Maryam Abimbola Mikail1, Idris Adewale Ahmed1, Muhammad Ibrahim2, Norazlanshah Hazali1, Mohammad Syaiful Bahari Abdul Rasad1, Radiah Abdul Ghani1, Ridzwan Hashim1, Ridhwan Abdul Wahab3, Solachuddin Jahuari Arief4, Muhammad Lokman Md Isa5, Samsul Draman6, Mohammad Noor Adros Yahya7. 1. Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. 2. Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. abumaisarah@iium.edu.my. 3. Integrated Centre for Research Animal Care and Use (ICRACU), International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. 4. Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. 5. Kulliyyah of Nursing, International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. 6. Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan Campus, Kuantan, Malaysia. 7. Malaysian Agricultural Research and Development Institute (MARDI), 93050, Kuching, Sarawak, Malaysia.
Abstract
PURPOSE: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available fruits. Baccaurea angulata is an underutilized fruit widely distributed in Borneo Island of Malaysia. The present study was conducted to investigate the effects of B. angulata whole fruit (WF), skin (SK) and pulp (PL) juices on malondialdehyde (MDA) levels and antioxidant enzymes in rabbits fed high-cholesterol diet. METHODS: Thirty-six male rabbits of New Zealand strain were randomly assigned to six groups. Rabbits were fed either a standard pellet (group NC) or a high-cholesterol diet (groups HC, PC, WF, SK and PL). Groups WF, SK and PL were also given 1 ml/kg/day B. angulata WF, SK and PL juices, respectively. RESULTS: Baccaurea angulata had high antioxidant activities. The administration of the various juices significantly reduced (p < 0.05) the concentration of induced plasma MDA. The decrease in the SOD, GPx, CAT and TAC levels caused by cholesterol feeding was also ameliorated with B. angulata. CONCLUSION: Our results show that B. angulata fruit is beneficial in positively influencing and managing oxidative damage.
PURPOSE: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available fruits. Baccaurea angulata is an underutilized fruit widely distributed in Borneo Island of Malaysia. The present study was conducted to investigate the effects of B. angulata whole fruit (WF), skin (SK) and pulp (PL) juices on malondialdehyde (MDA) levels and antioxidant enzymes in rabbits fed high-cholesterol diet. METHODS: Thirty-six male rabbits of New Zealand strain were randomly assigned to six groups. Rabbits were fed either a standard pellet (group NC) or a high-cholesterol diet (groups HC, PC, WF, SK and PL). Groups WF, SK and PL were also given 1 ml/kg/day B. angulata WF, SK and PL juices, respectively. RESULTS:Baccaurea angulata had high antioxidant activities. The administration of the various juices significantly reduced (p < 0.05) the concentration of induced plasma MDA. The decrease in the SOD, GPx, CAT and TAC levels caused by cholesterol feeding was also ameliorated with B. angulata. CONCLUSION: Our results show that B. angulata fruit is beneficial in positively influencing and managing oxidative damage.
Entities:
Keywords:
Antioxidant enzymes; Baccaurea angulata; Malondialdehyde; Underutilized fruit
Authors: R J Nijveldt; E van Nood; D E van Hoorn; P G Boelens; K van Norren; P A van Leeuwen Journal: Am J Clin Nutr Date: 2001-10 Impact factor: 7.045
Authors: Idris Adewale Ahmed; Maryam Abimbola Mikail; Muhammad Bin Ibrahim; Norazlanshah Bin Hazali; Mohammad Syaiful Bahari Abdul Rasad; Radiah Abdul Ghani; Ridhwan Abdul Wahab; Solachuddin Jahuari Arief; Mohammad Noor Adros Yahya Journal: Food Chem Date: 2014-09-30 Impact factor: 7.514
Authors: E S Namıduru; M Tarakçıoğlu; M Namıduru; R Kocabaş; B Erbağcı; I Meram; I Karaoğlan; N Yılmaz; M Cekmen Journal: Asian Pac J Trop Biomed Date: 2011-12