| Literature DB >> 25774083 |
Johannes F de Boer1, Shyam M Srinivas1, B Hyle Park1, Tuan H Pham1, Zhongping Chen1, Thomas E Milner2, J Stuart Nelson1.
Abstract
Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties. In addition, the effects of single polarization state detection on OCT image formation is demonstrated.Entities:
Keywords: Biological tissues; biomedical imaging; birefringence; optical tomography; polarization
Year: 1999 PMID: 25774083 PMCID: PMC4358303 DOI: 10.1109/2944.796347
Source DB: PubMed Journal: IEEE J Sel Top Quantum Electron ISSN: 1077-260X Impact factor: 4.544