Muhammad Ibrahim1, Maryam Abimbola Mikail2, Idris Adewale Ahmed2,3, Norazlanshah Hazali2, Mohammad Syaiful Bahari Abdul Rasad2, Radiah Abdul Ghani2, Ridzwan Hashim2, Solachuddin Jahuari Arief4, Muhammad Lokman Md Isa5, Samsul Draman6. 1. Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Kuala Lumpur, Malaysia. abumaisarah@iium.edu.my. 2. Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Kuala Lumpur, Malaysia. 3. Department of Biotechnology, Faculty of Science, Lincoln University College Malaysia, Kelana Jaya Campus, Petaling Jaya, 47301, Selangor, Malaysia. 4. Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan Campus, Kuala Lumpur, Malaysia. 5. Kulliyyah of Nursing, International Islamic University Malaysia, Kuantan Campus, Kuala Lumpur, Malaysia. 6. Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan Campus, Kuala Lumpur, Malaysia.
Abstract
PURPOSE: Baccaurea angulata (common names: belimbing dayak or belimbing hutan) is a Malaysian underutilized fruit. The preliminary work on B. angulata fruit juice showed that it possesses antioxidant properties. Therefore, further work is needed to confirm the efficacy and proper dosage of B. angulata as a potential natural antioxidant. The present study was thus carried out to compare the effects of three different B. angulata whole fruit (WF) juice doses administered at nutritional doses of 0.50, 1.00 and 1.50 ml/kg/day on plasma, aorta and liver malondialdehyde (MDA) levels, antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase) as well as total antioxidant capacity in rabbits fed high-cholesterol diet. METHODS: Thirty-five male rabbits of New Zealand strain were randomly assigned to seven groups. For 12 weeks, group CH was fed 1% cholesterol diet only; group C1 was fed 1% cholesterol diet and 0.50 ml/kg/day B. angulata WF juice; group C2 was fed 1% cholesterol diet and 1.00 ml/kg/day B. angulata WF juice; group C3 was fed 1% cholesterol diet and 1.50 ml/kg/day B. angulata WF juice; group N was fed standard pellet only; group N1 was fed standard pellet and 0.50 ml/kg/day B. angulata WF juice; and group N2 was fed standard pellet and 1.00 ml/kg/day B. angulata WF juice. RESULTS: The three doses reduced the formation of MDA and enhanced the expression of endogenous antioxidant enzymes. The highest dose used (1.50 ml/kg/day) was, however, seen as the most potent. CONCLUSION: Higher doses of B. angulata juice exerted better antioxidant activity.
PURPOSE:Baccaurea angulata (common names: belimbing dayak or belimbing hutan) is a Malaysian underutilized fruit. The preliminary work on B. angulata fruit juice showed that it possesses antioxidant properties. Therefore, further work is needed to confirm the efficacy and proper dosage of B. angulata as a potential natural antioxidant. The present study was thus carried out to compare the effects of three different B. angulata whole fruit (WF) juice doses administered at nutritional doses of 0.50, 1.00 and 1.50 ml/kg/day on plasma, aorta and liver malondialdehyde (MDA) levels, antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase) as well as total antioxidant capacity in rabbits fed high-cholesterol diet. METHODS: Thirty-five male rabbits of New Zealand strain were randomly assigned to seven groups. For 12 weeks, group CH was fed 1% cholesterol diet only; group C1 was fed 1% cholesterol diet and 0.50 ml/kg/day B. angulata WF juice; group C2 was fed 1% cholesterol diet and 1.00 ml/kg/day B. angulata WF juice; group C3 was fed 1% cholesterol diet and 1.50 ml/kg/day B. angulata WF juice; group N was fed standard pellet only; group N1 was fed standard pellet and 0.50 ml/kg/day B. angulata WF juice; and group N2 was fed standard pellet and 1.00 ml/kg/day B. angulata WF juice. RESULTS: The three doses reduced the formation of MDA and enhanced the expression of endogenous antioxidant enzymes. The highest dose used (1.50 ml/kg/day) was, however, seen as the most potent. CONCLUSION: Higher doses of B. angulata juice exerted better antioxidant activity.
Entities:
Keywords:
Antioxidant enzymes; Baccaurea angulata; Doses; Malondialdehyde; Underutilized fruit
Authors: Idris Adewale Ahmed; Maryam Abimbola Mikail; Muhammad Bin Ibrahim; Norazlanshah Bin Hazali; Mohammad Syaiful Bahari Abdul Rasad; Radiah Abdul Ghani; Ridhwan Abdul Wahab; Solachuddin Jahuari Arief; Mohammad Noor Adros Yahya Journal: Food Chem Date: 2014-09-30 Impact factor: 7.514
Authors: Vaios Vasileios Kaminiotis; George Agrogiannis; Panagiotis Konstantopoulos; Vasiliki Androutsopoulou; Laskarina Maria Korou; Ioannis S Vlachos; Ismene A Dontas; Despina Perrea; Dimitrios C Iliopoulos Journal: Lipids Health Dis Date: 2017-09-26 Impact factor: 3.876