OBJECTIVE: To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis. METHODS: Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study. Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically. RESULTS: Serum malondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls (P<0.001). CONCLUSIONS: These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients. Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.
OBJECTIVE: To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis. METHODS: Twenty-four acute intestinal amebiasispatients and 20 healthy controls were enrolled in the present study. Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically. RESULTS: Serum malondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasispatients than healthy controls (P<0.001). CONCLUSIONS: These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasispatients. Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.
Authors: Moisés Martínez-Castillo; Judith Pacheco-Yepez; Nadia Flores-Huerta; Paula Guzmán-Téllez; Rosa A Jarillo-Luna; Luz M Cárdenas-Jaramillo; Rafael Campos-Rodríguez; Mineko Shibayama Journal: Front Cell Infect Microbiol Date: 2018-06-22 Impact factor: 5.293
Authors: M C Arrieta; C Ximénez-García; B B Finlay; M E Nieves-Ramírez; O Partida-Rodríguez; I Laforest-Lapointe; L A Reynolds; E M Brown; A Valdez-Salazar; P Morán-Silva; L Rojas-Velázquez; E Morien; L W Parfrey; M Jin; J Walter; J Torres Journal: mSystems Date: 2018-06-26 Impact factor: 6.496