Journal:  J Antimicrob Chemother       Date:  2004-10-07       Impact factor: 5.790

10.  Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus.

Authors:  Daniel R Gentry; Lynn McCloskey; Michael N Gwynn; Stephen F Rittenhouse; Nicole Scangarella; Ribhi Shawar; David J Holmes
Journal:  Antimicrob Agents Chemother       Date:  2008-10-06       Impact factor: 5.191
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  8 in total

1.  Tn560, a Novel Tn554 Family Transposon from Porcine Methicillin-Resistant Staphylococcus aureus ST398, Carries a Multiresistance Gene Cluster Comprising a Novel spc Gene Variant and the Genes lsa(E) and lnu(B).

Authors:  Xing Ji; Henrike Krüger; Yaxin Wang; Andrea T Feßler; Yang Wang; Stefan Schwarz; Congming Wu
Journal:  Antimicrob Agents Chemother       Date:  2022-03-22       Impact factor: 5.938

2.  Characterization of Spectinomycin Resistance in Streptococcus suis Leads to Two Novel Insights into Drug Resistance Formation and Dissemination Mechanism.

Authors:  Kaisong Huang; Qiang Zhang; Yajing Song; Zhewen Zhang; Anding Zhang; Jingfa Xiao; Meilin Jin
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

Review 3.  Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance.

Authors:  Stefan Schwarz; Jianzhong Shen; Kristina Kadlec; Yang Wang; Geovana Brenner Michael; Andrea T Feßler; Birte Vester
Journal:  Cold Spring Harb Perspect Med       Date:  2016-11-01       Impact factor: 6.915

4.  Assessment of antibiotic susceptibility in Lactobacillus isolates from chickens.

Authors:  Marta Dec; Renata Urban-Chmiel; Dagmara Stępień-Pyśniak; Andrzej Wernicki
Journal:  Gut Pathog       Date:  2017-09-19       Impact factor: 4.181

5.  Molecular Characterization of Enterococcus Isolates From Different Sources in Estonia Reveals Potential Transmission of Resistance Genes Among Different Reservoirs.

Authors:  Erki Aun; Veljo Kisand; Mailis Laht; Kaidi Telling; Piret Kalmus; Ülo Väli; Age Brauer; Maido Remm; Tanel Tenson
Journal:  Front Microbiol       Date:  2021-03-26       Impact factor: 5.640

6.  A Conjugative MDR pMG1-Like Plasmid Carrying the lsa(E) Gene of Enterococcus faecium With Potential Transmission to Staphylococcus aureus.

Authors:  Xiao-Mei Yan; Jing Wang; Xiao-Xia Tao; Hong-Bing Jia; Fan-Liang Meng; Hui Yang; Yuan-Hai You; Bo Zheng; Yuan Hu; Xiao-Xia Bu; Jian-Zhong Zhang
Journal:  Front Microbiol       Date:  2021-06-04       Impact factor: 5.640

Review 7.  Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides-A Review.

Authors:  András Fodor; Birhan Addisie Abate; Péter Deák; László Fodor; Ervin Gyenge; Michael G Klein; Zsuzsanna Koncz; Josephat Muvevi; László Ötvös; Gyöngyi Székely; Dávid Vozik; László Makrai
Journal:  Pathogens       Date:  2020-06-29

8.  Identification and antibiotic susceptibility of lactobacilli isolated from turkeys.

Authors:  Marta Dec; Anna Nowaczek; Dagmara Stępień-Pyśniak; Jacek Wawrzykowski; Renata Urban-Chmiel
Journal:  BMC Microbiol       Date:  2018-10-29       Impact factor: 3.605
  8 in total

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