Literature DB >> 25868751

[New technologies in diabetology. How far are we from a closed loop?].

G Freckmann1.   

Abstract

Today, assistive technologies are highly important in the treatment of diabetes, especially in the therapy of type 1 diabetes. The use of insulin pumps, for example, has become an established form of treatment. Modern insulin pumps offer various functions, such as different basal rate profiles, split delivery of the meal bolus, and integrated bolus calculators. Some pumps are additionally connected to a blood glucose meter or a continuous glucose-monitoring sensor. Several minimally invasive needle-type sensor systems for continuous tissue glucose monitoring are already available. Recent developments aim at increasing the functionality of insulin pumps and the improvements of sensors for continuous glucose monitoring. In addition, many research groups are working on closing the loop between these two components and thus developing an artificial pancreas, which automatically regulates insulin delivery. The first steps have already been taken and bolus calculators or sensor-augmented insulin pumps with suspension of insulin delivery are now available. Many experimental models show promising results. Prior to the implementation of a fully automated system for everyday use, however, partially automated systems that require user input are to be expected. This article aims at giving an overview of the current state of development in the field of diabetes technology.

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Year:  2015        PMID: 25868751     DOI: 10.1007/s00108-014-3627-2

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  23 in total

1.  Reduction in duration of hypoglycemia by automatic suspension of insulin delivery: the in-clinic ASPIRE study.

Authors:  Satish Garg; Ronald L Brazg; Timothy S Bailey; Bruce A Buckingham; Robert H Slover; David C Klonoff; John Shin; John B Welsh; Francine R Kaufman
Journal:  Diabetes Technol Ther       Date:  2012-02-08       Impact factor: 6.118

2.  Continuous glucose profiles in healthy subjects under everyday life conditions and after different meals.

Authors:  Guido Freckmann; Sven Hagenlocher; Annette Baumstark; Nina Jendrike; Ralph C Gillen; Katja Rössner; Cornelia Haug
Journal:  J Diabetes Sci Technol       Date:  2007-09

3.  The PILGRIM study: in silico modeling of a predictive low glucose management system and feasibility in youth with type 1 diabetes during exercise.

Authors:  Thomas Danne; Christiana Tsioli; Olga Kordonouri; Sarah Blaesig; Kerstin Remus; Anirban Roy; Barry Keenan; Scott W Lee; Francine R Kaufman
Journal:  Diabetes Technol Ther       Date:  2014-01-21       Impact factor: 6.118

4.  Effect of local heating on postprandial blood glucose excursions using the InsuPad device: results of an outpatient crossover study.

Authors:  Norbert Hermanns; Gabriel Bitton; André Reimer; Michael Krichbaum; Bernhard Kulzer; Thomas Haak
Journal:  J Diabetes Sci Technol       Date:  2014-08-11

5.  Use of an insulin bolus advisor facilitates earlier and more frequent changes in insulin therapy parameters in suboptimally controlled patients with diabetes treated with multiple daily insulin injection therapy: results of the ABACUS trial.

Authors:  David A Cavan; Ralph Ziegler; Iain Cranston; Katharine Barnard; Jacqueline Ryder; Claudia Vogel; Christopher G Parkin; Walter Koehler; Iris Vesper; Bettina Petersen; Matthias A Schweitzer; Robin S Wagner
Journal:  Diabetes Technol Ther       Date:  2014-04-09       Impact factor: 6.118

6.  Pilot study for assessment of optimal frequency for changing catheters in insulin pump therapy-trouble starts on day 3.

Authors:  Volkmar Schmid; Cloth Hohberg; Marcus Borchert; Thomas Forst; Andreas Pfützner
Journal:  J Diabetes Sci Technol       Date:  2010-07-01

Review 7.  Continuous subcutaneous insulin infusion versus multiple daily insulin injections in patients with diabetes mellitus: systematic review and meta-analysis.

Authors:  K Jeitler; K Horvath; A Berghold; T W Gratzer; K Neeser; T R Pieber; A Siebenhofer
Journal:  Diabetologia       Date:  2008-03-20       Impact factor: 10.122

Review 8.  Continuous glucose monitoring: evidence and consensus statement for clinical use.

Authors:  Andreas Liebl; Helmut R Henrichs; Lutz Heinemann; Guido Freckmann; Eberhard Biermann; Andreas Thomas
Journal:  J Diabetes Sci Technol       Date:  2013-03-01

Review 9.  Severe hypoglycaemia and glycaemic control in Type 1 diabetes: meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion.

Authors:  J C Pickup; A J Sutton
Journal:  Diabet Med       Date:  2008-07       Impact factor: 4.359

10.  Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: meta-analysis of randomised controlled trials using individual patient data.

Authors:  John C Pickup; Suzanne C Freeman; Alex J Sutton
Journal:  BMJ       Date:  2011-07-07
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  2 in total

1.  A New Optimized Percutaneous Access System for CIPII.

Authors:  Rosa Garcia-Verdugo; Michael Erbach; Oliver Schnell
Journal:  J Diabetes Sci Technol       Date:  2017-03-01

Review 2.  Self-measurement of Blood Glucose and Continuous Glucose Monitoring - Is There Only One Future?

Authors:  Lutz Heinemann; Andreas Stuhr; Adam Brown; Guido Freckmann; Marc D Breton; Steven Russell; Lutz Heinemann
Journal:  Eur Endocrinol       Date:  2018-09-10
  2 in total

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