Literature DB >> 25762739

Structure and Dynamics of the Native HIV-1 Env Trimer.

James B Munro1, Walther Mothes2.   

Abstract

HIV-1/AIDS remains one of the worst pandemics in human history. Despite tremendous efforts, no effective vaccine has been found. Recent reports give new insights into the structure and dynamics of the HIV-1 Env trimer and renew hopes that a better understanding of Env will translate into new vaccine candidates and more-effective antiretroviral therapies.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 25762739      PMCID： PMC4442439          DOI： 10.1128/JVI.03187-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

1.  In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068.

Authors:  Beata Nowicka-Sans; Yi-Fei Gong; Brian McAuliffe; Ira Dicker; Hsu-Tso Ho; Nannan Zhou; Betsy Eggers; Pin-Fang Lin; Neelanjana Ray; Megan Wind-Rotolo; Li Zhu; Antara Majumdar; David Stock; Max Lataillade; George J Hanna; John D Matiskella; Yasutsugu Ueda; Tao Wang; John F Kadow; Nicholas A Meanwell; Mark Krystal
Journal:  Antimicrob Agents Chemother       Date:  2012-04-30       Impact factor: 5.191

Review 2.  Advances in single-molecule fluorescence methods for molecular biology.

Authors:  Chirlmin Joo; Hamza Balci; Yuji Ishitsuka; Chittanon Buranachai; Taekjip Ha
Journal:  Annu Rev Biochem       Date:  2008       Impact factor: 23.643

3.  Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.

Authors:  Dmitry Lyumkis; Jean-Philippe Julien; Natalia de Val; Albert Cupo; Clinton S Potter; Per-Johan Klasse; Dennis R Burton; Rogier W Sanders; John P Moore; Bridget Carragher; Ian A Wilson; Andrew B Ward
Journal:  Science       Date:  2013-10-31       Impact factor: 47.728

4.  Crystal structure of a soluble cleaved HIV-1 envelope trimer.

Authors:  Jean-Philippe Julien; Albert Cupo; Devin Sok; Robyn L Stanfield; Dmitry Lyumkis; Marc C Deller; Per-Johan Klasse; Dennis R Burton; Rogier W Sanders; John P Moore; Andrew B Ward; Ian A Wilson
Journal:  Science       Date:  2013-10-31       Impact factor: 47.728

5.  How a single patient influenced HIV research--15-year follow-up.

Authors:  Heiko Jessen; Todd M Allen; Hendrik Streeck
Journal:  N Engl J Med       Date:  2014-02-13       Impact factor: 91.245

6.  Molecular architecture of native HIV-1 gp120 trimers.

Authors:  Jun Liu; Alberto Bartesaghi; Mario J Borgnia; Guillermo Sapiro; Sriram Subramaniam
Journal:  Nature       Date:  2008-07-30       Impact factor: 49.962

7.  HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.

Authors:  F Maldarelli; X Wu; L Su; F R Simonetti; W Shao; S Hill; J Spindler; A L Ferris; J W Mellors; M F Kearney; J M Coffin; S H Hughes
Journal:  Science       Date:  2014-06-26       Impact factor: 47.728

8.  Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy.

Authors:  Alberto Bartesaghi; Alan Merk; Mario J Borgnia; Jacqueline L S Milne; Sriram Subramaniam
Journal:  Nat Struct Mol Biol       Date:  2013-10-23       Impact factor: 15.369

9.  Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.

Authors:  James B Whitney; Alison L Hill; Srisowmya Sanisetty; Pablo Penaloza-MacMaster; Jinyan Liu; Mayuri Shetty; Lily Parenteau; Crystal Cabral; Jennifer Shields; Stephen Blackmore; Jeffrey Y Smith; Amanda L Brinkman; Lauren E Peter; Sheeba I Mathew; Kaitlin M Smith; Erica N Borducchi; Daniel I S Rosenbloom; Mark G Lewis; Jillian Hattersley; Bei Li; Joseph Hesselgesser; Romas Geleziunas; Merlin L Robb; Jerome H Kim; Nelson L Michael; Dan H Barouch
Journal:  Nature       Date:  2014-07-20       Impact factor: 49.962

10.  A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.

Authors:  Rogier W Sanders; Ronald Derking; Albert Cupo; Jean-Philippe Julien; Anila Yasmeen; Natalia de Val; Helen J Kim; Claudia Blattner; Alba Torrents de la Peña; Jacob Korzun; Michael Golabek; Kevin de Los Reyes; Thomas J Ketas; Marit J van Gils; C Richter King; Ian A Wilson; Andrew B Ward; P J Klasse; John P Moore
Journal:  PLoS Pathog       Date:  2013-09-19       Impact factor: 6.823
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  41 in total

1.  Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.

Authors:  Adel A Rashad; Kriti Acharya; Ann Haftl; Rachna Aneja; Alexej Dick; Andrew P Holmes; Irwin Chaiken
Journal:  Org Biomol Chem       Date:  2017-09-26       Impact factor: 3.876

2.  Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies.

Authors:  Gilad Kaplan; Anna Roitburd-Berman; George K Lewis; Jonathan M Gershoni
Journal:  J Virol       Date:  2016-04-14       Impact factor: 5.103

3.  CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5.

Authors:  Xihe Zhang; Jing Shi; Xusheng Qiu; Qingqing Chai; Dylan A Frabutt; Richard C Schwartz; Yong-Hui Zheng
Journal:  J Virol       Date:  2019-06-28       Impact factor: 5.103

4.  Plasticity and Epitope Exposure of the HIV-1 Envelope Trimer.

Authors:  Rebecca L R Powell; Maxim Totrov; Vincenza Itri; Xiaomei Liu; Alisa Fox; Susan Zolla-Pazner
Journal:  J Virol       Date:  2017-08-10       Impact factor: 5.103

Review 5.  How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design.

Authors:  Marie Pancera; Anita Changela; Peter D Kwong
Journal:  Curr Opin HIV AIDS       Date:  2017-05       Impact factor: 4.283

6.  Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.

Authors:  Haoqing Wang; Alexander A Cohen; Rachel P Galimidi; Harry B Gristick; Grant J Jensen; Pamela J Bjorkman
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-31       Impact factor: 11.205

7.  The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization.

Authors:  Hamid Salimi; Jacklyn Johnson; Manuel G Flores; Michael S Zhang; Yunxia O'Malley; Jon C Houtman; Patrick M Schlievert; Hillel Haim
Journal:  J Biol Chem       Date:  2019-11-22       Impact factor: 5.157

Review 8.  Survivors Remorse: antibody-mediated protection against HIV-1.

Authors:  George K Lewis; Marzena Pazgier; Anthony L DeVico
Journal:  Immunol Rev       Date:  2017-01       Impact factor: 12.988

9.  HIV-1 Cross-Reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Nonhuman Primates.

Authors:  Yimeng Wang; Sijy O'Dell; Hannah L Turner; Chi-I Chiang; Lin Lei; Javier Guenaga; Richard Wilson; Paola Martinez-Murillo; Nicole Doria-Rose; Andrew B Ward; John R Mascola; Richard T Wyatt; Gunilla B Karlsson Hedestam; Yuxing Li
Journal:  J Virol       Date:  2017-10-13       Impact factor: 5.103

Review 10.  Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41.

Authors:  Hyun A Yi; Brian C Fochtman; Robert C Rizzo; Amy Jacobs
Journal:  Curr HIV Res       Date:  2016       Impact factor: 1.581
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