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Literature DB >> 24521131

How a single patient influenced HIV research--15-year follow-up.

Heiko Jessen¹, Todd M Allen, Hendrik Streeck.

Abstract

A follow-up report on a patient whose HIV infection was treated early, but briefly, 15 years ago reveals a likely explanation for the control of HIV without antiretroviral therapy.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2014 PMID： 24521131 PMCID： PMC4264571 DOI： 10.1056/NEJMc1308413

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

5 in total

1. Control of HIV despite the discontinuation of antiretroviral therapy.

Authors: J Lisziewicz; E Rosenberg; J Lieberman; H Jessen; L Lopalco; R Siliciano; B Walker; F Lori
Journal: N Engl J Med Date: 1999-05-27 Impact factor: 91.245

2. A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study.

Authors: Felipe García; Montserrat Plana; Mireia Arnedo; Gabriel M Ortiz; José M Miró; Lucia Lopalco; Franco Lori; Tomás Pumarola; Teresa Gallart; José M Gatell
Journal: AIDS Date: 2003-01-03 Impact factor: 4.177

3. Immune control of HIV-1 after early treatment of acute infection.

Authors: E S Rosenberg; M Altfeld; S H Poon; M N Phillips; B M Wilkes; R L Eldridge; G K Robbins; R T D'Aquila; P J Goulder; B D Walker
Journal: Nature Date: 2000-09-28 Impact factor: 49.962

4. Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection.

Authors: Laurent Hocqueloux; Thierry Prazuck; Véronique Avettand-Fenoel; Alain Lafeuillade; Bernard Cardon; Jean-Paul Viard; Christine Rouzioux
Journal: AIDS Date: 2010-06-19 Impact factor: 4.177

5. The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse).

Authors: Mark T Bloch; Don E Smith; Dick Quan; John M Kaldor; John J Zaunders; Kathy Petoumenos; Kathy Irvine; Matthew Law; Pat Grey; Robert J Finlayson; Robert McFarlane; Anthony D Kelleher; Andrew Carr; David A Cooper
Journal: J Acquir Immune Defic Syndr Date: 2006-06 Impact factor: 3.731

5 in total

17 in total

Review 1. Post-Treatment Controllers: Role in HIV "Cure" Research.

Authors: Leslie R Cockerham; Hiroyu Hatano; Steven G Deeks
Journal: Curr HIV/AIDS Rep Date: 2016-02 Impact factor: 5.071

2. Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.

Authors: Zelda Euler; Galit Alter
Journal: AIDS Res Hum Retroviruses Date: 2015-01 Impact factor: 2.205

Review 3. Structure and Dynamics of the Native HIV-1 Env Trimer.

Authors: James B Munro; Walther Mothes
Journal: J Virol Date: 2015-03-11 Impact factor: 5.103

4. The current understanding of overlap between characteristics of HIV-associated neurocognitive disorders and Alzheimer's disease.

Authors: Leah H Rubin; Erin E Sundermann; David J Moore
Journal: J Neurovirol Date: 2019-01-22 Impact factor: 2.643

How a single patient influenced HIV research--15-year follow-up.

1. Control of HIV despite the discontinuation of antiretroviral therapy.

2. A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study.

3. Immune control of HIV-1 after early treatment of acute infection.

4. Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection.

5. The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse).

Review 1. Post-Treatment Controllers: Role in HIV "Cure" Research.

2. Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.

Review 3. Structure and Dynamics of the Native HIV-1 Env Trimer.

4. The current understanding of overlap between characteristics of HIV-associated neurocognitive disorders and Alzheimer's disease.

Review 5. Engineering cord blood to improve engraftment after cord blood transplant.

Review 6. Paediatric HIV infection: the potential for cure.

Review 7. Human immunodeficiency virus vaccines.

8. HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.

Review 9. How elite controllers and posttreatment controllers inform our search for an HIV-1 cure.

Review 10. Hematopoietic Stem and Immune Cells in Chronic HIV Infection.