PURPOSE: This study was done to investigate the dynamic changes of the aortic root during systole and diastole in patients with coronary artery calcification (CAC) using dual-source computed tomography (DSCT). MATERIALS AND METHODS: We retrospectively analysed 77 consecutive patients who underwent calcium-scoring and angiographic cardiac DSCT. The long- and short-axis dimensions, axis areas of the aortic annulus, sinotubular junction and ascending aorta at the level of the pulmonary trunk in diastole and systole were measured. Average dimensions and relative areal changes between diastole and systole (%RA) of aortic annulus, sinotubular junction and ascending aorta were compared. RESULTS: Systolic and diastolic long- and short-axis dimensions of the aortic annulus in patients with CAC (n = 44) demonstrated statistically significant differences (27.00 ± 2.84 mm vs. 28.04 ± 2.62 mm; P < 0.001; 21.78 ± 2.55 mm vs. 20.88 ± 2.31 mm; P < 0.001), while differences in average diameters and areas of the aortic annulus were nonsignificant (P > 0.586). Systolic and diastolic axial areas of the sinotubular junction in patients with CAC demonstrated significant differences (7.21 ± 1.80 cm(2) vs. 6.92 ± 1.75 cm(2); P < 0.001). The %RA of the ascending aorta in patients with severe CAC (CAC score >400; n = 15) was significantly reduced compared to patients with minimal-to-moderate CAC (CAC score <400; n = 29; 4.77 ± 2.88 vs. 7.51 ± 3.81, P = 0.014). CONCLUSIONS: In comparison with patients without CAC, the long- and short-axis dimensions of the aortic annulus and areas of the sinotubular junction show significant differences during the cardiac cycle in patients with CAC. The presence of severe CAC significantly influences the flexibility of the wall of the ascending aorta.
PURPOSE: This study was done to investigate the dynamic changes of the aortic root during systole and diastole in patients with coronary artery calcification (CAC) using dual-source computed tomography (DSCT). MATERIALS AND METHODS: We retrospectively analysed 77 consecutive patients who underwent calcium-scoring and angiographic cardiac DSCT. The long- and short-axis dimensions, axis areas of the aortic annulus, sinotubular junction and ascending aorta at the level of the pulmonary trunk in diastole and systole were measured. Average dimensions and relative areal changes between diastole and systole (%RA) of aortic annulus, sinotubular junction and ascending aorta were compared. RESULTS: Systolic and diastolic long- and short-axis dimensions of the aortic annulus in patients with CAC (n = 44) demonstrated statistically significant differences (27.00 ± 2.84 mm vs. 28.04 ± 2.62 mm; P < 0.001; 21.78 ± 2.55 mm vs. 20.88 ± 2.31 mm; P < 0.001), while differences in average diameters and areas of the aortic annulus were nonsignificant (P > 0.586). Systolic and diastolic axial areas of the sinotubular junction in patients with CAC demonstrated significant differences (7.21 ± 1.80 cm(2) vs. 6.92 ± 1.75 cm(2); P < 0.001). The %RA of the ascending aorta in patients with severe CAC (CAC score >400; n = 15) was significantly reduced compared to patients with minimal-to-moderate CAC (CAC score <400; n = 29; 4.77 ± 2.88 vs. 7.51 ± 3.81, P = 0.014). CONCLUSIONS: In comparison with patients without CAC, the long- and short-axis dimensions of the aortic annulus and areas of the sinotubular junction show significant differences during the cardiac cycle in patients with CAC. The presence of severe CAC significantly influences the flexibility of the wall of the ascending aorta.
Authors: R A O'Rourke; B H Brundage; V F Froelicher; P Greenland; S M Grundy; R Hachamovitch; G M Pohost; L J Shaw; W S Weintraub; W L Winters Journal: J Am Coll Cardiol Date: 2000-07 Impact factor: 24.094
Authors: Ronen Gurvitch; John G Webb; Ren Yuan; Mark Johnson; Cameron Hague; Alexander B Willson; Stefan Toggweiler; David A Wood; Jian Ye; Robert Moss; Christopher R Thompson; Stephan Achenbach; James K Min; Troy M Labounty; Ricardo Cury; Jonathon Leipsic Journal: JACC Cardiovasc Interv Date: 2011-11 Impact factor: 11.195
Authors: Richard A P Takx; Antonio Moscariello; U Joseph Schoepf; J Michael Barraza; John W Nance; Gorka Bastarrika; Marco Das; Mathias Meyer; Joachim E Wildberger; Stefan O Schoenberg; Christian Fink; Thomas Henzler Journal: Eur J Radiol Date: 2011-08-09 Impact factor: 3.528
Authors: Laurens F Tops; David A Wood; Victoria Delgado; Joanne D Schuijf; John R Mayo; Sanjeevan Pasupati; Frouke P L Lamers; Ernst E van der Wall; Martin J Schalij; John G Webb; Jeroen J Bax Journal: JACC Cardiovasc Imaging Date: 2008-05
Authors: David A Wood; Laurens F Tops; John R Mayo; Sanjeevan Pasupati; Martin J Schalij; Karin Humphries; May Lee; Abdullah Al Ali; Brad Munt; Rob Moss; Christopher R Thompson; Jeroen J Bax; John G Webb Journal: Am J Cardiol Date: 2009-05-01 Impact factor: 2.778
Authors: Naser Ahmadi; Vahid Nabavi; Fereshteh Hajsadeghi; Ferdinand Flores; Shahdad Azmoon; Hussain Ismaeel; David Shavelle; Song S Mao; Ramin Ebrahimi; Matthew J Budoff Journal: Int J Cardiovasc Imaging Date: 2010-08-15 Impact factor: 2.357