Literature DB >> 2568743

Effect of beta-adrenoceptor blocking drugs on 32P incorporation into and arachidonic acid liberation from phospholipids in stimulated rat mast cells.

J Pecivová1, K Drábiková, R Nosál.   

Abstract

The lipophilic beta-adrenoceptor blocking (BAB) drugs metipranolol, propranolol and exaprolol significantly decreased 48/80- and A23187-induced 32P incorporation into rat mast cell phospholipids. Exaprolol was the most active, followed by propranolol and metipranolol. Atenolol and metipranolol significantly decreased the 48/80-stimulated, and metipranolol and exaprolol the A23187-stimulated 3H-arachidonic acid liberation from isolated mast cells.

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Year:  1989        PMID： 2568743     DOI： 10.1007/BF02222189

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  10 in total

1.  Action of calcium channel and beta-adrenergic blocking agents in bilayer lipid membranes.

Authors:  B Shi; H T Tien
Journal:  Biochim Biophys Acta       Date:  1986-07-24

2.  Local anesthetics, chlorpromazine and propranolol inhibit stimulus-activation of phospholipase A2 in human platelets.

Authors:  J Y Vanderhoek; M B Feinstein
Journal:  Mol Pharmacol       Date:  1979-07       Impact factor: 4.436

3.  On the relationship between incorporation of 32P into phospholipids and binding of beta-adrenoceptor blocking drugs to isolated mast cells.

Authors:  J Pecivová; K Drábiková; V Jancinová; R Nosál
Journal:  Agents Actions       Date:  1988-04

4.  Classification of beta-blocking agents by their inhibitory effects on phospholipase activity.

Authors:  S Nagai; S Sugiyama; T Ozawa
Journal:  Jpn Circ J       Date:  1986-03

5.  Activation of phospholipid metabolism during mediator release from stimulated rat mast cells.

Authors:  D A Kennerly; T J Sullivan; C W Parker
Journal:  J Immunol       Date:  1979-01       Impact factor: 5.422

6.  Beta-adrenoceptor blocking drugs and calcium transport in isolated rat mast cells.

Authors:  K Drábiková; J Pecivová; R Nosál
Journal:  Agents Actions       Date:  1989-04

7.  On the interaction of beta-adrenoceptor-blocking drugs with isolated mast cells.

Authors:  R Nosál; J Pecivová; K Drábiková
Journal:  Agents Actions       Date:  1985-09

8.  Histamine liberation and membrane fluidisation of mast cells exposed to the beta-adrenoceptor blocking drug propranolol.

Authors:  R Nosál; K Ondrias; J Pecivová; K Drábiková
Journal:  Agents Actions       Date:  1988-04

9.  A major role for phospholipase A2 in antigen-induced arachidonic acid release in rat mast cells.

Authors:  K Yamada; Y Okano; K Miura; Y Nozawa
Journal:  Biochem J       Date:  1987-10-01       Impact factor: 3.857

10.  Differential activation of membrane phospholipid turnover by compound 48/80 and ionophore A23187 in rat mast cells.

Authors:  A Imai; Y Ishizuka; S Nakashima; Y Nozawa
Journal:  Arch Biochem Biophys       Date:  1984-07       Impact factor: 4.013
  10 in total
  2 in total

1.  Effect of chloroquine on arachidonic acid pathway in isolated mast cells.

Authors:  K Drábiková; J Pecivová; R Nosál
Journal:  Inflamm Res       Date:  1996-03       Impact factor: 4.575

2.  The effect of beta-adrenoceptor blocking drugs on histamine liberation, prostaglandin synthesis and phospholipid turnover in isolated mast cells stimulated with concanavalin A.

Authors:  K Drábiková; J Pecivová; M Petríková; V Jancinová; R Nosál
Journal:  Agents Actions       Date:  1990-04
  2 in total

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